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| Catalog Number | Size | Price |
|---|---|---|
| LS-G137722-25 | 25 µg (0.2 mg/ml) | $344 |
Human HMG1 / HMGB1 Protein (Recombinant) (Met1-Glu215) - LS-G137722
Human HMG1 / HMGB1 Protein (Recombinant) (Met1-Glu215) - LS-G137722
Description:
HMG1 / HMGB1 Protein LS-G137722 is a Recombinant Human HMG1 / HMGB1 produced in HEK 293 Cells Met1 - Glu215 (Accession# NM_002128). It is biologically active and is low in endotoxin; Less than 0.01 ng/µg (determined by LAL method). For Research Use Only
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(800) 227-6666
(800) 227-6666For Research Use Only
Overview
Description:
HMG1 / HMGB1 Protein LS-G137722 is a Recombinant Human HMG1 / HMGB1 produced in HEK 293 Cells Met1 - Glu215 (Accession# NM_002128). It is biologically active and is low in endotoxin; Less than 0.01 ng/µg (determined by LAL method). For Research Use Only
Specifications
Type
Recombinant Protein
Target
HMG1 / HMGB1
Synonyms
HMGB1 | Amphoterin | High mobility group protein B1 | High mobility group box 1 | High mobility group protein 1 | HMG1 | HMG3 | SBP-1 | High-mobility group box 1 | HMG-1
Species
Human
Modifications
Carrier-free
Conjugations
Unconjugated
Region
Met1 - Glu215 (Accession# NM_002128)
Predicted Molecular Weight
The 215 amino acid recombinant protein has a predicted molecular mass of approximately 24.8 kD. The DTT-reduced and non-reduced protein migrate at approximately 38 and 40 kD respectively by SDS-PAGE. The predicted N-terminal amino acid is Met
Expression System
HEK 293 Cells
Source Species
Human
Purification
Greater than 95% by SDS-PAGE
Usage Summary
Stock solutions can also be prepared at 50 - 100 µg/mL in sterile buffer (PBS, HPBS, DPBS, or EBSS) containing carrier protein such as 0.2 - 1% BSA or HSA.
Bio-Activity
ED50 of 3.0 - 15 µg/ml, as determined by induction of TNF-α in RAW 264.7 monocyte/macrophage mouse cells.
Endotoxin
Less than 0.01 ng/µg (determined by LAL method).
Presentation
0.22 µm filtered protein solution in PBS, pH 7.2
Storage
Store unopened at 2°C to 8°C for up to 1 month, at -20°C for up to 6 months, or at -70°C for up to 1 year. Store diluted at -20°C to -70°C. Avoid freeze/thaw cycles. For maximum results, quick spin vial prior to opening.
Restrictions
For research use only. Intended for use by laboratory professionals.
About HMG1 / HMGB1
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Functional Assay
Human HMGB1 induces TNF-α in RAW 264.7 monocyte/macrophage mouse cells in a dose dependent manner.
Functional Assay
Human HMGB1 induces TNF-α in RAW 264.7 monocyte/macrophage mouse cells in a dose dependent manner.
Functional Assay
Human HMGB1 induces TNF-α in RAW 264.7 monocyte/macrophage mouse cells in a dose dependent manner.
Functional Assay
Human HMGB1 induces TNF-α in RAW 264.7 monocyte/macrophage mouse cells in a dose dependent manner.
Popular HMG1 / HMGB1 Proteins
Source:
E. coli
Tag:
His, N-Terminal
Source:
E. coli
Tag:
His, N-Terminal
Source:
E. coli
Tag:
6His, C-terminus
Source:
Hamster-Chinese
Tag:
Human IgG1 Fc
Source:
Human
Tag:
His,C-terminus
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 12/22/2024
Date Requested: 12/22/2024
