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| Catalog Number | Size | Price |
|---|---|---|
| LS-A1494-50 | 50 µg (1 mg/ml) | $440 |
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PathPlus™ Polyclonal Rabbit anti‑Human Leukotriene B4 Receptor / BLT1 Antibody (Cytoplasmic Domain, IHC) LS‑A1494
PathPlus™ Polyclonal Rabbit anti‑Human Leukotriene B4 Receptor / BLT1 Antibody (Cytoplasmic Domain, IHC) LS‑A1494
Antibody:
Leukotriene B4 Receptor / BLT1 Rabbit anti-Human Polyclonal (Cytoplasmic Domain) Antibody
Application:
IHC, IHC-P, IHC-Fr
Reactivity:
Human, Monkey, Mouse, Rat, Hamster, Horse, Rabbit
Format:
Unconjugated, Unmodified
Overview
Antibody:
Leukotriene B4 Receptor / BLT1 Rabbit anti-Human Polyclonal (Cytoplasmic Domain) Antibody
Application:
IHC, IHC-P, IHC-Fr
Reactivity:
Human, Monkey, Mouse, Rat, Hamster, Horse, Rabbit
Format:
Unconjugated, Unmodified
Specifications
Description
Leukotriene B4 receptor (LTB4R) is receptor that participates in defense against infection. Leukotriene B4 also activates the transcription factor PPAR alpha, resulting in the activation of genes that terminate inflammatory processes (Yokomizo et al., 1997). Although it shows homology to other P2Y receptors, it does not function as a purinoreceptor ( Yokomizo et al., 1997).
References: The UniProt Consortium. Nucleic Acids Res. 47: D506-515 (2019); Nucleic Acids Res. 2016 Jan 4;44(D1):D733-45, PMID:26553804
Target
Human Leukotriene B4 Receptor / BLT1
Synonyms
LTB4R | BLT | BLT1 | BLTR | Blt-1 | Chemokine receptor-like 1 | G protein-coupled receptor 16 | GPR16 | Leukotriene B4 receptor | Leukotriene B4 receptor 1 | G-protein coupled receptor 16 | LTBR1 | p2Y purinoceptor 7 | p2Y7 | LTB4-R 1 | p2RY7 | CMKRL1 | LTB4-R1 | LTB4R1
Host
Rabbit
Reactivity
Human, Monkey, Mouse, Rat, Hamster, Horse, Rabbit
(tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic 16 amino acid peptide from 3rd cytoplasmic domain of human Leukotriene B4 Receptor. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Horse, Rabbit (100%); Bovine (88%); Opossum, Platypus (81%).
Epitope
Cytoplasmic Domain
Specificity
Human Leukotriene B4 Receptor. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Applications
- IHC
- IHC - Paraffin (10 - 15 µg/ml)
- IHC - Frozen
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About Leukotriene B4 Receptor / BLT1
Validation
Brain, Amygdala, neurons and glia
Brain, Amygdala, neurons and glia
Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)
Brain, Alzheimer's, senile plaque
Brain, Alzheimer's, senile plaque
Brain, Cerebellum, Purkinje neuron
Brain, Cerebellum, Purkinje neuron
Anti-Leukotriene B4 Receptor / BLT1 antibody IHC of human Pancreas, Carcinoma and Leukocytes. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-Leukotriene B4 Receptor / BLT1 antibody IHC of human Pancreas, Carcinoma and Leukocytes. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-Leukotriene B4 Receptor antibody IHC of human spleen, red pulp. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-Leukotriene B4 Receptor antibody IHC of human spleen, red pulp. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)
Anti-Leukotriene B4 Receptor / BLT1 antibody IHC of human Lymph Node, Hodgkins Lymphoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-Leukotriene B4 Receptor / BLT1 antibody IHC of human Lymph Node, Hodgkins Lymphoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
See More About...
LSBio Ratings
PathPlus™ Leukotriene B4 Receptor / BLT1 Antibody (Cytoplasmic Domain) for IHC LS-A1494 has an LSBio Rating of
Publications (4.1)
Laboratory Validation Score (5)
Learn more about The LSBio Ratings Algorithm
Publications (2)
Specialized proresolution mediators in the bladder: annexin-A1 normalizes inflammation and bladder dysfunction during bladder outlet obstruction. Francis M Hughes Jr, Shelby N Harper, Brent D Nosé, Armand Allkanjari, Michael T Zheng, Huixia Jin, J Todd Purves. American journal of physiology. Renal physiology. 2021 October;321:F443-F454.
Specialized pro-resolution mediators in the bladder: Receptor expression and recovery of bladder function from cystitis. Francis M Hughes Jr, Armand Allkanjari, Michael R Odom, Huixia Jin, J Todd Purves. Experimental biology and medicine (Maywood, N.J.). 2022 April;247:700-711.
Customer Reviews (0)
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Species:
Human, Monkey
Applications:
IHC, IHC - Paraffin
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Human
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Species:
Human
Applications:
IHC, IHC - Paraffin, Western blot
Species:
Human, Monkey
Applications:
IHC, IHC - Paraffin
Species:
Human
Applications:
IHC, IHC - Paraffin
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 11/21/2024
Date Requested: 11/21/2024
