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The N-terminal may be involved in transducing a signal required for tight junction assembly, while the C-terminal may have specific properties of tight junctions. The alpha domain might be involved in stabilizing junctions. Plays a role in the regulation of cell migration by targeting CDC42BPB to the leading edge of migrating cells.
Gene Name: | tight junction protein 1 |
Family/Subfamily: | Occludin , Not assigned-Occludin |
Synonyms: | TJP1, ZO-1, Zona occludens protein 1, Zona occludens 1, Zonula occludens protein 1, Tight junction protein 1, ZO1, Tight junction protein ZO-1, Zonula occludens 1 protein |
Target Sequences: | NM_003257 NP_003248.3 Q07157 |
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