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SDC1 / Syndecan 1 / CD138
syndecan 1
SDC1 / Syndecan 1 / CD138 is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein.
| Gene Name: | syndecan 1 |
| Synonyms: | SDC1, CD138 antigen, SDC, SYND1, Syndecan, Syndecan 1, Syndecan-1, CD138, Syndecan proteoglycan 1 |
| Target Sequences: | NM_002997 NP_002988.3 P18827 |
Publications (3)
1
Increased CXCR3 Expression of Infiltrating Plasma Cells in Hunner Type Interstitial Cystitis. Akiyama Y, Morikawa T, Maeda D, Shintani Y, Niimi A, Nomiya A, Nakayama A, Igawa Y, Fukayama M, Homma Y. Scientific reports. 2016 6:28652. (IHC-P; Human)
[Full Text Article]
[PubMed:27339056]
[PMC:PMC4919639]
2
Halting the vicious cycle within the multiple myeloma ecosystem: blocking JAM-A on bone marrow endothelial cells restores the angiogenic homeostasis and suppresses tumor progression. Antonio G Solimando, Matteo C Da Vià, Patrizia Leone, Paola Borrelli, Giorgio A Croci, Paula Tabares, Andreas Brandl, Giuseppe Di Lernia, Francesco P Bianchi, Silvio Tafuri, Torsten Steinbrunn, Alessandra Balduini, Assunta Melaccio, Simona De Summa, Antonella Argentiero, Hilka Rauert-Wunderlich, Maria A Frassanito, Paolo Ditonno, Erik Henke, Wolfram Klapper, Roberto Ria, Carolina Terragna, Leo Rasche, Andreas Rosenwald, Martin K Kortüm, Michele Cavo, Domenico Ribatti, Vito Racanelli, Hermann Ein. Haematologica. 2020 April; [Full Text Article]
[PubMed:32354870]
[PMC:PMC8252928]
Related Antibodies: LS-B9360.
3
Acetyl-CoA Synthetase 2: A Critical Linkage in Obesity-Induced Tumorigenesis in Myeloma. Zongwei Li, Huan Liu, Jin He, Zhiqiang Wang, Zheng Yin, Gichun You, Zhiming Wang, Richard E Davis, Pei Lin, P Leif Bergsagel, Elisabet E Manasanch, Stephen T C Wong, Nestor F Esnaola, Jenny C Chang, Robert Z Orlowski, Qing Yi, Jing Yang. The Breast : official journal of the European Society of Mastology. 2021 January;33:78-93e7. [Full Text Article]
[PubMed:33406405]
[PMC:PMC7799390]
Related Antibodies: LS-B9360.
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(111)
Target
SDC1 / Syndecan 1 / CD138
(111)
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(26)
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(68)
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(1)
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(1)
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(1)
Publications
No
(110)
Yes
(1)
Cancer Pathology
Cancer
SDC1 / Syndecan 1 / CD138 Mouse anti-Human Monoclonal (B-A38) Antibody
Human
Flo, IF, IHC, IHC-Fr, IHC-P, WB
Unconjugated
0.05 mg/$460
SDC1 / Syndecan 1 / CD138 Mouse anti-Human Monoclonal (RPE) (B-A38) Antibody
Human
Flo
RPE Conjugated
100 Tests/$485
SDC1 / Syndecan 1 / CD138 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$485
SDC1 / Syndecan 1 / CD138 Mouse anti-Human Monoclonal (aa28-171) (1A3H4) Antibody
Human
ELISA, Flo, IF, IHC, WB
Unconjugated
0.1 mg/$447; 100 µl/$459
