Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Forgot password?
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Quick Order
Products
Antibodies
ELISA and Assay Kits
Research Areas
Infectious Disease
Resources
Purchasing
Reference Material
Contact Us
Location
Corporate Headquarters
Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States
Telephone Numbers
Customer Service: (800) 227-6666 / (650) 697-3600
Contact Us
Additional Contact Details
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Forgot password?
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Quick Order
NF-L / NEFL
neurofilament, light polypeptide
Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y.
| Gene Name: | neurofilament, light polypeptide |
| Synonyms: | NEFL, 68 kDa neurofilament protein, CMT1F, CMT2E, NF68, NF-L, NFL, Neurofilament subunit NF-L, PPP1R110, Neurofilament light polypeptide, CMTDIG |
| Target Sequences: | NM_006158 NP_006149.2 P07196 |
Publications (5)
1
Neuron-glia interactions underlie ALS-like axonal cytoskeletal pathology. King AE, Dickson TC, Blizzard CA, Woodhouse A, Foster SS, Chung RS, Vickers JC. Neurobiology of aging. 2011 32:459-69. (ICC, IHC; Mouse)
[PubMed:19427060]
2
NYAP: a phosphoprotein family that links PI3K to WAVE1 signalling in neurons. Yokoyama K, Tezuka T, Kotani M, Nakazawa T, Hoshina N, Shimoda Y, Kakuta S, Sudo K, Watanabe K, Iwakura Y, Yamamoto T. The EMBO journal. 2011 30:4739-54.
[PubMed:21946561]
[PMC:PMC3243607]
3
Microbiome-Derived Lipopolysaccharide (LPS) Selectively Inhibits Neurofilament Light Chain (NF-L) Gene Expression in Human Neuronal-Glial (HNG) Cells in Primary Culture. Lukiw WJ, Cong L, Jaber V, Zhao Y. Frontiers in neuroscience. 2018 December;12:896. [Full Text Article]
[PubMed:30568571]
[PMC:PMC6289986]
☰ Filters
Products
Antibodies
(64)
ELISA Kits
(21)
Proteins
(9)
Type
Competitive EIA
(4)
Over-Expression Lysate
(2)
Primary
(64)
Recombinant
(7)
Sandwich
(16)
Sandwich CLIA
(1)
Target
NF-L / NEFL
(94)
Reactivity
Human
(61)
Mouse
(34)
Rat
(30)
Avian
(2)
Bovine
(7)
Chicken
(3)
Mammal
(1)
Monkey
(3)
Opossum
(1)
Pig
(13)
Porcine
(1)
Rabbit
(2)
Sheep
(1)
Application
IHC
(27)
IHC-Fr
(5)
IHC-P
(17)
WB
(54)
Flo
(3)
ELISA
(15)
ICC
(8)
IF
(13)
IHC-Fx
(1)
IP
(8)
Peptide-ELISA
(2)
Host
rabbit
(32)
mouse
(27)
goat
(1)
chicken
(4)
Product Group
IHCPlus
(3)
PathPlus Cancer
(3)
Isotype
IgG
(13)
IgG1
(13)
IgG1,k
(8)
IgG2a
(1)
IgG2b
(3)
IgY
(2)
Clonality
monoclonal mc
(27)
polyclonal pc
(35)
recombinant monoclonal rmc
(2)
Clone
1H3
(2)
2F11
(1)
2G10
(1)
7D1
(1)
ABT-NF
(1)
DA2
(3)
NEFL/2983R
(2)
NF-68
(3)
OTI11F6
(2)
OTI2F5
(2)
OTI3G2
(2)
Format
12 x 8-Well Microstrips
(1)
96-Well Microplate
(2)
96-Well Strip Plate
(18)
APC
(2)
APC Conjugated
(3)
Azide-free
(1)
Biotin Conjugated
(4)
Carrier-free
(4)
Cy3 Conjugated
(2)
Cy7 Conjugated
(2)
FITC Conjugated
(4)
HRP Conjugated
(4)
Magnetic beads Conjugated
(1)
PE Conjugated
(3)
Sepharose Conjugated
(1)
Unconjugated
(40)
Epitope
aa139-234
(8)
aa281-396
(8)
aa1-360
(3)
aa128-271
(2)
C-Terminus
(1)
C-terminal
(1)
Internal
(1)
aa295-344
(1)
aa330-343
(1)
aa485-530
(1)
Publications
No
(93)
Yes
(1)
Sample Type
Cell Culture Supernatants
(9)
Cell Lysates
(5)
Plasma
