PDCD4

programmed cell death 4 (neoplastic transformation inhibitor)

This gene encodes a protein localized to the nucleus in proliferating cells. Expression of this gene is modulated by cytokines in natural killer and T cells. The gene product is thought to play a role in apoptosis but the specific role has not yet been determined. Two transcripts encoding different isoforms have been identified. PDCD4 inhibits the translation initiation factor E1F4A. Phosphorylation by AKT causes nuclear translocation of PDCD4 and also decreases the ability of PDCD4 to interfere with the transactivation of AP-1 responsive promoter by c-JUN. Loss of PDCD4 expression in human lung carcinoma correlates with tumor progression and prognosis.

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Products

ELISA Kits (9)

Type

Cell-Based (1)

Cell-Based Phosphorylation (2)

Custom (2)

Sandwich (4)

Target

PDCD4 (9)

Reactivity

Human (6)

Mouse (4)

Rat (4)

Chicken (1)

Format

96-Well Microplate (3)

96-Well Strip Plate (6)

Publications

No (9)

Sample Type

Adherent Cell Cultures (3)

Cell Lysates (1)

Plasma (3)

Serum (3)

Tissue Homogenates (2)

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Mouse PDCD4 (Sandwich ELISA) ELISA Kit - LS-F19748

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

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Mouse/Human/Rat PDCD4 (Cell-Based ELISA) ELISA Kit - LS-F2229

Type:

Cell-Based

Format:

96-Well Microplate

Reactivity:

Mouse, Human, Rat

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

1 Plate/$534

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Human PDCD4 (Sandwich ELISA) ELISA Kit - LS-F12280

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

Select

Human PDCD4 (Sandwich ELISA) ELISA Kit - LS-F33697

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

Select

Human PDCD4 (Sandwich ELISA) ELISA Kit - LS-F25579

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

1 Plate/$792

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Chicken PDCD4 (Custom ELISA) ELISA Kit - LS-F19746

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Chicken

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$783

Select

Rat PDCD4 (Custom ELISA) ELISA Kit - LS-F19747

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Rat

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

Select

Mouse/Human/Rat Phospho-PDCD4 (Ser67) (Cell-Based Phosphorylation ELISA) ELISA Kit - LS-F1425

Type:

Cell-Based Phosphorylation

Format:

96-Well Microplate

Reactivity:

Mouse, Human, Rat

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

1 Plate/$668

Select

Mouse/Human/Rat Phospho-PDCD4 (Ser457) (Cell-Based Phosphorylation ELISA) ELISA Kit - LS-F1426

Type:

Cell-Based Phosphorylation

Format:

96-Well Microplate

Reactivity:

Mouse, Human, Rat

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

1 Plate/$668

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