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Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
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IDH1 / IDH

isocitrate dehydrogenase 1 (NADP+), soluble

Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the cytoplasm and peroxisomes. It contains the PTS-1 peroxisomal targeting signal sequence. The presence of this enzyme in peroxisomes suggests roles in the regeneration of NADPH for intraperoxisomal reductions, such as the conversion of 2, 4-dienoyl-CoAs to 3-enoyl-CoAs, as well as in peroxisomal reactions that consume 2-oxoglutarate, namely the alpha-hydroxylation of phytanic acid. The cytoplasmic enzyme serves a significant role in cytoplasmic NADPH production. Alternatively spliced transcript variants encoding the same protein have been found for this gene.

Gene Name: isocitrate dehydrogenase 1 (NADP+), soluble
Synonyms: IDH1, IDCD, IDP, IDPC, PICD, NADP(+)-specific ICDH, IDH, Oxalosuccinate decarboxylase
Target Sequences: NM_005896 NP_005887.2 O75874

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Antibodies (117)
Proteins (33)
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IDH1 / IDH (164)
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IDH1 / IDH Antibody - Anti-IDH1 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Cancer Pathology
Cancer
IDH1 / IDH Rabbit anti-Human Polyclonal (aa290-339) Antibody
Rat, Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
IDH1 / IDH Antibody - Anti-IDH1 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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Cancer Pathology
Cancer
IDH1 / IDH Rabbit anti-Human Polyclonal Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
IDH1 / IDH Antibody - Formalin-fixed and paraffin-embedded human brain reacted with IDH1 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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IDH1 / IDH Rabbit anti-Human Polyclonal (aa63-90) Antibody
Mouse, Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
400 µl/$393
IDH1 / IDH Antibody - Anti-IDH1 antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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IDH1 / IDH Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, IHC-P, WB
Unconjugated
0.05 mg/$460
IDH1 / IDH Antibody - Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Cancer Pathology
Cancer
IDH1 / IDH Mouse anti-Human Monoclonal (AT25H10) Antibody
Human
ELISA, ICC, IF, IHC-P, WB
Unconjugated
100 µl/$460
IDH1 / IDH Antibody - Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Cancer Pathology
Cancer
IDH1 / IDH Mouse anti-Human Monoclonal (C13) Antibody
Mouse, Pig, Human
ICC, IHC-P, WB
Unconjugated
50 µl/$460
IDH1 / IDH Antibody - Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Cancer Pathology
Cancer
IDH1 / IDH Rabbit anti-Human Polyclonal (aa116-143) Antibody
Mouse, Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$460
IDH1 / IDH Antibody - IHC of paraffin-embedded Human pancreas tissue using anti-IDH1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min).
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IDH1 / IDH Mouse anti-Human Monoclonal (OTI1D1) Antibody
Mouse, Dog, Rat, Human, Monkey
IHC, IHC-P, WB
Unconjugated
100 µl/$434
IDH1 / IDH Antibody - Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Cancer Pathology
Cancer
IDH1 / IDH Mouse anti-Human Monoclonal (C12) Antibody
Mouse, Rat, Pig, Human
ICC, IHC-P, WB
Unconjugated
50 µl/$460
IDH1 / IDH Antibody - Formalin-fixed, paraffin-embedded human colon carcinoma stained with IDH1 antibody (IDH1/1152).  This image was taken for the unmodified form of this product. Other forms have not been tested.
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IDH1 / IDH Mouse anti-Human Monoclonal (aa280-420) (IDH1/1152) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
20 µg/$371; 100 µg/$574
IDH1 / IDH Antibody - Formalin-fixed, paraffin-embedded human colon carcinoma stained with IDH1 antibody (IDH1/1152).  This image was taken for the unmodified form of this product. Other forms have not been tested.
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IDH1 / IDH Mouse anti-Human Monoclonal (aa280-420) (Ready-to-Use) (IDH1/1152) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated, Ready-to-Use
7 ml/$574
IDH1 / IDH Antibody - Formalin-fixed, paraffin-embedded human colon carcinoma stained with IDH1 antibody (IDH1/1152).  This image was taken for the unmodified form of this product. Other forms have not been tested.
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IDH1 / IDH Mouse anti-Human Monoclonal (aa280-420) (Azide-free, BSA-free) (IDH1/1152) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated, Azide-free, BSA-free
100 µg/$574
IDH1 / IDH ELISA Kit
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Sandwich CLIA
96-Well Strip Plate
Human
0.69 - 500 ng/ml
Chemiluminescent
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$851
IDH1 / IDH Antibody - IHC of paraffin-embedded Human endometrium tissue using anti-IDH1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min).
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IDH1 / IDH Mouse anti-Human Monoclonal (OTI3G9) Antibody
Mouse, Dog, Rat, Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
IDH1 / IDH Antibody - Immunofluorescence analysis of Hela cells using IDH1 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher
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IDH1 / IDH Mouse anti-Human Monoclonal (7G8A1) Antibody
Human
ELISA, Flo, IHC, WB
Unconjugated
100 µl/$459
IDH1 / IDH Antibody - Immunohistochemical staining of paraffin-embedded breast tissue using anti-IDH1 mouse monoclonal antibody. (Dilution 1:50).
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IDH1 / IDH Mouse anti-Human Monoclonal (OTI2H9) Antibody
IF, IHC, IHC-P, WB
Unconjugated
100 µl/$450
IDH1 / IDH Antibody - Western blot of Inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase antibody at 2 ug/ml with recombinant Inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase protein 0.1 ug Secondary.
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IDH1 / IDH Rabbit anti-Bacillus subtilis Polyclonal Antibody
Bacillus subtilis
ELISA, WB
Unconjugated
50 µg/$294
IDH1 / IDH Antibody - IDH1 antibody (0.5 ug/ml) staining of S. cerevisiae S288c lysate (35 ug protein/ml in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. The blocking buffer contained non-animal derived protein.
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IDH1 / IDH Goat anti-Human Polyclonal (aa281-295) Antibody
Human, Yeast
Peptide-ELISA, WB
Unconjugated
100 µg/$503
IDH1 / IDH Antibody - IDH1 antibody (0.1 ug/ml) staining of HepG2 lysate (35 ug protein/ml in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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IDH1 / IDH Goat anti-Human Polyclonal (aa65-77) Antibody
Human
Peptide-ELISA, WB
Unconjugated
100 µg/$503
IDH1 / IDH Antibody - Immunohistochemistry of paraffin-embedded human adrenal gland tissue at dilution of 1:100
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IDH1 / IDH Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$294; 100 µg/$360
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IDH1 / IDH Rabbit anti-Human Polyclonal Antibody
Human
ELISA, Flo, IF, IHC, IP, WB
Unconjugated
100 µg/$331
IDH1 / IDH Antibody - Immunohistochemistry of paraffin-embedded mouse heart.
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IDH1 / IDH Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ChIP-Seq, IF, IHC, IP, WB
Unconjugated
20 µl/$275; 100 µl/$389
IDH1 / IDH Antibody - Immunohistochemistry of paraffin-embedded human testicle using antibody at 1:100 dilution.
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IDH1 / IDH Rabbit anti-Human Polyclonal (aa1-240) Antibody
Mouse, Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$294; 100 µl/$360
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IDH1 / IDH Rabbit anti-Pig Polyclonal Antibody
Pig
ELISA, IF, IHC, WB
Unconjugated
10 mg/$335
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IDH1 / IDH Rabbit anti-Pig Polyclonal Antibody
Pig
ELISA, IF, IHC, WB
Unconjugated
1 mg/$520
Viewing 1-25 of 164 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).