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PXN / Paxillin
paxillin
PXN / Paxillin is a cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Alternatively spliced transcript variants encoding different isoforms have been described for this gene. These isoforms exhibit different expression pattern, and have different biochemical, as well as physiological properties (PMID:9054445).
| Gene Name: | paxillin |
| Synonyms: | PXN, Paxillin |
| Target Sequences: | NM_002859 NP_002850.2 P49023 |
Publications (3)
1
RhoC GTPase is required for PC-3 prostate cancer cell invasion but not motility. Yao H, Dashner EJ, van Golen CM, van Golen KL. Oncogene. 2006 25:2285-96.
[PubMed:16314838]
2
GIT1 utilizes a focal adhesion targeting-homology domain to bind paxillin. Schmalzigaug R, Garron ML, Roseman JT, Xing Y, Davidson CE, Arold ST, Premont RT. Cellular signalling. 2007 19:1733-44. (ICC, IP)
[PubMed:17467235]
[PMC:PMC2025689]
3
Podosomes are present in a postsynaptic apparatus and participate in its maturation. Proszynski TJ, Gingras J, Valdez G, Krzewski K, Sanes JR. Proceedings of the National Academy of Sciences of the United States of America. 2009 106:18373-8.
[PubMed:19822767]
[PMC:PMC2775295]
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Products
Antibodies
(128)
Type
Primary
(128)
Target
PXN / Paxillin
(128)
Reactivity
Human
(124)
Mouse
(63)
Rat
(53)
Bat
(1)
Bovine
(11)
Chicken
(17)
Chimpanzee
(3)
Dog
(2)
Gibbon
(3)
Guinea pig
(1)
Horse
(3)
Monkey
(8)
Pig
(3)
Rabbit
(3)
Sheep
(1)
Zebrafish
(1)
Application
IHC
(27)
IHC-Fr
(1)
IHC-P
(8)
WB
(123)
ELISA
(31)
ICC
(13)
IF
(7)
IP
(13)
Peptide-ELISA
(11)
Host
rabbit
(99)
mouse
(28)
sheep
(1)
Isotype
IgG
(49)
IgG1
(22)
IgG1,k
(2)
IgG2a
(3)
IgG2b
(1)
Clonality
monoclonal mc
(26)
polyclonal pc
(100)
recombinant monoclonal rmc
(2)
Clone
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(1)
LD2 sAB
(1)
LD4 sAB
(1)
OTI1H10
(2)
OTI2B8
(2)
OTI6B7
(2)
OTI6G9
(2)
OTI8C12
(2)
PAX-14
(3)
Format
APC
(3)
APC Conjugated
(5)
Azide-free
(1)
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(7)
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(5)
Cy3 Conjugated
(3)
Cy7 Conjugated
(3)
FITC Conjugated
(7)
HRP Conjugated
(7)
Magnetic beads Conjugated
(1)
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(5)
Preservative Free
(1)
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(1)
Unconjugated
(89)
Epitope
pTyr118
(10)
pTyr31
(9)
aa201-461
(8)
aa327-568
(8)
aa347-578
(8)
Tyr118
(7)
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(4)
aa111-160
(4)
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(4)
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(3)
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(3)
120-200 aa
(2)
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(2)
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(2)
aa1-50
(2)
aa59-274
(2)
10-90 aa
(1)
210-290 aa
(1)
50-130 aa
(1)
Gln82
(1)
Leu25
(1)
Ser178
(1)
aa123-172
(1)
aa144-193
(1)
aa15-64
(1)
aa217-266
(1)
aa238-287
(1)
aa33-82
(1)
aa456-472
(1)
p118
(1)
p178
(1)
p272
(1)
p31
(1)
pSer126
(1)
pSer17
(1)
pSer272
(1)
Publications
No
(128)
PXN / Paxillin Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Rat, Human
IHC, IHC-P, IP, WB
Unconjugated
100 µl/$299
PXN / Paxillin Rabbit anti-Human Polyclonal (Tyr118) Antibody
Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
PXN / Paxillin Rabbit anti-Human Polyclonal (pSer178) Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
PXN / Paxillin Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Pig, Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$299
PXN / Paxillin Rabbit anti-Human Polyclonal (aa456-472) Antibody
Chicken, Sheep, Bovine, Rat, Pig, Horse, Bat, Rabbit, Mouse, Guinea pig, Human, Monkey
ICC, IHC, IHC-Fr, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
PXN / Paxillin Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IP, WB
Unconjugated
100 µg/$341
PXN / Paxillin Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IP, WB
Unconjugated
100 µg/$341
PXN / Paxillin Mouse anti-Chicken Monoclonal Antibody
Chicken, Mouse, Dog, Rat, Human
ELISA, ICC, IHC, IP, WB
Unconjugated
100 µg/$1,022
PXN / Paxillin Rabbit anti-Human Polyclonal (Leu25) Antibody
Mouse, Rat, Human
IF, IHC, IHC-P, WB
Unconjugated
50 µl/$321; 100 µl/$403
PXN / Paxillin Mouse anti-Human Monoclonal Antibody
Chicken, Bovine, Mouse, Rat, Human
ELISA, ICC, IP, WB
Unconjugated
250 µg/$854
PXN / Paxillin Rabbit anti-Human Polyclonal (aa15-64) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
PXN / Paxillin Rabbit anti-Human Polyclonal (pTyr118) Antibody
Mouse, Rat, Human
ELISA, IF, WB
Unconjugated
100 µl/$689
PXN / Paxillin Rabbit anti-Human Polyclonal (Tyr118) Antibody
Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
PXN / Paxillin Rabbit anti-Human Polyclonal (Tyr118) (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
PXN / Paxillin Rabbit anti-Human Polyclonal (Tyr118) (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
PXN / Paxillin Rabbit anti-Human Polyclonal (Tyr118) (APC) Antibody
Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
PXN / Paxillin Rabbit anti-Human Polyclonal (Tyr118) (Azide-free) (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
PXN / Paxillin Rabbit anti-Human Polyclonal (Tyr118) (PE) Antibody
Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
PXN / Paxillin Rabbit anti-Human Polyclonal (10-90 aa) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
PXN / Paxillin Rabbit anti-Human Polyclonal (pTyr88) Antibody
Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
PXN / Paxillin Rabbit anti-Human Polyclonal (p31) Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$357
PXN / Paxillin Rabbit anti-Human Polyclonal (p118) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100 µg/$357
PXN / Paxillin Rabbit anti-Human Polyclonal (aa1-50) Antibody
Human
IHC, IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
PXN / Paxillin Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Pig, Human
IHC, IHC-P, WB
Unconjugated
30 µl/$263; 100 µl/$315; 200 µl/$379
PXN / Paxillin Mouse anti-Human Monoclonal (pTyr31) (1D4B) Antibody
Human
ICC, WB
Unconjugated
100 µg/$872
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