SIRPA / CD172a

signal-regulatory protein alpha

CD172A / SIRPA is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein can be phosphorylated by tyrosine kinases. The phospho-tyrosine residues of this PTP have been shown to recruit SH2 domain containing tyrosine phosphatases (PTP), and serve as substrates of PTPs. This protein was found to participate in signal transduction mediated by various growth factor receptors. CD47 has been demonstrated to be a ligand for this receptor protein. This gene and its product share very high similarity with several other members of the SIRP family. These related genes are located in close proximity to each other on chromosome 20p13. Multiple alternatively spliced transcript variants have been determined for this gene.

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Products

Proteins (35)

Type

Over-Expression Lysate (6)

Recombinant (29)

Target

SIRPA / CD172a (35)

Publications

No (35)

Tag

6His, C-terminus (6)

AVI-6His, C-terminus (1)

Fc, C-terminus (5)

GST (1)

His (2)

His, N-Terminal (2)

His,C-terminus (2)

His-SUMO (1)

His-T7 (2)

mFc, C-terminus (1)

Mouse IgG2a, C-terminus (2)

Myc-DDK (Flag) (9)

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Species

Cynomolgus (1)

Human (20)

Mouse (9)

Rat (2)

Source

293T Cells (3)

E. coli (6)

HEK 293 Cells (9)

Human (3)

Human Cells (6)

Mammalian Cells (7)

Wheat Germ Extract (1)

Purification

Purified (4)

Low Endotoxin Level

Low endotoxin level (19)

Biologically Active

Biologically active (4)

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Human SIRPA / CD172a Protein (Recombinant Fc, C-terminus) (Glu31-Arg370) - LS-G40300

Source:

Human Cells

Tag:

Fc, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

64.1kD

Price:

10 µg/$281; 50 µg/$395; 500 µg/$1,585; 1 mg/$2,157

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Human SIRPA / CD172a Protein (Recombinant His, N-Terminal) (aa105-324) - LS-G13139

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

28.1 kDa

Price:

10 µg/$262; 50 µg/$339; 100 µg/$512; 200 µg/$642; 1 mg/$1,623; 500 µg/$1,214; 5 mg/$2,562; 2 mg/$1,796

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Human SIRPA / CD172a Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G67930

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

52.3 kDa

Price:

20 µg/$1,107

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Human SIRPA / CD172a Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G67931

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

52.3 kDa

Price:

20 µg/$1,107

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Human SIRPA / CD172a Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G67933

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

52.3 kDa

Price:

20 µg/$1,107

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Mouse SIRPA / CD172a Protein (Recombinant His-T7) (aa56-296) - LS-G13140

Source:

E. coli

Tag:

His-T7

Molecular Weight:

30.6 kDa

Price:

10 µg/$276; 50 µg/$412; 100 µg/$657; 200 µg/$822; 1 mg/$1,905; 500 µg/$1,455; 5 mg/$2,871; 2 mg/$2,090

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Human SIRPA / CD172a Protein (Recombinant His-SUMO) (aa31-373) - LS-G21188

Source:

E. coli

Tag:

His-SUMO

Molecular Weight:

53.64 kD

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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Rat SIRPA / CD172a Protein (Recombinant His-T7) (aa116-308) - LS-G24170

Source:

E. coli

Tag:

His-T7

Molecular Weight:

25.0 kDa

Price:

10 µg/$281; 50 µg/$442; 100 µg/$705; 200 µg/$882; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176

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Human SIRPA / CD172a Protein (Recombinant GST) (Full Length) - LS-G36612

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

78.54 kDa

Price:

10 µg/$479; 25 µg/$670

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Human SIRPA / CD172a Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G81002

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

54.81 kDa

Price:

20 µg/$215

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Human SIRPA / CD172a Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G81004

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

54.81 kDa

Price:

20 µg/$215

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Human SIRPA / CD172a Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G81005

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

52.3 kDa

Price:

20 µg/$150

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SIRPA / CD172a Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G107780

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

52.3 kDa

Price:

100 µg/$494

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SIRPA / CD172a Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G120436

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

54.81 kDa

Price:

100 µg/$710

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SIRPA / CD172a Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G120438

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

54.81 kDa

Price:

100 µg/$710

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Human SIRPA / CD172a Protein (Recombinant AVI-6His, C-terminus) - LS-G146005

Source:

Human

Tag:

AVI-6His, C-terminus

Biological Activity:

Biologically active

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

39.9 kDa

Price:

20 µg/$416; 100 µg/$910

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Human SIRPA / CD172a Protein (Recombinant 6His, C-terminus) - LS-G146020

Source:

Human

Tag:

6His, C-terminus

Biological Activity:

Biologically active

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

38.1 kDa

Price:

10 µg/$273; 50 µg/$398

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Cynomolgus SIRPA / CD172a Protein (Recombinant 6His, C-terminus) - LS-G146311

Source:

Human

Tag:

6His, C-terminus

Biological Activity:

Biologically active

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

37.9 kDa

Price:

10 µg/$280; 50 µg/$419

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Human SIRPA / CD172a Protein (Recombinant 6His, C-terminus) - LS-G136771

Source:

Mammalian Cells

Tag:

6His, C-terminus

Biological Activity:

Biologically active

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

38.31 kDa

Price:

50 µg/$414; 10 µg/$279; 1 mg/$2,837; 500 µg/$1,987

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Mouse SIRPA / CD172a Protein (Recombinant Fc, C-terminus) (Met1-Asn373) - LS-G138131

Source:

HEK 293 Cells

Tag:

Fc, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

64.9 kDa

Price:

100 µg/$721

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Rat SIRPA / CD172a Protein (Recombinant His,C-terminus) (Met1-Asn373) - LS-G138208

Source:

HEK 293 Cells

Tag:

His,C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

39 kDa

Price:

100 µg/$721

Select

Human SIRPA / CD172a Protein (Recombinant Fc, C-terminus) (Glu31-Arg370) - LS-G139160

Source:

Mammalian Cells

Tag:

Fc, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

64.1 kDa

Price:

10 µg/$281; 50 µg/$389

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Mouse SIRPA / CD172a Protein (Recombinant Fc, C-terminus) (Lys32-Asn372) - LS-G139278

Source:

Mammalian Cells

Tag:

Fc, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

65.1 kDa

Price:

10 µg/$281; 50 µg/$389

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Mouse SIRPA / CD172a Protein (Recombinant Mouse IgG2a, C-terminus) (Lys32-Asn372) - LS-G139279

Source:

Mammalian Cells

Tag:

Mouse IgG2a, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

65.1 kDa

Price:

10 µg/$281; 50 µg/$389

Select

Human SIRPA / CD172a Protein (Recombinant mFc, C-terminus) (Glu31-Arg370) - LS-G139334

Source:

Mammalian Cells

Tag:

mFc, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

64.5 kDa

Price:

10 µg/$281; 50 µg/$389

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