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Alpha-Fetoprotein

AFP / Alpha Fetoprotein is alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.

Gene Name: Alpha-Fetoprotein
Synonyms: AFP, Alpha-1-fetoprotein, Alpha-fetoprotein, HPAFP, Alpha-fetoglobulin, FETA
Target Sequences: NM_001134 NP_001125.1 P02771

Publications (1)

1
Maternal hepatocytes heterogeneously and dynamically exhibit developmental phenotypes partially via yes-associated protein 1 during pregnancy. Shashank Manohar Nambiar, Joonyong Lee, Jennifer Abla Yanum, Veronica Garcia, Huaizhou Jiang, Guoli Dai. American journal of physiology. Gastrointestinal and liver physiology. 2023 January;324:G38-G50. [Full Text Article] [PubMed:36283963] [PMC:PMC9799147] Related Antibodies: LS-C123534.

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Antibodies (340)
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Alpha-Fetoprotein (340)
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Alpha-Fetoprotein Goat anti-Mouse Polyclonal (aa19-605) Antibody
Mouse
ELISA, WB
Unconjugated
100 µg/$930
Alpha-Fetoprotein Antibody - Anti-Alpha-Fetoprotein antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml.
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Alpha-Fetoprotein Rabbit anti-Human Polyclonal (Internal) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$460
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Alpha-Fetoprotein Rabbit anti-Human Polyclonal Antibody
Human
IHC, IHC-P, WB
Unconjugated
250 µl/$483
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Alpha-Fetoprotein Mouse anti-Human Monoclonal (Biotin) (1301) Antibody
Human
ELISA
Biotin Conjugated
100 µl/$558
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Alpha-Fetoprotein Rabbit anti-Human Polyclonal Antibody
Human
ID
Unconjugated
1 ml/$351
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Alpha-Fetoprotein Rabbit anti-Human Polyclonal (FITC) Antibody
Human
IF
FITC Conjugated
1 ml/$438
Alpha-Fetoprotein Antibody - Anti-Alpha-Fetoprotein antibody IHC of human liver. human. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.
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Alpha-Fetoprotein Mouse anti-Human Monoclonal (6E6) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$460
Alpha-Fetoprotein Antibody - Immunohistochemistry of paraffin-embedded Human liver cancer using AFP Polyclonal Antibody at dilution of 1:60.
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Alpha-Fetoprotein Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
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Alpha-Fetoprotein Mouse anti-Human Monoclonal (C3) Antibody
Mouse, Dog, Bovine, Rat, Pig, Cat, Human
IHC, IHC-P
Unconjugated
0.1 ml/$275; 0.5 ml/$355; 1 ml/$448
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Alpha-Fetoprotein Chicken anti-Human Polyclonal Antibody
Human
ELISA, Flo, ICC, IF, IHC, IP, Neut, RIA, WB
Unconjugated
100 µg/$951
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Alpha-Fetoprotein Mouse anti-Human Monoclonal (4A3) Antibody
Human
ELISA
Unconjugated
0.2 mg/$486
Alpha-Fetoprotein Antibody - Human Liver, Hepatocellular Carcinoma: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Cancer Pathology
Cancer
Alpha-Fetoprotein Mouse anti-Human Monoclonal (OTI2E2) Antibody
Human
Flo, IF, IHC-P, WB
Unconjugated
50 µl/$460
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Alpha-Fetoprotein Mouse anti-Human Monoclonal (C2) Antibody
Mouse, Human
ELISA, IHC, IHC-Fr, WB
Unconjugated
100 µg/$688
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Alpha-Fetoprotein Mouse anti-Human Monoclonal (4A3) Antibody
Human
ELISA
Unconjugated
0.2 mg/$407; 0.5 mg/$487
Alpha-Fetoprotein Antibody - Immunohistochemistry of AFP in rat liver tissue with AFP antibody at 10 µg/mL.
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Alpha-Fetoprotein Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
0.1 mg/$460
Alpha-Fetoprotein Antibody - Anti-Alpha-Fetoprotein antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 20 ug/ml.
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Alpha-Fetoprotein Mouse anti-Human Monoclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$460
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Alpha-Fetoprotein Mouse anti-Human Monoclonal (1305) Antibody
ELISA
Unconjugated
1 mg/$902
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Alpha-Fetoprotein Mouse anti-Human Monoclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
200 µl/$688
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Alpha-Fetoprotein Goat anti-Human Polyclonal (Fab'2) Antibody
Human
ELISA, Flo, ID, IHC, IP, WB
Unconjugated, Fab'2
1 mg/$283
Alpha-Fetoprotein Antibody - Western blot of recombinant AFP / Alpha Fetoprotein.
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Alpha-Fetoprotein Rabbit anti-Pig Polyclonal (aa263-386) (FITC) Antibody
Pig
WB
FITC Conjugated
100 µl/$359; 200 µl/$422; 500 µl/$652; 1 ml/$812; 2 ml/$1,051; 5 ml/$1,853
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Alpha-Fetoprotein Mouse anti-Human Monoclonal Antibody
Human
ELISA, IP, RIA, WB
Unconjugated
500 µg/$657
Alpha-Fetoprotein Antibody - Western blot of recombinant AFP / Alpha Fetoprotein.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Alpha-Fetoprotein Rabbit anti-Human Polyclonal (aa31-171) Antibody
Pig, Human
ICC, IP, WB
Unconjugated
100 µl/$269; 200 µl/$295; 500 µl/$379; 1 ml/$421; 2 ml/$505; 5 ml/$839
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Alpha-Fetoprotein Mouse anti-Human Monoclonal (Concentrated) (MBS-12) Antibody
Human
ELISA, IHC, IHC-Fr
Unconjugated, Concentrated
100 µg/$432
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Alpha-Fetoprotein Mouse anti-Human Monoclonal Antibody
Human
Flo, IHC
Unconjugated
100 µg/$930
Alpha-Fetoprotein Antibody - Western blot of Alpha-Fetoprotein antibody.
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Alpha-Fetoprotein Rabbit anti-Human Polyclonal (aa31-576) Antibody
Human
ICC, IP, WB
Unconjugated
100 µl/$269; 200 µl/$295; 500 µl/$379; 1 ml/$421
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).