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| Catalog Number | Size | Price |
|---|---|---|
| LS-B4426-50 | 50 µg (1 mg/ml) | $440 |
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IHC‑plus™ Monoclonal Mouse anti‑Human ADAM17 / TACE Antibody (clone 1F6, IHC, WB) LS‑B4426
IHC‑plus™ Monoclonal Mouse anti‑Human ADAM17 / TACE Antibody (clone 1F6, IHC, WB) LS‑B4426
Note: This antibody replaces LS-C105036
Antibody:
ADAM17 / TACE Mouse anti-Human Monoclonal (1F6) Antibody
Application:
IHC, IHC-P, WB, ELISA, PLA
Reactivity:
Human
Format:
Unconjugated, Unmodified
Toll Free North America
(800) 227-6666
(800) 227-6666For Research Use Only
Overview
Antibody:
ADAM17 / TACE Mouse anti-Human Monoclonal (1F6) Antibody
Application:
IHC, IHC-P, WB, ELISA, PLA
Reactivity:
Human
Format:
Unconjugated, Unmodified
Specifications
Description
TACE antibody LS-B4426 is an unconjugated mouse monoclonal antibody to human TACE (ADAM17). Validated for ELISA, IHC, PLA and WB. Tested on 20 paraffin-embedded human tissues. Cited in 1 publication.
Target
Human ADAM17 / TACE
Synonyms
ADAM17 | CD156B | CD156b antigen | CSVP | ADAM 17 | NISBD | TNF-alpha converting enzyme | TNF-alpha convertase | TNF-alpha-converting enzyme | Snake venom-like protease | TACE
Host
Mouse
Reactivity
Human
(tested or 100% immunogen sequence identity)
Clonality
IgG2b,k
Monoclonal
Clone
1F6
Conjugations
Unconjugated
Purification
Purified from ascites by Protein A
Modifications
Unmodified
Immunogen
ADAM17 (NP_003174, 215 aa ~ 315 aa) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Applications
- IHC
- IHC - Paraffin (5 µg/ml)
- Western blot (1:500 - 1:1000)
- ELISA
- Proximity Ligation Assay
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Usage
Western blot performed with the recombinant protein used as the immunogen. In situ Proximity Ligation Assay (Cell).
Presentation
PBS, pH 7.4
Storage
Store at -20°C. Aliquot to avoid freeze/thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About ADAM17 / TACE
Validation
Anti-ADAM17 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Anti-ADAM17 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Anti-ADAM17 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Anti-ADAM17 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
See More About...
LSBio Ratings
IHC-plus™ ADAM17 / TACE Antibody (clone 1F6) for IHC, WB/Western, ELISA LS-B4426 has an LSBio Rating of
Publications (4)
Laboratory Validation Score (4)
Learn more about The LSBio Ratings Algorithm
Publications (1)
ADAM10 and ADAM17 cleave PD-L1 to mediate PD-(L)1 inhibitor resistance. Jacob J Orme, Khalid A Jazieh, Tiancheng Xie, Susan Harrington, Xin Liu, Matthew Ball, Benjamin Madden, M Cristine Charlesworth, Tariq U Azam, Fabrice Lucien, Bharath Wootla, Yanli Li, Jose Caetano Villasboas, Aaron S Mansfield, Roxana S Dronca, Haidong Dong. Oncoimmunology. 2020 May;9:1744980.
Customer Reviews (0)
Featured Products
Species:
Human, Mouse, Rat
Applications:
Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Species:
Human, Rat
Applications:
ICC, Immunofluorescence, Western blot, ELISA
Species:
Human
Applications:
IHC, IHC - Paraffin, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Species:
Human
Applications:
Western blot, Flow Cytometry, ELISA
Species:
Human
Applications:
Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 11/3/2024
Date Requested: 11/3/2024
