CASP4 / Caspase 4

caspase 4, apoptosis-related cysteine peptidase

Caspases are a family of cysteine proteases that can be divided into the apoptotic and inflammatory caspase subfamilies. Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens. Members of this subfamily include caspase-1, -4, -5, and -12. Activation of these caspases results in the cleavage and activation of proinflammatory cytokines such as IL-1b and IL-18. Caspase-4 was initially identified as a homologous protein to Caspase-1 and the C. elegans Ced-3 which could induce apoptosis in transfected cells. More recent studies have shown that it can be activated by ER stress and has been suggested to be involved in multiple neuronal pathologies such as Alzheimer's disease. The rodent homolog is known as Caspase 4 and Caspase 11.

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Products

Antibodies (128)

Type

Primary (128)

Target

CASP4 / Caspase 4 (128)

Reactivity

Human (70)

Mouse (55)

Rat (11)

Bovine (24)

Chimpanzee (6)

Cow (24)

Gibbon (6)

Monkey (2)

Application

IHC (25)

IHC-P (11)

WB (123)

Flo (3)

ELISA (19)

ICC (1)

IF (4)

IP (2)

Peptide-ELISA (7)

Host

rabbit (109)

mouse (14)

goat (1)

rat (4)

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IHCPlus (3)

Isotype

IgG (35)

IgG1 (5)

IgG1,k (3)

IgG2a (1)

IgG2a,k (1)

Clonality

monoclonal mc (18)

polyclonal pc (110)

Clone

4B9 (1)

4E11 (1)

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Biotin Conjugated (13)

Carrier-free (2)

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Epitope

aa81-270 (20)

aa290-377 (16)

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40-120 aa, Internal (1)

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Glu124 (1)

aa104-124 (1)

aa118-132 (1)

aa163-197 (1)

aa202-217 (1)

aa337-372 (1)

aa62-111 (1)

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Publications

No (128)

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IHC-plus™ CASP4 / Caspase 4 Antibody LS-B710

(4.0) Rating

Antibody:

CASP4 / Caspase 4 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$545

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CASP4 / Caspase 4 Antibody (40-120 aa, Internal) LS-C380473

Antibody:

CASP4 / Caspase 4 Rabbit anti-Human Polyclonal (40-120 aa, Internal) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

Select

IHC-plus™ CASP4 / Caspase 4 Antibody LS-B3789

(4.0) Rating

Antibody:

CASP4 / Caspase 4 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

0.05 mg/$460

Select

IHC-plus™ CASP4 / Caspase 4 Antibody LS-B3793

(4.0) Rating

Antibody:

CASP4 / Caspase 4 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

0.05 mg/$460

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CASP4 / Caspase 4 Antibody (N-Terminus) LS-C121481

Antibody:

CASP4 / Caspase 4 Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µg/$1,049

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CASP4 / Caspase 4 Antibody (N-Terminus) LS-C121482

Antibody:

CASP4 / Caspase 4 Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µg/$729

Select

CASP4 / Caspase 4 Antibody LS-C816029

Antibody:

CASP4 / Caspase 4 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ICC, IF

Format:

Unconjugated

Price:

100 µl/$412

Select

CASP4 / Caspase 4 Antibody (C-Terminus) LS-C35307

Antibody:

CASP4 / Caspase 4 Rabbit anti-Mouse Polyclonal (C-Terminus) Antibody

Reactivity:

Mouse

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$832

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CASP4 / Caspase 4 Antibody (aa202-217) LS-C35304

Antibody:

CASP4 / Caspase 4 Rabbit anti-Mouse Polyclonal (aa202-217) Antibody

Reactivity:

Mouse, Rat

Applications:

WB

Format:

Unconjugated

Price:

100 µg/$811

Select

CASP4 / Caspase 4 Antibody LS-C498510

Antibody:

CASP4 / Caspase 4 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

Select

CASP4 / Caspase 4 Antibody (aa290-377) LS-C293210

Antibody:

CASP4 / Caspase 4 Rabbit anti-Human Polyclonal (aa290-377) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$303; 200 µl/$343; 500 µl/$476; 1 ml/$543; 2 ml/$715; 5 ml/$1,182

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CASP4 / Caspase 4 Antibody LS-C662763

Antibody:

CASP4 / Caspase 4 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

10 µg/$318; 100 µg/$470

Select

CASP4 / Caspase 4 Antibody (clone 8A5) LS-C344952

Antibody:

CASP4 / Caspase 4 Rat anti-Mouse Monoclonal (8A5) Antibody

Reactivity:

Mouse, Rat

Applications:

ELISA, Flo, IP, WB

Format:

Unconjugated

Price:

100 µg/$435

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CASP4 / Caspase 4 Antibody (clone 4E11) LS-C344797

Antibody:

CASP4 / Caspase 4 Rat anti-Mouse Monoclonal (4E11) Antibody

Reactivity:

Mouse, Rat

Applications:

ELISA, Flo, IP, WB

Format:

Unconjugated

Price:

100 µg/$435

Select

CASP4 / Caspase 4 Antibody LS-C662572

Antibody:

CASP4 / Caspase 4 Rabbit anti-Mouse Polyclonal Antibody

Reactivity:

Mouse

Applications:

ELISA, WB

Format:

Unconjugated

Price:

10 µg/$318; 100 µg/$470

Select

CASP4 / Caspase 4 Antibody (aa104-124) LS-C312648

Antibody:

CASP4 / Caspase 4 Rabbit anti-Human Polyclonal (aa104-124) Antibody

Reactivity:

Human, Monkey

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

10 µg/$318; 100 µg/$470

Select

CASP4 / Caspase 4 Antibody (Internal) LS-C382451

Antibody:

CASP4 / Caspase 4 Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

Select

CASP4 / Caspase 4 Antibody LS-C659550

Antibody:

CASP4 / Caspase 4 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$331

Select

CASP4 / Caspase 4 Antibody LS-C801278

Antibody:

CASP4 / Caspase 4 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Select

CASP4 / Caspase 4 Antibody LS-C35306

Antibody:

CASP4 / Caspase 4 Rat anti-Mouse Monoclonal Antibody

Reactivity:

Mouse, Rat

Applications:

Flo, WB

Format:

Unconjugated

Price:

100 µg/$720

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CASP4 / Caspase 4 Antibody (N-Terminus, Concentrated) LS-C202788

Antibody:

CASP4 / Caspase 4 Rabbit anti-Human Polyclonal (N-Terminus) (Concentrated) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated, Concentrated

Price:

0.1 mg/$734

Select

CASP4 / Caspase 4 Antibody (clone 7G7) LS-C196818

Antibody:

CASP4 / Caspase 4 Mouse anti-Human Monoclonal (7G7) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$423

Select

CASP4 / Caspase 4 Antibody (Glu124) LS-C177726

Antibody:

CASP4 / Caspase 4 Rabbit anti-Human Polyclonal (Glu124) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$321; 100 µl/$403

Select

CASP4 / Caspase 4 Antibody (aa75-124) LS-C291682

Antibody:

CASP4 / Caspase 4 Rabbit anti-Human Polyclonal (aa75-124) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

Select

CASP4 / Caspase 4 Antibody (Internal) LS-C351915

Antibody:

CASP4 / Caspase 4 Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$299

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