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| Catalog Number | Size | Price |
|---|---|---|
| LS-A387-50 | 50 µg (1 mg/ml) | $440 |
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PathPlus™ Polyclonal Rabbit anti‑Human P2RY1 / P2Y1 Antibody (Extracellular Domain, IHC) LS‑A387
PathPlus™ Polyclonal Rabbit anti‑Human P2RY1 / P2Y1 Antibody (Extracellular Domain, IHC) LS‑A387
Note: This antibody replaces LS-C74015
Antibody:
P2RY1 / P2Y1 Rabbit anti-Human Polyclonal (Extracellular Domain) Antibody
Application:
IHC, IHC-P
Reactivity:
Human, Bat
Format:
Unconjugated, Unmodified
Overview
Antibody:
P2RY1 / P2Y1 Rabbit anti-Human Polyclonal (Extracellular Domain) Antibody
Application:
IHC, IHC-P
Reactivity:
Human, Bat
Format:
Unconjugated, Unmodified
Specifications
Description
Purinergic receptor P2Y, G-protein coupled, 1 (P2RY1) has several receptor subtypes with different pharmacological selectivity for various adenosine and uridine nucleotides. P2RY1 functions as a receptor for extracellular ATP and ADP. In platelets, binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation.
References: The UniProt Consortium. Nucleic Acids Res. 47: D506-515 (2019); Nucleic Acids Res. 2016 Jan 4;44(D1):D733-45, PMID:26553804
Target
Human P2RY1 / P2Y1
Synonyms
P2RY1 | ATP receptor | p2Y1 | p2y1r | Platelet ADP receptor | Purinoceptor p2y1 | Purinergic receptor | p2 purinoceptor subtype Y1 | p2RY1 | p2Y purinoceptor 1 | p2y-1-r | Purinoceptor p2yr1 | p2y1 receptor | P2YR | Purinergic receptor P2Y, G-protein coupled, 1
Host
Rabbit
Reactivity
Human, Bat
(tested or 100% immunogen sequence identity)
Predicted
Monkey, Bovine, Guinea pig, Hamster, Horse, Pig, Rabbit, Chicken (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic 15 amino acid peptide from 2nd extracellular domain of human P2RY1 / P2Y1. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Marmoset, Bat (100%); Monkey, Hamster, Panda, Bovine, Horse, Rabbit, Pig, Guinea pig, Turkey, Chicken, Platypus (93%); Mouse, Rat, Elephant, Xenopus (87%).
Epitope
Extracellular Domain
Specificity
Human P2RY1 / P2Y1. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Applications
- IHC
- IHC - Paraffin (2.5 µg/ml)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About P2RY1 / P2Y1
Validation
Anti-P2RY1 / P2Y1 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-P2RY1 / P2Y1 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Brain, cortex, neuron
Brain, cortex, neuron
Lung, adenocarcinoma
Lung, adenocarcinoma
See More About...
LSBio Ratings
PathPlus™ P2RY1 / P2Y1 Antibody (Extracellular Domain) for IHC LS-A387 has an LSBio Rating of
Laboratory Validation Score (5)
Learn more about The LSBio Ratings Algorithm
Publications (0)
Customer Reviews (0)
Featured Products
Species:
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Hamster, Horse, Rabbit
Applications:
IHC, IHC - Paraffin, ELISA
Species:
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Hamster, Horse, Rabbit
Applications:
IHC, IHC - Paraffin, ELISA
Species:
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Hamster, Rabbit
Applications:
IHC, IHC - Paraffin, ICC
Species:
Human, Rat, Bovine
Applications:
Western blot, ELISA
Species:
Human
Applications:
IHC, IHC - Paraffin, Western blot
Species:
Human
Applications:
IHC, IHC - Paraffin
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 11/22/2024
Date Requested: 11/22/2024
