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CCL3 / MIP-1-Alpha

chemokine (C-C motif) ligand 3

Monokine with inflammatory and chemokinetic properties. Binds to CCR1, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-alpha induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV).

Gene Name: chemokine (C-C motif) ligand 3
Family/Subfamily: Intercrine , Intercrine beta
Synonyms: CCL3, C-C motif chemokine 3, G0S19-1, Mip1alpha, SCYA3, SIS-beta, Chemokine (C-C motif) ligand 3, LD78ALPHA, MIP-1-alpha, MIP1A, PAT 464.1, Small-inducible cytokine A3
Target Sequences: NM_002983 NP_002974.1

Publications (2)

1
Chemokine (C-C motif) ligand 3 detection in the serum of persons exposed to asbestos: A patient-based study. Xu J, Alexander DB, Iigo M, Hamano H, Takahashi S, Yokoyama T, Kato M, Usami I, Tokuyama T, Tsutsumi M, Tamura M, Oguri T, Niimi A, Hayashi Y, Yokoyama Y, Tonegawa K, Fukamachi K, Futakuchi M, Sakai Y, Suzui M, Kamijima M, Hisanaga N, Omori T, Nakae D, Hirose A, Kanno J, Tsuda H. Cancer science. 2015 106:825-32. (IHC-P; Human) [Full Text Article] [PubMed:25940505] [PMC:PMC4520633]
2
CCL3-CCR5 axis contributes to progression of esophageal squamous cell carcinoma by promoting cell migration and invasion via Akt and ERK pathways. Takayuki Kodama, Yu-Ichiro Koma, Noriaki Arai, Aya Kido, Naoki Urakawa, Mari Nishio, Manabu Shigeoka, Hiroshi Yokozaki. Laboratory investigation; a journal of technical methods and pathology. 2020 September;100:1140-1157. [Full Text Article] [PubMed:32457351] [PMC:PMC7438203] Related Antibodies: LS-C384561.

