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Leukotriene B4 Receptor / BLT1
leukotriene B4 receptor
BLT1 is a Chemoattractant Receptor that binds the potent chemoattractant leukotriene B4 (LTB4) which is involved in defense against infection. Leukotriene B4 also activates the transcription factor PPAR alpha, resulting in the activation of genes that terminate inflammatory processes (Yokomizo et al., 1997). Although BLT1 shows homology to other P2Y receptors, it does not function as a purinoreceptor ( Yokomizo et al., 1997). Part of the coding regions of BLTR2 (LS57180) have been duplicated and are part of the 5' UTR noncoding regions of the clusters BLT1 (LS190955) and CIDE-B (LS54843) on chromosome 14.
| Gene Name: | leukotriene B4 receptor |
| Family/Subfamily: | GPCR , Chemoattractant |
| Synonyms: | LTB4R, BLT, BLT1, BLTR, Blt-1, Chemokine receptor-like 1, G protein-coupled receptor 16, GPR16, Leukotriene B4 receptor, Leukotriene B4 receptor 1, G-protein coupled receptor 16, LTBR1, p2Y purinoceptor 7, p2Y7, LTB4-R 1, p2RY7, CMKRL1, LTB4-R1, LTB4R1 |
| Target Sequences: | D89079 BAA20424.1 Q15722 |
Publications (3)
1
Leukotriene B4 signaling through NF-kappaB-dependent BLT1 receptors on vascular smooth muscle cells in atherosclerosis and intimal hyperplasia. Bck M, Bu DX, Brnstrm R, Sheikine Y, Yan ZQ, Hansson GK. Proceedings of the National Academy of Sciences of the United States of America. 2005 102:17501-6. (IHC-Fr; Human)
[PubMed:16293697]
[PMC:PMC1297663]
2
Specialized proresolution mediators in the bladder: annexin-A1 normalizes inflammation and bladder dysfunction during bladder outlet obstruction. Francis M Hughes Jr, Shelby N Harper, Brent D Nosé, Armand Allkanjari, Michael T Zheng, Huixia Jin, J Todd Purves. American journal of physiology. Renal physiology. 2021 October;321:F443-F454. [Full Text Article]
[PubMed:34396790]
[PMC:PMC8560402]
Related Antibodies: LS-A1494.
3
Specialized pro-resolution mediators in the bladder: Receptor expression and recovery of bladder function from cystitis. Francis M Hughes Jr, Armand Allkanjari, Michael R Odom, Huixia Jin, J Todd Purves. Experimental biology and medicine (Maywood, N.J.). 2022 April;247:700-711. [Full Text Article]
[PubMed:35044873]
[PMC:PMC9039492]
Related Antibodies: LS-A1494.
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Neuroscience
Leukotriene B4 Receptor / BLT1 Rabbit anti-Human Polyclonal (Cytoplasmic Domain) Antibody
Rabbit, Mouse, Rat, Hamster, Horse, Human, Monkey
IHC, IHC-Fr, IHC-P
Unconjugated
50 µg/$440
Neuroscience
Fast Shipping
Leukotriene B4 Receptor / BLT1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$440
Fast Shipping
Leukotriene B4 Receptor / BLT1 Rabbit anti-Human Polyclonal (Cytoplasmic Domain) Antibody
Human
IHC, IHC-P
Unconjugated
50 µg/$440
Leukotriene B4 Receptor / BLT1 Mouse anti-Human Monoclonal (PE) Antibody
Human
Flo
PE Conjugated
100 µl/$973
Leukotriene B4 Receptor / BLT1 Rabbit anti-Human Polyclonal (aa250-299) Antibody
Human
WB
Unconjugated
100 µl/$424
Leukotriene B4 Receptor / BLT1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
20 µl/$275; 100 µl/$389
Leukotriene B4 Receptor / BLT1 Rabbit anti-Human Polyclonal Antibody
Human
ICC, IHC, IHC-P, WB
Unconjugated
1 Each/$555
Sandwich
96-Well Strip Plate
Mouse
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$587
Leukotriene B4 Receptor / BLT1 Rabbit anti-Human Polyclonal (aa331-352) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
1 Each/$555
Leukotriene B4 Receptor / BLT1 Rabbit anti-Human Polyclonal Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µg/$460
Leukotriene B4 Receptor / BLT1 Mouse anti-Human Monoclonal (FITC) Antibody
Human
Flo, IHC, IHC-Fr
FITC Conjugated
100 µl/$973
Leukotriene B4 Receptor / BLT1 Rabbit anti-Human Polyclonal (aa331-352) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
100 µl/$737
Sandwich
96-Well Strip Plate
Human
0.78 - 50 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates
1 Plate/$585
Sandwich
96-Well Strip Plate
Human
0.78 - 50 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
Leukotriene B4 Receptor / BLT1 Mouse anti-Human Monoclonal (202/7B1) Antibody
Human
Flo, IF, IHC-Fr
Unconjugated
0.1 mg/$395
Fast Shipping
Leukotriene B4 Receptor / BLT1 Rabbit anti-Human Polyclonal (Cytoplasmic Domain) Antibody
Human
IHC, IHC-P
Unconjugated
50 µg/$460
Leukotriene B4 Receptor / BLT1 Mouse anti-Human Monoclonal Antibody
Human
Flo, IHC, IHC-Fr
Unconjugated
100 µg/$572; 200 µg/$778
Leukotriene B4 Receptor / BLT1 Mouse anti-Human Monoclonal (HRP) Antibody
Human
Flo, IHC
HRP Conjugated
100 µl/$848
Leukotriene B4 Receptor / BLT1 Mouse anti-Human Monoclonal (Biotin) Antibody
Human
Flo, IHC
Biotin Conjugated
100 µl/$848
Leukotriene B4 Receptor / BLT1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human, Monkey
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Leukotriene B4 Receptor / BLT1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC
Unconjugated
100 µg/$351
Leukotriene B4 Receptor / BLT1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
Leukotriene B4 Receptor / BLT1 Mouse anti-Human Monoclonal (FITC) (202/7B1) Antibody
Human
Flo, IHC-Fr
FITC Conjugated
0.1 mg/$510
Leukotriene B4 Receptor / BLT1 Rabbit anti-Human Polyclonal Antibody
Bovine, Human
WB
Unconjugated
100 µl/$289
Leukotriene B4 Receptor / BLT1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
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