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| Catalog Number | Size | Price |
|---|---|---|
| LS-B16301-100 | 100 µg (200 µg/ml) | $525 |
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2 of 2
PathPlus™ Recombinant Monoclonal Rabbit anti‑Human TFF1 / pS2 Antibody (clone TFF1/2969R, aa50‑100, IHC) LS‑B16301
PathPlus™ Recombinant Monoclonal Rabbit anti‑Human TFF1 / pS2 Antibody (clone TFF1/2969R, aa50‑100, IHC) LS‑B16301
Note: This antibody replaces LS-C751378
Antibody:
TFF1 / pS2 Rabbit anti-Human Recombinant Monoclonal (aa50-100) (TFF1/2969R) Antibody
Application:
IHC-P
Reactivity:
Human
Format:
Unconjugated, Unmodified
Other formats:
Toll Free North America
(800) 227-6666
(800) 227-6666For Research Use Only
Overview
Antibody:
TFF1 / pS2 Rabbit anti-Human Recombinant Monoclonal (aa50-100) (TFF1/2969R) Antibody
Application:
IHC-P
Reactivity:
Human
Format:
Unconjugated, Unmodified
Other formats:
Specifications
Description
TFF1 (trefoil factor 1) is a mucin-associated secreted peptide of gastric mucous cells and plays an essential role in mucosal protection and repair. TFF1 is upregulated in injury, and the secreted peptide plays a role at the epithelial-mesenchymal interface in triggering repair. TFF1 is expressed in a wide variety of carcinomas including colon, lung, pancreas, prostate and breast, and is thought to enhance neoplastic progression through stimulation of cell proliferation, invasion and angiogenesis. In normal tissues, it is expressed in normal stomach epithelium and goblet cells of the GI tract.
References: Endocrinology 150(10):4473; Front Cell Infect Microbiol 2017.00434; Int J Mol Sci 2018 19(7):2018
Target
Human TFF1 / pS2
Synonyms
TFF1 | BCEI | D21S21 | HPS2 | PNR-2 | Polypeptide P1.A | Protein pS2 | PS2 | HP1.A | Trefoil factor 1
Host
Rabbit
Reactivity
Human
(tested or 100% immunogen sequence identity)
Clonality
IgG
Recombinant Monoclonal
Clone
TFF1/2969R
Conjugations
Unconjugated
Purification
Protein A/G purified
Modifications
Unmodified.
Also available Azide-free, Carrier-free.
Immunogen
Synthetic peptide corresponding to the C-Terminus of human TFF1 / pS2.
Epitope
aa50-100
Specificity
This antibody recognizes a 6.5 kDa polypeptide identified as TFF1 / pS2 estrogen-regulated protein.
Applications
- IHC - Paraffin (1:100)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Usage
Immunohistology (Formalin-fixed - 0.5-1.0 ug/ml for 30 minutes at RT - Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes.) Optimal dilution for a specific application should be determined.
Presentation
10 mM PBS, 0.05% BSA, 0.05% Sodium Azide
Storage
Store at 2°C to 8°C for up to 2 years.
Restrictions
For research use only. Intended for use by laboratory professionals.
About TFF1 / pS2
Validation
Human Foveolar Epithelium: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Foveolar Epithelium: Formalin-Fixed, Paraffin-Embedded (FFPE)
See More About...
LSBio Ratings
PathPlus™ TFF1 / pS2 Antibody (aa50-100, clone TFF1/2969R) for IHC LS-B16301 has an LSBio Rating of
Laboratory Validation Score (5)
Learn more about The LSBio Ratings Algorithm
Publications (0)
Customer Reviews (0)
Featured Products
Species:
Human, Rat
Applications:
IHC, IHC - Paraffin, Western blot
Species:
Human
Applications:
IHC, IHC - Paraffin, ELISA
Species:
Human, Rat
Applications:
IHC, IHC - Paraffin, Western blot
Species:
Human
Applications:
IHC, IHC - Paraffin, ICC, Immunofluorescence, Western blot
Species:
Mouse, Monkey, Rat
Applications:
IHC, IHC - Paraffin, Western blot
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 11/22/2024
Date Requested: 11/22/2024
