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KRT5 / CK5 / Cytokeratin 5

keratin 5

The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. Mutations in these genes have been associated with a complex of diseases termed epidermolysis bullosa simplex. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.

Gene Name: keratin 5
Family/Subfamily: Keratin , not assigned-Keratin
Synonyms: KRT5, 58 kd cytokeratin, 58 kDa cytokeratin, CK5, CK-5, Cytokeratin-5, DDD, EBS2, Keratin 5, KRT5A, Type-II keratin Kb5, Cytokeratin 5, K5, Keratin-5
Target Sequences: NM_000424 NP_000415.2 P13647

Publications (6)

1
A case of primary combined neuroendocrine carcinoma with squamous cell carcinoma in the upper gingiva. Mochizuki Y, Omura K, Sakamoto K, Nakanishi S, Satoh K, Marukawa E, Yamaguchi A. Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics. 2010 109:e34-9. (IHC) [PubMed:20303044]
2
Aldosterone and angiotensin II induce protein aggregation in renal proximal tubules. Cheema MU, Poulsen ET, Enghild JJ, Hoorn EJ, Fenton RA, Praetorius J. Physiological reports. 2013 1:e00064. (WB; Human) [Full Text Article] [PubMed:24303148] [PMC:PMC3831891] Related Antibodies: LS-B5496.
3
Intravesical Administration of Xenogeneic Porcine Urothelial Cells Attenuates Cyclophosphamide-Induced Cystitis in Mice. Huang CP, Chen CC, Tsai YT, Wu CC, Shyr CR. Cell transplantation. 2019 March;28:296-305. [Full Text Article] [PubMed:30675801] [PMC:PMC6425110]
4
Insights into Early Recovery from Influenza Pneumonia by Spatial and Temporal Quantification of Putative Lung Regenerating Cells and by Lung Proteomics. Ong JWJ, Tan KS, Ler SG, Gunaratne J, Choi H, Seet JE, Chow VT. Cells. 2019 August;8:E975. [Full Text Article] [PubMed:31455003] [PMC:PMC6769472] Related Antibodies: LS-C22715.
5
Human oral mucosa cell atlas reveals a stromal-neutrophil axis regulating tissue immunity. Drake Winslow Williams, Teresa Greenwell-Wild, Laurie Brenchley, Nicolas Dutzan, Andrew Overmiller, Andrew Phillip Sawaya, Simone Webb, Daniel Martin, NIDCD/NIDCR Genomics and Computational Biology Core ; George Hajishengallis, Kimon Divaris, Maria Morasso, Muzlifah Haniffa, Niki Maria Moutsopoulos. Cell. 2021 July;184:4090-4104.e15. [Full Text Article] [PubMed:34129837] [PMC:PMC8359928] Related Antibodies: LS-C22715.
6
FOXM1 network in association with TREM1 suppression regulates NET formation in diabetic foot ulcers. Andrew P Sawaya, Rivka C Stone, Spencer Mehdizadeh, Irena Pastar, Stephen Worrell, Nathan C Balukoff, Mariana J Kaplan, Marjana Tomic-Canic, Maria I Morasso. EMBO reports. 2022 August;23:e54558. [Full Text Article] [PubMed:35856334] [PMC:PMC9346470] Related Antibodies: LS-C22715.
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KRT5 / CK5 / Cytokeratin 5 (6)
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KRT5 / CK5 / Cytokeratin 5 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$764
KRT5 / CK5 / Cytokeratin 5 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
78 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
KRT5 / CK5 / Cytokeratin 5 ELISA Kit
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Cell-Based
96-Well Microplate
Mouse, Human, Rat
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
1 Plate/$534
KRT5 / CK5 / Cytokeratin 5 ELISA Kit
Select
Custom
96-Well Strip Plate
Rat
Colorimetric - 450nm (TMB)
1 Plate/$669
KRT5 / CK5 / Cytokeratin 5 ELISA Kit
Select
Custom
96-Well Strip Plate
Colorimetric - 450nm (TMB)
1 Plate/$669
KRT5 / CK5 / Cytokeratin 5 ELISA Kit
Select
Custom
96-Well Strip Plate
Mouse
Colorimetric - 450nm (TMB)
1 Plate/$669
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).