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| Catalog Number | Size | Price |
|---|---|---|
| LS-B16216-0.05 | 0.05 ml | $460 |
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PathPlus™ Monoclonal Mouse anti‑Human TFE3 Antibody (Concentrated, IHC, WB) LS‑B16216
PathPlus™ Monoclonal Mouse anti‑Human TFE3 Antibody (Concentrated, IHC, WB) LS‑B16216
Note: This antibody replaces LS-C757398
Antibody:
TFE3 Mouse anti-Human Monoclonal (Concentrated) Antibody
Application:
IHC-P, WB, ELISA
Reactivity:
Human
Format:
Unconjugated, Concentrated
Other formats:
Toll Free North America
(800) 227-6666
(800) 227-6666For Research Use Only
Overview
Antibody:
TFE3 Mouse anti-Human Monoclonal (Concentrated) Antibody
Application:
IHC-P, WB, ELISA
Reactivity:
Human
Format:
Unconjugated, Concentrated
Other formats:
Specifications
Description
TFE3 (Transcription factor binding to IGHM enhancer 3) is a nuclear protein that promotes the expression of genes downstream to TGF-beta signaling. Chromosomal translocations between this gene (located on Xp11.2) and other genes promote growth and proliferation, and oncogenic activation. Translocation or overexpression of this gene has been implicated in renal cell carcinoma, lung adenocarcinoma, alveolar soft-part sarcoma, papillary thyroid carcinoma, melanoma, and mesotheliomas. It is expressed in a wide variety of tissues, and is nuclear in localization.
References: AmJSurgPathol 2009 33:1894; Histopath 1993, 23:439
Target
Human TFE3
Synonyms
TFE3 | BHLHe33 | Transcription factor E3 | RCCX1 | TFEA | RCCP2
Host
Mouse
Reactivity
Human
(tested or 100% immunogen sequence identity)
Clonality
IgG1
Monoclonal
Conjugations
Unconjugated
Purification
Protein A/G purified
Modifications
Concentrated.
Also available Ready-to-Use.
Immunogen
Recombinant human TFE3.
Applications
- IHC - Paraffin (1:100 - 1:200)
- Western blot (1:100 - 1:200)
- ELISA (1:100 - 1:200)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Usage
Dilute antibody to its recommended working dilution using the same buffer defined in the Presentation. Manual IHC Protocol: 1) Perform Heat-Induced Epitope Retrieval at pH 9 for 10 to 30 minutes. 2) Block in peroxidase blocking solution for 5 minutes at room temperature. (Not required if using Alkaline Phosphatase System) 3) Dilute antibody 1:100-1:200 before applying. Incubate antibody for 10 to 30 minutes at room temperature. 4) Add secondary antibody and incubate for 20 to 30 minutes at room temperature. 5) Add DAB or Fast Red and incubate for 5 to 10 minutes at room temperature. 6) Counterstain with hematoxylin for 0.5 to 5 minutes, depending on the hematoxylin used. Rinse with distilled water and blueing solution for 30 seconds. Dehydrate and apply coverslip.
Presentation
Tris, pH 7.3-7.7, 1% BSA, <0.1% Sodium Azide
Storage
Store at 2°C to 8°C. Do not freeze.
Restrictions
For research use only. Intended for use by laboratory professionals.
About TFE3
Validation
Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Uterus: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Uterus: Formalin-Fixed, Paraffin-Embedded (FFPE)
See More About...
LSBio Ratings
PathPlus™ TFE3 Antibody (Concentrated) for IHC, WB/Western, ELISA LS-B16216 has an LSBio Rating of
Laboratory Validation Score (5)
Learn more about The LSBio Ratings Algorithm
Publications (0)
Customer Reviews (0)
Featured Products
Species:
Human, Mouse, Rat, Bovine, Dog, Pig
Applications:
IHC, IHC - Paraffin, ICC, Immunofluorescence, Western blot
Species:
Human
Applications:
IHC - Paraffin, Western blot
Species:
Human, Mouse
Applications:
IHC, IHC - Paraffin, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Species:
Human, Mouse, Rat, Bovine, Dog, Pig
Applications:
IHC, IHC - Paraffin, ICC, Immunofluorescence, Western blot
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 11/3/2024
Date Requested: 11/3/2024
