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6737 Mowry Ave
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CASP7 / Caspase 7
caspase 7, apoptosis-related cysteine peptidase
Caspases are a family of cysteine proteases that can be divided into the apoptotic and inflammatory caspase subfamilies. Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens. The apoptotic subfamily can be further divided into initiator caspases, which are activated in response to death signals, and executioner caspases, which are activated by the initiator caspases and are responsible for cleavage of cellular substrates that ultimately lead to cell death. Caspase-7 is an executioner caspase that was identified based on its homology with caspases 1 and 3, as well as the C. elegans cell death protein CED-3. Alternative splicing of Caspase-7 mRNA results in the production of 3 distinct isoforms. Caspase-7 activity can be directly inhibited by XIAP expression.
| Gene Name: | caspase 7, apoptosis-related cysteine peptidase |
| Family/Subfamily: | Protease , Cysteine C14 |
| Synonyms: | CASP7, Apoptotic protease Mch-3, Caspase 7, Caspase-7, ICE-LAP3, LICE2, MCH3, ICE-like apoptotic protease 3, CASP-7, CMH-1 |
| Target Sequences: | NM_001227 NP_001218.1 P55210 |
Publications (1)
1
Therapeutic targeting of the survivin pathway in cancer: initiation of mitochondrial apoptosis and suppression of tumor-associated angiogenesis. Blanc-Brude OP, Mesri M, Wall NR, Plescia J, Dohi T, Altieri DC. Clinical cancer research : an official journal of the American Association for Cancer Research. 2003 9:2683-92.
[PubMed:12855648]
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(3)
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CASP7 / Caspase 7
(157)
Reactivity
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(89)
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(59)
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(45)
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(1)
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(3)
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(4)
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(1)
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(3)
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(18)
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(6)
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(9)
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(10)
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(1)
CASP7 / Caspase 7 Mouse anti-Human Monoclonal (7-1-11) Antibody
Rabbit, Mouse, Dog, Sheep, Rat, Hamster, Pig, Human, Monkey
IHC, IHC-P, WB
Unconjugated
50 µg/$440
CASP7 / Caspase 7 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, IHC-P, WB
Unconjugated
0.05 mg/$460
E. coli
His, N-Terminal
19.5 kDa
10 µg/$294; 50 µg/$522; 100 µg/$832; 200 µg/$1,034; 1 mg/$2,192; 500 µg/$1,712; 5 mg/$3,641; 2 mg/$2,383
E. coli
His-T7
15.1 kDa
10 µg/$294; 50 µg/$522; 100 µg/$832; 200 µg/$1,034; 1 mg/$2,192; 500 µg/$1,712; 5 mg/$3,641; 2 mg/$2,383
CASP7 / Caspase 7 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ICC, IF, IHC, IP, WB
Unconjugated
20 µl/$275; 100 µl/$389
CASP7 / Caspase 7 Mouse anti-Human Monoclonal Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
0.1 ml/$460
CASP7 / Caspase 7 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Rat, Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$299
CASP7 / Caspase 7 Mouse anti-Human Monoclonal (10-1-62) Antibody
Mouse, Rat, Hamster, Human, Monkey
IHC, IHC-P, WB
Unconjugated
50 µg/$460
CASP7 / Caspase 7 Mouse anti-Human Monoclonal (25B881.1) Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µg/$460
CASP7 / Caspase 7 Mouse anti-Human Monoclonal (4G2) Antibody
Mouse, Rat, Human
IP, WB
Unconjugated
100 µg/$403
CASP7 / Caspase 7 Mouse anti-Human Monoclonal (4D10B2) Antibody
Human
ELISA, Flo, IHC, WB
Unconjugated
100 µl/$459
CASP7 / Caspase 7 Rabbit anti-Human Polyclonal (aa107-156) Antibody
Human
WB
Unconjugated
100 µl/$424
CASP7 / Caspase 7 Rabbit anti-Human Polyclonal Antibody
Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
CASP7 / Caspase 7 Rabbit anti-Human Polyclonal (N-Terminal) Antibody
Human
ELISA, ICC, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
CASP7 / Caspase 7 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, IHC-P, WB
Unconjugated
0.05 mg/$460
CASP7 / Caspase 7 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Mouse, Rat, Human
ELISA, ICC, IP, WB
Unconjugated
100 µl/$689
E. coli
His
23.8 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
CASP7 / Caspase 7 Rabbit anti-Human Polyclonal (aa149-198) Antibody
Mouse, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
CASP7 / Caspase 7 Rabbit anti-Human Polyclonal (aa180-229) Antibody
Mouse, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
CASP7 / Caspase 7 Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Rat, Pig, Human
ICC, IF, WB
Unconjugated
100 µl/$299
CASP7 / Caspase 7 Rabbit anti-Human Polyclonal (aa237-255) Antibody
Mouse, Guinea pig, Rat, Human, Monkey
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
CASP7 / Caspase 7 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
50 µg/$294; 100 µg/$360
CASP7 / Caspase 7 Rabbit anti-Human Polyclonal (150-230 aa, Internal) Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
CASP7 / Caspase 7 Rabbit anti-Human Polyclonal (Cleaved-Asp198) Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
100 µg/$357
CASP7 / Caspase 7 Rabbit anti-Human Polyclonal (Cleaved-Asp198) Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
100 µg/$357
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