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APCS / Serum Amyloid P / SAP

amyloid P component, serum

APCS / Serum Amyloid P / SAP is a glycoprotein, belonging to the pentraxin family of proteins, which has a characteristic pentameric organization. These family members have considerable sequence homology which is thought to be the result of gene duplication. The binding of the encoded protein to proteins in the pathological amyloid cross-beta fold suggests its possible role as a chaperone. This protein is also thought to control the degradation of chromatin. It has been demonstrated that this protein binds to apoptotic cells at an early stage, which raises the possibility that it is involved in dealing with apoptotic cells in vivo.

Gene Name: amyloid P component, serum
Synonyms: APCS, 9.5S alpha-1-glycoprotein, Amyloid P component, serum, Pentaxin-related, PTX2, Serum Amyloid P, Serum amyloid P-component, SAP
Target Sequences: NM_001639 NP_001630.1 P02743

Publications (1)

1
The proteome microenvironment determines the protective effect of preconditioning in cisplatin-induced acute kidney injury. Martin R Späth, Malte P Bartram, Nicolàs Palacio-Escat, K Johanna R Hoyer, Cedric Debes, Fatih Demir, Christina B Schroeter, Amrei M Mandel, Franziska Grundmann, Giuliano Ciarimboli, Andreas Beyer, Jayachandran N Kizhakkedathu, Susanne Brodesser, Heike Göbel, Jan U Becker, Thomas Benzing, Bernhard Schermer, Martin Höhne, Volker Burst, Julio Saez-Rodriguez, Pitter F Huesgen, Roman-Ulrich Müller, Markus M Rinschen. Kidney international. 2019 February;95:333-349. [Full Text Article] [PubMed:30522767] Related Antibodies: LS-B11917.

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APCS / Serum Amyloid P / SAP (89)
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APCS / Serum Amyloid P / SAP Antibody - Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Neuroscience
APCS / Serum Amyloid P / SAP Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
APCS / Serum Amyloid P / SAP Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Neuroscience
APCS / Serum Amyloid P / SAP Mouse anti-Human Monoclonal (7F3) Antibody
Human
ELISA, IHC-P, WB
Unconjugated
50 µg/$460
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APCS / Serum Amyloid P / SAP Mouse anti-Human Monoclonal (5.4A) Antibody
Human
ELISA
Unconjugated
100 µg/$748
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APCS / Serum Amyloid P / SAP Mouse anti-Human Monoclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
100 µl/$990
APCS / Serum Amyloid P / SAP Antibody - APCS antibody ARP41962_T100-NP_001630-APCS(amyloid P component, serum) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human intestine.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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APCS / Serum Amyloid P / SAP Rabbit anti-Human Polyclonal (aa51-100) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$397
APCS / Serum Amyloid P / SAP Antibody - APCS antibody immunohistochemistry of formalin-fixed and paraffin-embedded human hepatocarcinoma followed by peroxidase-conjugated secondary antibody and DAB staining.
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APCS / Serum Amyloid P / SAP Rabbit anti-Human Polyclonal (aa151-178) Antibody
Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
APCS / Serum Amyloid P / SAP Antibody - APCS / Serum Amyloid P / SAP antibody. IHC(P): Mouse Kidney Tissue.
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APCS / Serum Amyloid P / SAP Rabbit anti-Mouse Polyclonal (aa21-224) Antibody
Mouse
ELISA, IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
APCS / Serum Amyloid P / SAP Antibody - Human brain, formalin-fixed, paraffin-embedded.  Antibody at 1:100 following HIER with citrate buffer pH 6.0
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APCS / Serum Amyloid P / SAP Rabbit anti-Human Polyclonal Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$286; 100 µl/$321
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APCS / Serum Amyloid P / SAP Mouse anti-Human Monoclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$860
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APCS / Serum Amyloid P / SAP Mouse anti-Human Monoclonal Antibody
Human
ELISA
Unconjugated
100 µg/$771
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APCS / Serum Amyloid P / SAP Mouse anti-Human Monoclonal (FITC) Antibody
Human
ELISA
FITC Conjugated
100 µl/$1,006
APCS / Serum Amyloid P / SAP Antibody - Anti-APCS mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY APCS.
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APCS / Serum Amyloid P / SAP Mouse anti-Human Monoclonal (OTI1H2) Antibody
Human
IF, WB
Unconjugated
100 µl/$434
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APCS / Serum Amyloid P / SAP Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Mouse, Human
ELISA, WB
Unconjugated
40 µg/$485
APCS / Serum Amyloid P / SAP Antibody - Western blot of recombinant APCS / Serum Amyloid P / SAP.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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APCS / Serum Amyloid P / SAP Rabbit anti-Human Polyclonal (aa20-223) Antibody
Human
WB
Unconjugated
100 µl/$303; 200 µl/$343; 500 µl/$476; 1 ml/$543; 2 ml/$715; 5 ml/$1,182
APCS / Serum Amyloid P / SAP Antibody - Immunohistochemistry - Anti-Serum Amyloid P Picoband antibody
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APCS / Serum Amyloid P / SAP Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
APCS / Serum Amyloid P / SAP Antibody - APCS / Serum Amyloid P / SAP antibody. IHC(P): Rat Liver Tissue.
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APCS / Serum Amyloid P / SAP Rabbit anti-Rat Polyclonal (aa21-228) Antibody
Rat
ELISA, IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
APCS / Serum Amyloid P / SAP Antibody - Immunochemical staining of human APCS in human duodenum with rabbit polyclonal antibody at 1:1000 dilution, formalin-fixed paraffin embedded sections.
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APCS / Serum Amyloid P / SAP Rabbit anti-Human Polyclonal (Preservative Free) Antibody
Human
ICC, IF, IHC-P
Unconjugated, Preservative Free
50 µl/$317; 100 µl/$375; 200 µl/$473
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APCS / Serum Amyloid P / SAP Rabbit anti-Human Polyclonal (aa151-178) Antibody
Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
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APCS / Serum Amyloid P / SAP Rabbit anti-Human Polyclonal (aa151-178) (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
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APCS / Serum Amyloid P / SAP Rabbit anti-Human Polyclonal (aa151-178) (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
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APCS / Serum Amyloid P / SAP Rabbit anti-Human Polyclonal (aa151-178) (APC) Antibody
Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
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APCS / Serum Amyloid P / SAP Rabbit anti-Human Polyclonal (aa151-178) (Azide-free) (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
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APCS / Serum Amyloid P / SAP Rabbit anti-Human Polyclonal (aa151-178) (PE) Antibody
Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
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APCS / Serum Amyloid P / SAP Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$331
APCS / Serum Amyloid P / SAP Antibody - Immunohistochemistry of paraffin-embedded human kidney using antibody at 1:100 dilution.
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APCS / Serum Amyloid P / SAP Rabbit anti-Human Polyclonal (aa1-223) Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$294; 100 µl/$360
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).