ADAM17 / TACE

ADAM metallopeptidase domain 17

Tumor-necrosis factor-a is a proinflammatory cytokine and contributes to a variety of inflammatory disease responses and programmed cell death. TNF-a is synthesized as a 26K type II membrane-bound precursor that is cleaved by a convertase to generate secreted 17K mature TNF-a. TNF-a converting enzyme (TACE) protein was recently purified and the human and mouse TACE cDNAs were cloned by several groups separately. TACE is a membrane-bound metalloprotease-disintegrin in the family of mammalian ADAM (for a disintegrin and metalloprotease). TACE also processes other cell surface proteins, including TNF receptor, TGFa, the L-selectin adhesion molecule, and alpha-cleavage of amyloid protein precursor (APP). TACE mRNA is expressed in a variety of human and murine tissues. TACE was selected as one of the few targets in cytokine activation by the Eighth International Conference of the Inflammation Research Association. ADAM17 is a Metallopeptidase M12B type protease.

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Antibodies (87)

ELISA Kits (11)

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ADAM17 / TACE (101)

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IHC-plus™ ADAM17 / TACE Antibody (clone 1F6) LS-B4426

(5.0) Rating

(1) Publication(s)

Antibody:

ADAM17 / TACE Mouse anti-Human Monoclonal (1F6) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, PLA, WB

Format:

Unconjugated

Price:

50 µg/$440

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IHC-plus™ ADAM17 / TACE Antibody (C-Terminus) LS-B1821

(4.0) Rating

Antibody:

ADAM17 / TACE Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$460

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ADAM17 / TACE Antibody LS-C263

Antibody:

ADAM17 / TACE Rabbit anti-Human Polyclonal Antibody

Reactivity:

Rat, Human

Applications:

ELISA, ICC, IF, WB

Format:

Unconjugated

Price:

0.1 mg/$460

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ADAM17 / TACE Antibody (phospho-Thr735) LS-C198591

Antibody:

ADAM17 / TACE Rabbit anti-Human Polyclonal (pThr735) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

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IHC-plus™ ADAM17 / TACE Antibody (C-Terminus) LS-B4437

(4.0) Rating

Antibody:

ADAM17 / TACE Goat anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µg/$485

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Rat ADAM17 / TACE (Sandwich ELISA) ELISA Kit - LS-F22349

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Rat

Range:

0.31 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$586

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Human ADAM17 / TACE (Sandwich ELISA) ELISA Kit - LS-F23826

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

62.5 - 4000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Serum

Price:

1 Plate/$651

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ADAM17 / TACE Antibody (aa195-224) LS-C329200

(4.0) Rating

(1) Publication(s)

Antibody:

ADAM17 / TACE Rabbit anti-Human Polyclonal (aa195-224) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, WB

Format:

Unconjugated

Price:

200 µl/$734

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ADAM17 / TACE Antibody (aa195-224, APC) LS-C212599

Antibody:

ADAM17 / TACE Rabbit anti-Human Polyclonal (aa195-224) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, WB

Format:

APC Conjugated

Price:

200 µl/$952

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ADAM17 / TACE Antibody (aa195-224, PE) LS-C212604

Antibody:

ADAM17 / TACE Rabbit anti-Human Polyclonal (aa195-224) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, WB

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• APC
• PE

• Unconjugated
• APC
• PE

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Human ADAM17 / TACE (Sandwich ELISA) ELISA Kit - LS-F6383

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

1 Plate/$641

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Human ADAM17 / TACE Protein (Recombinant 6His, N-terminus) (aa226-473) - LS-G13997

Source:

E. coli

Tag:

6His, N-terminus

Molecular Weight:

29.5 kDa

Price:

10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119

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Mouse ADAM17 / TACE (Sandwich ELISA) ELISA Kit - LS-F16862

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

78 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

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ADAM17 / TACE Antibody (aa1-671) LS-C132358

Antibody:

ADAM17 / TACE Mouse anti-Human Monoclonal (aa1-671) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, WB

Format:

Unconjugated

Price:

100 µg/$860

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ADAM17 / TACE Antibody (670-750 aa) LS-C380935

Antibody:

ADAM17 / TACE Rabbit anti-Human Polyclonal (670-750 aa) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

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ADAM17 / TACE Antibody LS-C331119

Antibody:

ADAM17 / TACE Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

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ADAM17 / TACE Antibody (aa196-245) LS-C121045

Antibody:

ADAM17 / TACE Rabbit anti-Human Polyclonal (aa196-245) Antibody

Reactivity:

Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

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Human ADAM17 / TACE (Sandwich ELISA) ELISA Kit - LS-F188

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

78.15 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$760

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Pig ADAM17 / TACE (Sandwich ELISA) ELISA Kit - LS-F16861

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Pig

Range:

78 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

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ADAM17 / TACE Antibody (C-Terminus) LS-C137039

Antibody:

ADAM17 / TACE Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µl/$332

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ADAM17 / TACE Antibody (670-750 aa) LS-C386303

Antibody:

ADAM17 / TACE Rabbit anti-Human Polyclonal (670-750 aa) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IF

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

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ADAM17 / TACE Antibody (clone 5H4-F10-E11, Preservative Free) LS-C343162

Antibody:

ADAM17 / TACE Mouse anti-Human Monoclonal (Preservative Free) (5H4-F10-E11) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated, Preservative Free

Price:

20 µg/$242; 100 µg/$304; 200 µg/$334; 500 µg/$452

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ADAM17 / TACE Antibody (C-Terminus) LS-C18008

Antibody:

ADAM17 / TACE Rabbit anti-Rat Polyclonal (C-Terminus) Antibody

Reactivity:

Mouse, Rat

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$832

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ADAM17 / TACE Antibody (aa806-824) LS-C312988

Antibody:

ADAM17 / TACE Rabbit anti-Human Polyclonal (aa806-824) Antibody

Reactivity:

Human, Monkey

Applications:

WB

Format:

Unconjugated

Price:

10 µg/$318; 100 µg/$470

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Rat ADAM17 / TACE (Sandwich ELISA) ELISA Kit - LS-F8499

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

1 Plate/$750

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