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Catalog Number Size Price
LS-A463-50 50 µg (1 mg/ml) $460 
NPFF2 / NPFFR2 Antibody - Brain, Alzheimer's disease, neurofibrillary tangle
NPFF2 / NPFFR2 Antibody - Brain, Cortex, Neurons and glia
NPFF2 / NPFFR2 Antibody - Brain , Medulla
NPFF2 / NPFFR2 Antibody - Brain, Alzheimer's disease, neurofibrillary tangle
NPFF2 / NPFFR2 Antibody - Brain, Cortex, Neurons and glia
NPFF2 / NPFFR2 Antibody - Brain , Medulla
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PathPlus™ Polyclonal Rabbit anti‑Human NPFF2 / NPFFR2 Antibody (N‑Terminus, IHC) LS‑A463

PathPlus™ Polyclonal Rabbit anti‑Human NPFF2 / NPFFR2 Antibody (N‑Terminus, IHC) LS‑A463

Antibody:
NPFF2 / NPFFR2 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Application:
IHC, IHC-P
Reactivity:
Human
Format:
Unconjugated, Unmodified
Price
Catalog Number
$460
LS-A463-50

Toll Free North America
206-374-1102
For Research Use Only

Overview

Antibody:
NPFF2 / NPFFR2 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Application:
IHC, IHC-P
Reactivity:
Human
Format:
Unconjugated, Unmodified

Specifications

Description
Neuropeptide FF 2 Receptor (NPFF2) is a a GPCR with high affinity for NPAF and NPFF, and which is also weakly activated by FMRF-amide (Phe-Met-Arg-Phe-amide) and a variety of related peptides. NPFF2 is expressed in brain regions associated with opiate activity, consistent with the pain-modulating activity of these peptides, and in adipose tissue, suggesting other physiological and pathophysiological activities for FMRF-amide neuropeptides (Elshourbagy et al, 2000). Four isoforms are produced by alternative splicing. References: The UniProt Consortium. Nucleic Acids Res. 47: D506-515 (2019); Nucleic Acids Res. 2016 Jan 4;44(D1):D733-45, PMID:26553804
Target
Human NPFF2 / NPFFR2
Synonyms
NPFFR2 | G protein-coupled receptor 74 | HLWAR77 | G-protein coupled receptor 74 | Neuropeptide FF receptor 2 | Neuropeptide FF 2 | NPFF2 | Neuropeptide FF 2 receptor | NPGPR | GPR74 | NPFF-R2 | NPFF2 receptor | NPGP receptor
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic 20 amino acid peptide from N-Terminus extracellular domain of human NPFFR2. Percent identity with other species by BLAST analysis: Human, Gorilla (100%); Gibbon (95%).
Epitope
N-Terminus
Specificity
Human NPFFR2. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except MFN2 (45%), MFN1 (45%).
Applications
  • IHC
  • IHC - Paraffin (1 - 2 µg/ml)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About NPFF2 / NPFFR2
Q9Y5X5 NM_004885 NP_004876.2

Validation

NPFF2 / NPFFR2 Antibody - Brain, Alzheimer's disease, neurofibrillary tangle
Brain, Alzheimer's disease, neurofibrillary tangle
Brain, Alzheimer's disease, neurofibrillary tangle

NPFF2 / NPFFR2 Antibody - Brain, Cortex, Neurons and glia
Brain, Cortex, Neurons and glia
Brain, Cortex, Neurons and glia

NPFF2 / NPFFR2 Antibody - Brain , Medulla
Brain , Medulla
Brain , Medulla

LSBio Ratings

PathPlus™ NPFF2 / NPFFR2 Antibody (N-Terminus) for IHC LS-A463 has an LSBio Rating of
Publications (4)
Laboratory Validation Score (5)

Publications (1)

Multiple primary cilia modulate the fluid transcytosis in choroid plexus epithelium. Narita K, Kawate T, Kakinuma N, Takeda S. Traffic (Copenhagen, Denmark). 2010 Feb;11:287-301.

Customer Reviews (0)


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Requested From: United States
Date Requested: 6/16/2024