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PDCD1 / CD279 / PD-1
programmed cell death 1
PDCD1 / CD279 / PD-1 is a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases.
| Gene Name: | programmed cell death 1 |
| Family/Subfamily: | Apoptosis |
| Synonyms: | PDCD1, CD279, HPD-1, HPD-l, PD1, Protein PD-1, SLEB2, PD-1, CD279 antigen, Programmed cell death 1 |
| Target Sequences: | NM_005018 NP_005009.2 Q15116 |
Publications (9)
1
Simian immunodeficiency virus (SIV)-specific CD8+ T-cell responses in vervet African green monkeys chronically infected with SIVagm. Zahn RC, Rett MD, Korioth-Schmitz B, Sun Y, Buzby AP, Goldstein S, Brown CR, Byrum RA, Freeman GJ, Letvin NL, Hirsch VM, Schmitz JE. Journal of virology. 2008 82:11577-88.
[PubMed:18829748]
[PMC:PMC2583661]
Related Antibodies: LS-C40800.
2
Cutting edge: Programmed death-1/programmed death ligand 1 interaction regulates the induction and maintenance of invariant NKT cell anergy. Chang WS, Kim JY, Kim YJ, Kim YS, Lee JM, Azuma M, Yagita H, Kang CY. Journal of immunology (Baltimore, Md. : 1950). 2008 181:6707-10.
[PubMed:18981087]
Related Antibodies: LS-C40800.
3
Human immunodeficiency virus type 1 escapes from interleukin-2-producing CD4+ T-cell responses without high-frequency fixation of mutations. Jones RB, Yue FY, Gu XX, Hunter DV, Mujib S, Gyenes G, Mason RD, Mohamed R, MacDonald KS, Kovacs C, Ostrowski MA. Journal of virology. 2009 83:8722-32.
[PubMed:19553327]
[PMC:PMC2738181]
Related Antibodies: LS-C40800.
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Cancer Pathology
Cancer
PDCD1 / CD279 / PD-1 Mouse anti-Human Monoclonal (3C6) Antibody
Human
Flo, IHC, IHC-P
Unconjugated
50 µl/$460
PDCD1 / CD279 / PD-1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
0.05 mg/$460
Cancer Pathology
Cancer
PDCD1 / CD279 / PD-1 Mouse anti-Human Monoclonal (11B2) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
50 µl/$440
PDCD1 / CD279 / PD-1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, ICC, IF, IHC, IHC-P, WB
Unconjugated
0.05 mg/$545
PDCD1 / CD279 / PD-1 Mouse anti-Human Monoclonal (J116) Antibody
Human
Flo, IHC, IHC-Fr, IHC-P, IP, WB
Unconjugated
50 µg/$460
PDCD1 / CD279 / PD-1 Mouse anti-Human Monoclonal (EH12.2H7) Antibody
Human
Flo
Unconjugated
100 µg/$268
PDCD1 / CD279 / PD-1 Mouse anti-Mouse Monoclonal (7A11B1) Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
0.1 mg/$502
PDCD1 / CD279 / PD-1 Rabbit anti-Human Polyclonal (aa41-132) Antibody
Human
ICC, IP, WB
Unconjugated
100 µl/$299; 200 µl/$337; 500 µl/$463; 1 ml/$527; 2 ml/$682; 5 ml/$1,141
PDCD1 / CD279 / PD-1 Mouse anti-Human Monoclonal (aa21-167) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$586
PDCD1 / CD279 / PD-1 Mouse anti-Human Monoclonal (aa21-167) (4F12) Antibody
Human
ELISA, WB
Unconjugated
50 µl/$303; 100 µl/$365
PDCD1 / CD279 / PD-1 Rabbit anti-Human Monoclonal (RMPD1-1) Antibody
Human
IHC, IHC-P
Unconjugated
20 µg/$371; 100 µg/$574
PDCD1 / CD279 / PD-1 Mouse anti-Human Monoclonal (NAT-105) Antibody
Human
IHC, IHC-Fr, IHC-P
Unconjugated
0.1 ml/$332
Sandwich
96-Well Microplate
Human
24.58 - 6000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$635
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
Cancer Pathology
Cancer
PDCD1 / CD279 / PD-1 Mouse anti-Human Monoclonal (5D3) Antibody
Human
ELISA, Flo, ICC, IF, IHC-P
Unconjugated
0.1 mg/$485
PDCD1 / CD279 / PD-1 Mouse anti-Human Monoclonal (8H7) Antibody
Human
Flo, ICC, IF, IHC, IHC-P, WB
Unconjugated
50 µl/$460
![PDCD1 / CD279 / PD-1 Antibody - (A) Immunohistochemistry of PD-1 in human breast cancer tissue with PD-1 [4C7] antibody at 10 ug/mL. (B) Immunohistochemistry in human breast cancer tissue with control mouse IgG staining at 10 ug/mL.](https://lsbio-7d62.kxcdn.com/image2/pdcd1-cd279-pd-1-antibody-clone-4c7-ls-c669064/484731_4958030.gif)
PDCD1 / CD279 / PD-1 Mouse anti-Human Monoclonal (4C7) Antibody
Human
ELISA, Flo, ICC, IF, IHC-P, WB
Unconjugated
0.1 mg/$502
PDCD1 / CD279 / PD-1 Mouse anti-Human Monoclonal (OTI4F10) Antibody
Human
IHC, IHC-P
Unconjugated
100 µl/$434
PDCD1 / CD279 / PD-1 Mouse anti-Human Monoclonal (PE) (EH12.2H7) Antibody
Human, Non-Human Primates
Flo, Func, IHC-Fr
PE Conjugated
100 Tests/$365
PDCD1 / CD279 / PD-1 Goat anti-Mouse Polyclonal (Extracellular Domain) Antibody
Mouse
ELISA, Flo, IHC, WB
Unconjugated
100 µg/$962
PDCD1 / CD279 / PD-1 Rabbit anti-Rat Polyclonal (aa39-266) Antibody
Rat
WB
Unconjugated
100 µl/$306; 200 µl/$347; 500 µl/$484; 1 ml/$553; 2 ml/$737; 5 ml/$1,206
PDCD1 / CD279 / PD-1 Rabbit anti-Rat Polyclonal (aa39-266) (APC) Antibody
Rat
WB
APC Conjugated
100 µl/$402; 200 µl/$484; 500 µl/$834; 1 ml/$991; 2 ml/$1,277; 5 ml/$2,395
PDCD1 / CD279 / PD-1 Mouse anti-Human Monoclonal (2F6) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
50 µl/$460
PDCD1 / CD279 / PD-1 Mouse anti-Human Monoclonal (4E5) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
50 µl/$460
Viewing 1-25
of 313
product results
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