(18)
Serum
(18)
Tissue Homogenates
(11)
Tag
10His, N-terminus
(1)
10His-SUMO, N-terminus + Myc, C-terminus
(1)
6His, N-terminus
(1)
GST
(1)
His
(2)
Myc-DDK (Flag)
(3)
Species
Human
(6)
Mouse
(2)
Source
293T Cells
(1)
E. coli
(4)
HEK 293 Cells
(2)
Wheat Germ Extract
(1)
Yeast
(1)
Purification
Purified
(3)
Low Endotoxin Level
Low endotoxin level
(1)
NF-L / NEFL Mouse anti-Human Monoclonal (OTI3G2) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
Sandwich
96-Well Strip Plate
Human
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$730
Sandwich
96-Well Strip Plate
Human
31.2 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates
1 Plate/$669
Sandwich
96-Well Strip Plate
Rat
78 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
Sandwich
96-Well Strip Plate
Pig
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates
1 Plate/$669
Competitive EIA
96-Well Strip Plate
Mouse
4.94 - 400 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$811
Sandwich CLIA
12 x 8-Well Microstrips
Human
12.5 - 800 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$728
Sandwich
96-Well Strip Plate
Monkey
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$728
Sandwich
96-Well Strip Plate
Rat
15.63 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
Sandwich
96-Well Strip Plate
Mouse
78 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates
1 Plate/$669
E. coli
542 AA
His
Less than 0.1 EU/µg protein (determined by LAL method).
59.73 kDa
10 mg/$4,268; 5 mg/$3,201; 1 mg/$1,868; 0.5 mg/$1,475; 200 µg/$1,103; 100 µg/$756; 50 µg/$531
Yeast
6His, N-terminus
63.38 kD
100 µg/$499; 20 µg/$364; 1 mg/$1,683
Sandwich
96-Well Microplate
Human
15.63 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
Sandwich
96-Well Strip Plate
Mouse
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$854
Competitive EIA
96-Well Strip Plate
Human
123.5 - 10000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$798
Sandwich
96-Well Strip Plate
Porcine
15.63 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$728
NF-L / NEFL Mouse anti-Human Monoclonal (DA2) Antibody
Human
ELISA, IHC, IHC-Fr, IHC-P, IP, WB
Unconjugated
200 µg/$890
NF-L / NEFL Chicken anti-Human Polyclonal Antibody
Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
50 µl/$460
NF-L / NEFL Rabbit anti-Human Polyclonal (aa128-271) (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
E. coli
His
12.6 kDa
10 µg/$267; 50 µg/$352; 100 µg/$562; 200 µg/$702; 1 mg/$1,723; 500 µg/$1,298; 5 mg/$2,673; 2 mg/$1,900
Competitive EIA
96-Well Strip Plate
Rat
123.5 - 10000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$750
NF-L / NEFL Mouse anti-Pig Monoclonal (DA2) Antibody
Mouse, Bovine, Rat, Pig, Human
ICC, IF, WB
Unconjugated
100 µl/$376
Cancer
NF-L / NEFL Mouse anti-Human Monoclonal (2F11) Antibody
Opossum, Human
IHC, IHC-Fr, IHC-P, WB
Unconjugated
0.1 mg/$485
NF-L / NEFL Mouse anti-Human Monoclonal (2G10) Antibody
Human
ELISA, Flo, IF, IHC, WB
Unconjugated
100 µl/$459
NF-L / NEFL Mouse anti-Pig Monoclonal (DA2) Antibody
Avian, Pig, Mammal, Mouse, Rat, Human
IF, IHC, IHC-Fx, IHC-P, WB
Unconjugated
0.05 ml/$386
Viewing 1-25
of 94
product results
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.
