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Involved in DNA damage response. Involved in a RAD9A-related damage checkpoint, a pathway that is important in determining whether DNA damage is compatible with cell survival or whether it requires cell elimination by apoptosis. Modulates the RAD9A interaction with BCL2 and thereby induces DNA damages-induced apoptosis.
Gene Name: | ATPase family, AAA domain containing 5 |
Synonyms: | ATAD5, C17orf41, FRAG1, ELG1 |
Target Sequences: | NM_024857 NP_079133.3 Q96QE3 |
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