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P2RY1 / P2Y1

purinergic receptor P2Y, G-protein coupled, 1

P2RY1 / P2Y1 belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor functions as a receptor for extracellular ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation.

Gene Name: purinergic receptor P2Y, G-protein coupled, 1
Family/Subfamily: GPCR , Purinergic
Synonyms: P2RY1, ATP receptor, p2Y1, p2y1r, Platelet ADP receptor, Purinoceptor p2y1, Purinergic receptor, p2 purinoceptor subtype Y1, p2RY1, p2Y purinoceptor 1, p2y-1-r, Purinoceptor p2yr1, p2y1 receptor, P2YR, Purinergic receptor P2Y, G-protein coupled, 1
Target Sequences: NM_002563 NP_002554.1 P47900

Publications (1)

1
ß-Nicotinamide Adenine Dinucleotide (ß-NAD) Inhibits ATP-Dependent IL-1ß Release from Human Monocytic Cells. Hiller SD, Heldmann S, Richter K, Jurastow I, Küllmar M, Hecker A, Wilker S, Fuchs-Moll G, Manzini I, Schmalzing G, Kummer W, Padberg W, McIntosh JM, Damm J, Zakrzewicz A, Grau V. International journal of molecular sciences. 2018 April;19:pii: E1126. (Human) [Full Text Article] [PubMed:29642561] [PMC:PMC5979475] Related Antibodies: LS-C163318.

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Antibodies (39)
Primary (39)
P2RY1 / P2Y1 (39)
Human (38)
Mouse (17)
Rat (20)
Bat (11)
Bovine (8)
Chicken (4)
Chimpanzee (3)
Dog (6)
Gibbon (6)
Guinea pig (7)
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Pig (4)
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IHC (14)
IHC-P (9)
WB (28)
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ELISA (20)
ICC (1)
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Peptide-ELISA (3)
rabbit (34)
mouse (3)
goat (2)
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IgG2a,k (1)
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monoclonal mc (3)
polyclonal pc (36)
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Azide-free (1)
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HRP Conjugated (5)
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Unconjugated (20)
aa231-260 (7)
aa180-229 (4)
aa71-120 (4)
C-Terminus (3)
Extracellular Domain (1)
N-Terminus (1)
aa247-257 (1)
aa345-356 (1)
No (38)
Yes (1)
P2RY1 / P2Y1 Antibody - Brain, cortex, neurons
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Neuroscience
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P2RY1 / P2Y1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Hamster, Horse, Bat, Human, Monkey
ELISA, IHC, IHC-P
Unconjugated
50 µg/$440
P2RY1 / P2Y1 Antibody - Human, Adrenal: Formalin-Fixed Paraffin-Embedded (FFPE)
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P2RY1 / P2Y1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Hamster, Bat, Human, Monkey
ICC, IHC, IHC-P
Unconjugated
50 µg/$440
P2RY1 / P2Y1 Antibody - Lung, adenocarcinoma
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Neuroscience
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P2RY1 / P2Y1 Rabbit anti-Human Polyclonal (Extracellular Domain) Antibody
Bat, Human
IHC, IHC-P
Unconjugated
50 µg/$440
P2RY1 / P2Y1 Antibody - Anti-P2Y1 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 2.5-5 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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P2RY1 / P2Y1 Rabbit anti-Human Polyclonal (aa71-120) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
P2RY1 / P2Y1 Antibody - Anti-P2Y1 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 2.5-5 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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P2RY1 / P2Y1 Rabbit anti-Human Polyclonal (aa71-120) (HRP) Antibody
Chicken, Bovine, Rabbit, Mouse, Dog, Guinea pig, Pig, Horse, Bat, Rat, Hamster, Chimpanzee, Gibbon, Human, Monkey
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
P2RY1 / P2Y1 Antibody - Anti-P2Y1 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 2.5-5 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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P2RY1 / P2Y1 Rabbit anti-Human Polyclonal (aa71-120) (Biotin) Antibody
Chicken, Bovine, Rabbit, Mouse, Dog, Guinea pig, Pig, Horse, Bat, Rat, Hamster, Chimpanzee, Gibbon, Human, Monkey
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
P2RY1 / P2Y1 Antibody - Anti-P2Y1 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 2.5-5 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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P2RY1 / P2Y1 Rabbit anti-Human Polyclonal (aa71-120) (FITC) Antibody
Chicken, Bovine, Rabbit, Mouse, Dog, Guinea pig, Pig, Horse, Bat, Rat, Hamster, Chimpanzee, Gibbon, Human, Monkey
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
P2RY1 / P2Y1 Antibody - P2RY1 Antibody western blot of NCI-H292 cell line lysates (35 ug/lane). The P2RY1 antibody detected the P2RY1 protein (arrow).
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P2RY1 / P2Y1 Rabbit anti-Human Polyclonal (aa231-260) Antibody
Human
WB
Unconjugated
400 µl/$393
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P2RY1 / P2Y1 Mouse anti-Human Monoclonal (4G5D6) Antibody
Human
ELISA, Flo, IHC, WB
Unconjugated
100 µl/$459
P2RY1 / P2Y1 Antibody - Western blot analysis of extracts of various cells.
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P2RY1 / P2Y1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
P2RY1 / P2Y1 Antibody - Anti-P2RY1 / P2Y1 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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P2RY1 / P2Y1 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
IHC, IHC-P
Unconjugated
50 µg/$460
P2RY1 / P2Y1 Antibody - Immunofluorescence of monoclonal antibody to P2RY1 on HeLa cell . [antibody concentration 10 ug/ml]
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P2RY1 / P2Y1 Mouse anti-Human Monoclonal (4C2) Antibody
Human
ELISA, IF, WB
Unconjugated
50 µg/$423
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P2RY1 / P2Y1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Bovine, Rat, Human
ELISA, WB
Unconjugated
100 µg/$740
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P2RY1 / P2Y1 Mouse anti-Human Monoclonal (4G5B7) Antibody
Human
ELISA, Flo, IHC, WB
Unconjugated
100 µl/$459
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P2RY1 / P2Y1 Goat anti-Human Polyclonal (aa345-356) Antibody
Rabbit, Dog, Guinea pig, Bovine, Bat, Human, Monkey
Peptide-ELISA
Unconjugated
100 µg/$384
P2RY1 / P2Y1 Antibody - P2RY1 / P2Y1 antibody Western blot of Rat Liver lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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P2RY1 / P2Y1 Rabbit anti-Rat Polyclonal (aa180-229) Antibody
Rat
WB
Unconjugated
100 µl/$424
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P2RY1 / P2Y1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$341
P2RY1 / P2Y1 Antibody - Immunohistochemistry image of paraffin-embedded human liver cancer at a dilution of 1:100
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P2RY1 / P2Y1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
P2RY1 / P2Y1 Antibody - Immunohistochemistry of paraffin-embedded Human esophagus cancer using P2RY1 Polyclonal Antibody at dilution of 1:50.
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P2RY1 / P2Y1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
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P2RY1 / P2Y1 Rabbit anti-Human Polyclonal (aa231-260) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
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P2RY1 / P2Y1 Rabbit anti-Human Polyclonal (aa231-260) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
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P2RY1 / P2Y1 Rabbit anti-Human Polyclonal (aa231-260) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
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P2RY1 / P2Y1 Rabbit anti-Human Polyclonal (aa231-260) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
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P2RY1 / P2Y1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
P2RY1 / P2Y1 Antibody - Western blot analysis of P2RY1 using COLO205 whole cells lysates
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P2RY1 / P2Y1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).