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ALDOA / Aldolase A

aldolase A, fructose-bisphosphate

ALDOA / Aldolase A, Aldolase A (fructose-bisphosphate aldolase), is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Three aldolase isozymes (A, B, and C), encoded by three different genes, are differentially expressed during development. Aldolase A is found in the developing embryo and is produced in even greater amounts in adult muscle. Aldolase A expression is repressed in adult liver, kidney and intestine and similar to aldolase C levels in brain and other nervous tissue. Aldolase A deficiency has been associated with myopathy and hemolytic anemia. Alternative splicing and alternative promoter usage results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 3 and 10.

Gene Name: aldolase A, fructose-bisphosphate
Synonyms: ALDOA, ALDA, Aldolase, GSD12, Muscle-type aldolase, Lung cancer antigen NY-LU-1
Target Sequences: NM_000034 NP_000025.1 P04075

Publications (2)

1
The deubiquitinase JOSD2 is a positive regulator of glucose metabolism. Lyudmila Krassikova , Boxi Zhang , Divya Nagarajan, André Lima Queiroz, Merve Kacal, Evangelos Samakidis, Helin Vakifahmetoglu-Norberg, Erik Norberg. Cell death and differentiation. 2020 October; [Full Text Article] [PubMed:33082514] [PMC:PMC7937685] Related Antibodies: LS-B1461.
2
Proteomic profiling of osteosarcoma cells identifies ALDOA and SULT1A3 as negative survival markers of human osteosarcoma. Chen X, Yang TT, Zhou Y, Wang W, Qiu XC, Gao J, Li CX, Long H, Ma BA, Ma Q, Zhang XZ, Yang LJ, Fan QY. Molecular carcinogenesis. 2014 Feb;53:138-44. [Full Text Article] [PubMed:22949271] Related Antibodies: LS-B1461.

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ELISA Kits (19)
Cell-Based (1)
Competitive EIA (3)
Custom (2)
Sandwich (12)
Sandwich CLIA (1)
ALDOA / Aldolase A (19)
Human (8)
Mouse (3)
Rat (4)
Chicken (1)
Guinea pig (1)
Monkey (1)
Porcine (1)
Rabbit (1)
Sheep (1)
12 x 8-Well Microstrips (1)
96-Well Microplate (2)
96-Well Strip Plate (16)
No (19)
Adherent Cell Cultures (1)
Cell Supernatant (1)
Plasma (10)
Serum (10)
Tissue Homogenates (3)
ALDOA / Aldolase A ELISA Kit
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Sandwich
96-Well Microplate
Human
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$610
ALDOA / Aldolase A ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$818
ALDOA / Aldolase A ELISA Kit
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Sandwich
96-Well Strip Plate
Human
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$764
ALDOA / Aldolase A ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
31.2 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
ALDOA / Aldolase A ELISA Kit
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Custom
96-Well Strip Plate
Human
Colorimetric - 450nm (TMB)
1 Plate/$783
ALDOA / Aldolase A ELISA Kit
Select
Custom
96-Well Strip Plate
Rat
Colorimetric - 450nm (TMB)
1 Plate/$783
ALDOA / Aldolase A ELISA Kit
Select
Sandwich CLIA
12 x 8-Well Microstrips
Human
15.625 - 1000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$728
ALDOA / Aldolase A ELISA Kit
Select
Cell-Based
96-Well Microplate
Mouse, Human, Rat
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
1 Plate/$618
ALDOA / Aldolase A ELISA Kit
Select
Sandwich
96-Well Strip Plate
Guinea pig
3.125 - 200 pg/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
ALDOA / Aldolase A ELISA Kit
Select
Sandwich
96-Well Strip Plate
Chicken
3.125 - 200 pg/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
ALDOA / Aldolase A ELISA Kit
Select
Sandwich
96-Well Strip Plate
Porcine
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
ALDOA / Aldolase A ELISA Kit
Select
Sandwich
96-Well Strip Plate
Monkey
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
ALDOA / Aldolase A ELISA Kit
Select
Sandwich
96-Well Strip Plate
Sheep
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
1 Plate/$760
ALDOA / Aldolase A ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rabbit
2.5 - 160 pg/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
ALDOA / Aldolase A ELISA Kit
Select
Competitive EIA
96-Well Strip Plate
Rat
0.5 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$913
ALDOA / Aldolase A ELISA Kit
Select
Competitive EIA
96-Well Strip Plate
Human
2.5 - 50 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$913
ALDOA / Aldolase A ELISA Kit
Select
Competitive EIA
96-Well Strip Plate
Mouse
2.5 - 50 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$913
ALDOA / Aldolase A ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
ALDOA / Aldolase A ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.31 - 20 ng/ml
Colorimetric - 450nm (TMB)
Cell Supernatant, Plasma, Serum
1 Plate/$598
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).