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GPT / Alanine Transaminase

glutamic-pyruvate transaminase (alanine aminotransferase)

GPT / Alanine Transaminase is cytosolic alanine aminotransaminase 1 (ALT1); also known as glutamate-pyruvate transaminase 1. This enzyme catalyzes the reversible transamination between alanine and 2-oxoglutarate to generate pyruvate and glutamate and, therefore, plays a key role in the intermediary metabolism of glucose and amino acids. Serum activity levels of this enzyme are routinely used as a biomarker of liver injury caused by drug toxicity, infection, alcohol, and steatosis. A related gene on chromosome 16 encodes a putative mitochondrial alanine aminotransaminase.

Gene Name:	glutamic-pyruvate transaminase (alanine aminotransferase)
Synonyms:	GPT, AAT1, ALT1, Alanine aminotransferase, Alanine aminotransferase 1, GPT 1, GPT1
Target Sequences:	NM_005309 NP_005300.1 P24298

Alanine Transaminase (ALT) Assay Kit (Colorimetric) - LS-K308

Type:

Detection/Quantition

Target:

GPT / Alanine Transaminase

Application:

Spectrophotometry (visible)

Price:

100 Tests/$450

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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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