Products
Research Areas
COVID-19
Resources
Login
Quick Order
Cart Cart lightblue
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Contact Us

Locations


Orders Processing,
Shipping & Receiving,
Warehouse

2 Shaker Rd Suites
B001/B101
Shirley, MA 01464


Production Lab

Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036

Telephone Numbers



Tel: +1 (206) 374-1102
Fax: +1 (206) 577-4565

Contact Us



Additional Contact Details

Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Catalog Number Size Price
LS-B5496-50 50 µl (1 mg/ml) $460 
KRT5 / CK5 / Cytokeratin 5 Antibody - Anti-KRT5 / Cytokeratin 5 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.
KRT5 / CK5 / Cytokeratin 5 Antibody - Western blot analysis of lysates from HepG2 cells, using Keratin 5 Antibody. The lane on the right is blocked with the synthesized peptide.
KRT5 / CK5 / Cytokeratin 5 Antibody - Anti-KRT5 / Cytokeratin 5 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.
KRT5 / CK5 / Cytokeratin 5 Antibody - Western blot analysis of lysates from HepG2 cells, using Keratin 5 Antibody. The lane on the right is blocked with the synthesized peptide.
1 of 2
2 of 2

PathPlus™ Polyclonal Rabbit anti‑Human KRT5 / CK5 / Cytokeratin 5 Antibody (aa541‑590, IHC, WB) LS‑B5496

PathPlus™ Polyclonal Rabbit anti‑Human KRT5 / CK5 / Cytokeratin 5 Antibody (aa541‑590, IHC, WB) LS‑B5496

Note: This antibody replaces LS-C118501
Antibody:
KRT5 / CK5 / Cytokeratin 5 Rabbit anti-Human Polyclonal (aa541-590) Antibody
Application:
IHC, IHC-P, WB, Peptide-ELISA
Reactivity:
Human, Mouse, Rat
Format:
Unconjugated, Unmodified
Price
Catalog Number
$460
LS-B5496-50
Toll Free North America
206-374-1102
For Research Use Only

Overview

Antibody:
KRT5 / CK5 / Cytokeratin 5 Rabbit anti-Human Polyclonal (aa541-590) Antibody
Application:
IHC, IHC-P, WB, Peptide-ELISA
Reactivity:
Human, Mouse, Rat
Format:
Unconjugated, Unmodified

Specifications

Description
KRT5 (Cytokeratin 5, CK5) is a protein that dimerizes with keratin 14 to form the intermediate filament that form the cytoskeleton of basal epithelial cells. It is useful for identifying myoepithelial cells and basal cells in the breast, skin, salivary glands, and prostate. It is present in the skin, the mucosa of the oral cavity, oropharynx, hypopharynx, and larynx, and in mitotically active basal cells of the skin. It is commonly positive in squamous carcinomas of the head and neck, as well as in mesotheliomas. Mutations in KRT5 cause epidermolysis bullosa simplex. Commonly used with Cytokeratin 6, the CK5/6 marker is useful for the identification of mesotheliomas as well as identifying the presence of basal epithelium in benign glands versus malignant prostate and breast carcinomas, where the basal layer is lost. References: Int J Clin Exp pathol 2008 1(1):19; Histopathology 1997 31:140; J Cell Sci 1994 107(4):765
Target
Human KRT5 / CK5 / Cytokeratin 5
Synonyms
KRT5 | 58 kd cytokeratin | 58 kDa cytokeratin | CK5 | CK-5 | Cytokeratin-5 | DDD | EBS2 | Keratin 5 | KRT5A | Type-II keratin Kb5 | Cytokeratin 5 | K5 | Keratin-5
Host
Rabbit
Reactivity
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic peptide from human Keratin 5. (AA Range: 541-590)
Epitope
aa541-590
Specificity
Keratin 5 Antibody detects endogenous levels of total Keratin 5 protein.
Applications
  • IHC
  • IHC - Paraffin (1:200)
  • Western blot (1:500 - 1:1000)
  • Peptide Enzyme-Linked Immunosorbent Assay (1:10000)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Usage
Western Blot: Predicted MW 62 kDa
Presentation
PBS (without Mg2+, Ca2+), pH 7.4, 150 mM NaCl, 0.02% Sodium Azide, 50% Glycerol
Storage
Short term: store at 4°C. Long term: aliquot and store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About KRT5 / CK5 / Cytokeratin 5
P13647 NM_000424 NP_000415.2

Validation

KRT5 / CK5 / Cytokeratin 5 Antibody - Anti-KRT5 / Cytokeratin 5 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.
Anti-KRT5 / Cytokeratin 5 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.
Anti-KRT5 / Cytokeratin 5 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.

LSBio Ratings

PathPlus™ KRT5 / CK5 / Cytokeratin 5 Antibody (aa541-590) for IHC, WB/Western LS-B5496 has an LSBio Rating of
Publications (4)
Laboratory Validation Score (5)

Publications (1)

Aldosterone and angiotensin II induce protein aggregation in renal proximal tubules. Cheema MU, Poulsen ET, Enghild JJ, Hoorn EJ, Fenton RA, Praetorius J. Physiological reports. 2013 1:e00064. (WB; Human)

Customer Reviews (0)


Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 10/9/2024