SDC1 / Syndecan 1 / CD138 Mouse anti-Human Monoclonal (aa210-238) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
0.05 ml/$460
SDC1 / Syndecan 1 / CD138 Mouse anti-Human Monoclonal Antibody
Human
ELISA, Flo, IHC, IHC-Fr, IHC-P
Unconjugated
50 µg/$485
SDC1 / Syndecan 1 / CD138 Mouse anti-Human Monoclonal (MI15) Antibody
Rat, Non-Human Primates, Human
Flo, IHC-P, IP, WB
Unconjugated
0.1 mg/$316
Cancer Pathology
Cancer
SDC1 / Syndecan 1 / CD138 Mouse anti-Human Monoclonal (Concentrated) Antibody
Human
ELISA, IHC-P
Unconjugated, Concentrated
0.05 ml/$460
SDC1 / Syndecan 1 / CD138 Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Rat, Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$485
SDC1 / Syndecan 1 / CD138 Rat anti-Human Monoclonal (aa18-251) Antibody
Human
ELISA, Flo, IHC
Unconjugated
100 µg/$962
SDC1 / Syndecan 1 / CD138 Rabbit anti-Human Polyclonal (aa83-132) Antibody
Rat, Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
SDC1 / Syndecan 1 / CD138 Rabbit anti-Human Monoclonal (PE) (017) Antibody
Human
Flo
PE Conjugated
25 Tests/$263; 100 Tests/$376
SDC1 / Syndecan 1 / CD138 Rabbit anti-Human Polyclonal (aa23-253) (FITC) Antibody
Human
WB
FITC Conjugated
100 µl/$341; 200 µl/$397; 500 µl/$583; 1 ml/$715; 2 ml/$953; 5 ml/$1,628
SDC1 / Syndecan 1 / CD138 Rabbit anti-Human Monoclonal (Preservative Free) (160) Antibody
Human
IHC-P
Unconjugated, Preservative Free
100 µl/$412
SDC1 / Syndecan 1 / CD138 Rabbit anti-Cow Polyclonal (aa47-305) (APC) Antibody
Bovine, Cow
WB
APC Conjugated
100 µl/$434; 200 µl/$529; 500 µl/$938; 1 ml/$1,108; 2 ml/$1,487; 5 ml/$2,787
SDC1 / Syndecan 1 / CD138 Mouse anti-Human Monoclonal Antibody
Human
ELISA, IHC, IHC-P, IP, WB
Unconjugated
500 µl/$680
SDC1 / Syndecan 1 / CD138 Rabbit anti-Rat Polyclonal (aa58-313) (FITC) Antibody
Rat
WB
FITC Conjugated
100 µl/$352; 200 µl/$413; 500 µl/$625; 1 ml/$780; 2 ml/$1,018; 5 ml/$1,775
SDC1 / Syndecan 1 / CD138 Rabbit anti-Human Polyclonal (aa23-254) Antibody
Human
ELISA, IF, IHC-P
Unconjugated
50 µg/$460
SDC1 / Syndecan 1 / CD138 Rabbit anti-Human Monoclonal (Preservative Free) (017) Antibody
Human
ELISA, Flo
Unconjugated, Preservative Free
100 µl/$412
SDC1 / Syndecan 1 / CD138 Mouse anti-Human Monoclonal (Biotin) (531CT15.4.1;531CT15.1.4) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
SDC1 / Syndecan 1 / CD138 Rabbit anti-Human Monoclonal (EP201) Antibody
Human
IHC
Unconjugated
6 ml/$456
SDC1 / Syndecan 1 / CD138 Rabbit anti-Human Monoclonal (EP201) Antibody
Human
IHC
Unconjugated
0.1 ml/$293; 0.5 ml/$538; 1 ml/$802
SDC1 / Syndecan 1 / CD138 Rabbit anti-Human Polyclonal (aa266-295) Antibody
Human
WB
Unconjugated
400 µl/$393
SDC1 / Syndecan 1 / CD138 Rabbit anti-Human Polyclonal (aa218-251) Antibody
Human
WB
Unconjugated
10 µg/$318; 100 µg/$470
SDC1 / Syndecan 1 / CD138 Rabbit anti-Human Monoclonal (Preservative Free) (001) Antibody
Human
ELISA
Unconjugated, Preservative Free
100 µl/$412
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