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ALDOA / Aldolase A

aldolase A, fructose-bisphosphate

ALDOA / Aldolase A, Aldolase A (fructose-bisphosphate aldolase), is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Three aldolase isozymes (A, B, and C), encoded by three different genes, are differentially expressed during development. Aldolase A is found in the developing embryo and is produced in even greater amounts in adult muscle. Aldolase A expression is repressed in adult liver, kidney and intestine and similar to aldolase C levels in brain and other nervous tissue. Aldolase A deficiency has been associated with myopathy and hemolytic anemia. Alternative splicing and alternative promoter usage results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 3 and 10.

Gene Name: aldolase A, fructose-bisphosphate
Synonyms: ALDOA, ALDA, Aldolase, GSD12, Muscle-type aldolase, Lung cancer antigen NY-LU-1
Target Sequences: NM_000034 NP_000025.1 P04075

Publications (2)

1
The deubiquitinase JOSD2 is a positive regulator of glucose metabolism. Lyudmila Krassikova , Boxi Zhang , Divya Nagarajan, André Lima Queiroz, Merve Kacal, Evangelos Samakidis, Helin Vakifahmetoglu-Norberg, Erik Norberg. Cell death and differentiation. 2020 October; [Full Text Article] [PubMed:33082514] [PMC:PMC7937685] Related Antibodies: LS-B1461.
2
Proteomic profiling of osteosarcoma cells identifies ALDOA and SULT1A3 as negative survival markers of human osteosarcoma. Chen X, Yang TT, Zhou Y, Wang W, Qiu XC, Gao J, Li CX, Long H, Ma BA, Ma Q, Zhang XZ, Yang LJ, Fan QY. Molecular carcinogenesis. 2014 Feb;53:138-44. [Full Text Article] [PubMed:22949271] Related Antibodies: LS-B1461.

☰ Filters
Products
Proteins (18)
Over-Expression Lysate (8)
Recombinant (10)
ALDOA / Aldolase A (18)
No (18)
6His, C-terminus (2)
GST (1)
GST, N-terminus (1)
His (1)
His-T7 (1)
Myc-DDK (Flag) (12)
Human (14)
293T Cells (4)
E. coli (4)
HEK 293 Cells (8)
Wheat Germ Extract (2)
Purified (1)
Low endotoxin level (2)
Biologically active (1)
ALDOA / Aldolase A Protein
Select
E. coli
His
Biologically active
100 µg/$342; 500 µg/$641; 20 µg/$254
ALDOA / Aldolase A Protein - Recombinant Aldolase A, Fructose Bisphosphate By SDS-PAGE
Select
E. coli
His-T7
31.6 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
Select
E. coli
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
40.48kD
10 µg/$288; 50 µg/$442; 500 µg/$1,585; 1 mg/$2,157
Select
293T Cells
Myc-DDK (Flag)
39.2 kDa
20 µg/$150
ALDOA / Aldolase A Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
39.2 kDa
20 µg/$150
ALDOA / Aldolase A Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
39.2 kDa
20 µg/$150
ALDOA / Aldolase A Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
39.2 kDa
20 µg/$150
ALDOA / Aldolase A Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
Select
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
ALDOA / Aldolase A Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
39.2 kDa
100 µg/$494
ALDOA / Aldolase A Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
39.2 kDa
100 µg/$494
ALDOA / Aldolase A Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
39.2 kDa
100 µg/$494
ALDOA / Aldolase A Protein - Purified recombinant protein ALDOA was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
39.2 kDa
20 µg/$1,107
ALDOA / Aldolase A Protein - Purified recombinant protein ALDOA was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
39.2 kDa
20 µg/$1,107
ALDOA / Aldolase A Protein - Purified recombinant protein ALDOA was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
39.2 kDa
20 µg/$1,107
ALDOA / Aldolase A Protein - Purified recombinant protein ALDOA was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
39.2 kDa
20 µg/$1,107
ALDOA / Aldolase A Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
39.2 kDa
100 µg/$494
Select
E. coli
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
40.5 kDa
10 µg/$376; 50 µg/$526
ALDOA / Aldolase A Protein - 12.5% SDS-PAGE of human ALDOA stained with Coomassie Blue
Select
Wheat Germ Extract
GST
65.78 kDa
10 µg/$479; 25 µg/$670
Viewing 1-18 of 18 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).