☰ Filters
Antibodies (163)
ELISA Kits (48)
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CCL3 / MIP-1-Alpha (254)
Human (101)
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rabbit (107)
mouse (41)
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Select
CCL3 / MIP-1-Alpha Rabbit anti-Human Polyclonal (Internal) Antibody
Human
ELISA, IHC
Unconjugated
50 µl/$279; 100 µl/$309; 200 µl/$379
CCL3 / MIP-1-Alpha Antibody - Formalin-fixed and paraffin-embedded human tonsil tissue reacted with CCL3 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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CCL3 / MIP-1-Alpha Rabbit anti-Human Polyclonal (aa59-87) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
400 µl/$381
CCL3 / MIP-1-Alpha Antibody - Western Blot (reducing) of CCL3 antibody. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CCL3 / MIP-1-Alpha Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
50 µg/$325; 100 µg/$361
CCL3 / MIP-1-Alpha Antibody - Western Blot (reducing) of CCL3 antibody. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CCL3 / MIP-1-Alpha Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
25 µg/$325; 50 µg/$361
CCL3 / MIP-1-Alpha Antibody - Immunohistochemistry of paraffin-embedded human thyroid tissue using CCL3 Antibody at dilution of 1:100
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CCL3 / MIP-1-Alpha Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
50 µg/$284; 100 µg/$348
CCL3 / MIP-1-Alpha ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$475
Select
HEK 293 Cells
None
Biologically active
Less than 0.2 EU/µg protein (determined by LAL method).
7.8 kDa (SDS-PAGE)
5 µg/$250; 25 µg/$288
Select
CCL3 / MIP-1-Alpha Mouse anti-Human Monoclonal (5C75) Antibody
Human
ELISA
Unconjugated
500 µg/$548; 1 mg/$771
CCL3 / MIP-1-Alpha ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$635
Select
CHO Cells
None
Biologically active
Less than 0.2 EU/µg protein (determined by LAL method).
8-10 kDa (SDS-PAGE)
50 µg/$339; 10 µg/$258; 1 mg/$1,405
CCL3 / MIP-1-Alpha Antibody - Western Blot analysis of CCL3 expression in transfected 293T cell line by CCL3 monoclonal antibody (M01), clone 4E7.Lane 1: CCL3 transfected lysate(10.1 KDa).Lane 2: Non-transfected lysate.
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CCL3 / MIP-1-Alpha Mouse anti-Human Monoclonal (4E7) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$413
Select
CCL3 / MIP-1-Alpha Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA, Func, Neut, WB
Unconjugated
100 µg/$799
CCL3 / MIP-1-Alpha Antibody - Western Blot (non-reducing) of CCL3 antibody. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CCL3 / MIP-1-Alpha Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA, WB
Unconjugated
50 µg/$325; 100 µg/$361
CCL3 / MIP-1-Alpha Antibody - Anti-Mouse MIP-1a Antibody - Western Blot. Anti-mouse MIP-1a in western blot shows detection of recombinant mouse MIP-1a/Ccl3 raised in E. coli. Recombinant truncated (0.1 ug, 7.8 kD) protein was loaded onto and resolved by SDS-PAGE, then transferred to nitrocellulose. The membrane was blocked with 1% BSA in TBST for 30 min at RT, followed by incubation with Anti-Mouse MIP-1a/Ccl3. After washing, membrane was probed with secondary antibody Dylight 649 Conjugated Anti-Rabbit IgG (H&L) (Goat) Antibody ( diluted 1:20000 in blocking buffer (MB-070) for 30 min. at RT. Data was collected using Bio-Rad VersaDoc 4000 MP imaging system.
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CCL3 / MIP-1-Alpha Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA, WB
Unconjugated
100 µg/$498
CCL3 / MIP-1-Alpha Antibody - Immunohistochemistry of Human Lung stained with anti-MIP-1 alpha antibody
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CCL3 / MIP-1-Alpha Rabbit anti-Human Polyclonal Antibody
Human
IHC, IHC-P
Unconjugated
250 µl/$538
Select
CCL3 / MIP-1-Alpha Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA
Unconjugated
100 µl/$275; 200 µl/$312; 400 µl/$350
Select
CCL3 / MIP-1-Alpha Mouse anti-Human Monoclonal Antibody
Human
ELISA
Unconjugated
500 µg/$742
CCL3 / MIP-1-Alpha ELISA Kit
Select
Development Kit
200 Wells
Mouse
4 - 1000 pg/ml
Colorimetric - 405nm (ABTS)
1 Test/$180
CCL3 / MIP-1-Alpha ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$653
CCL3 / MIP-1-Alpha ELISA Kit
Select
Sandwich
96-Well Microplate
Human
4.13 - 3000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$537
Select
CCL3 / MIP-1-Alpha Mouse anti-Human Monoclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$805
CCL3 / MIP-1-Alpha Antibody - Sandwich ELISA of CCL3 antibody
Select
CCL3 / MIP-1-Alpha Rabbit anti-Rat Polyclonal Antibody
Rat
ELISA, WB
Unconjugated
50 µg/$325; 100 µg/$361
CCL3 / MIP-1-Alpha Antibody - Sandwich ELISA of CCL3 antibody This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
CCL3 / MIP-1-Alpha Rabbit anti-Rat Polyclonal (Biotin) Antibody
Rat
ELISA, WB
Biotin Conjugated
25 µg/$325; 50 µg/$361
Select
CCL3 / MIP-1-Alpha Rabbit anti-Rat Polyclonal (PE) Antibody
Rat
ELISA, Neut, WB
PE Conjugated
100 µl/$596
CCL3 / MIP-1-Alpha Antibody - Anti-CCL3 / MIP-1-Alpha antibody IHC staining of human lung. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50.
Select
CCL3 / MIP-1-Alpha Rabbit anti-Human Polyclonal (aa26-75) Antibody
Human
IHC, IHC-P, Peptide-ELISA
Unconjugated
50 µl/$460
Viewing 1-25 of 254 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).