TPSAB1 / Mast Cell Tryptase

Tryptase alpha/beta 1

Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. These genes are characterized by several distinct features. They have a highly conserved 3' UTR and contain tandem repeat sequences at the 5' flank and 3' UTR which are thought to play a role in regulation of the mRNA stability. These genes have an intron immediately upstream of the initiator Met codon, which separates the site of transcription initiation from protein coding sequence. This feature is characteristic of tryptases but is unusual in other genes. The alleles of this gene exhibit an unusual amount of sequence variation, such that the alleles were once thought to represent two separate genes, alpha and beta 1. Beta tryptases appear to be the main isoenzymes expressed in mast cells; whereas in basophils, alpha tryptases predominate. Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and inflammatory disorders.

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Products

ELISA Kits (14)

Type

Competitive EIA (6)

Development Kit (1)

Sandwich (7)

Target

TPSAB1 / Mast Cell Tryptase (14)

Reactivity

Human (6)

Mouse (2)

Rat (5)

Guinea pig (1)

Product Group

DevKit DuoPlus (1)

Format

96-Well Strip Plate (13)

Antibody Pair and Standard (1)

Publications

No (13)

Yes (1)

Sample Type

Cell Culture Supernatants (4)

Cell Lysates (1)

Plasma (14)

Serum (14)

Tissue Homogenates (5)

Urine (1)

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Rat TPSAB1 / Mast Cell Tryptase (Sandwich ELISA) ELISA Kit - LS-F12863

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.78 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$669

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Human TPSAB1 / Mast Cell Tryptase (Sandwich ELISA) ELISA Kit - LS-F13484

(4.0) Rating

(1) Publication(s)

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$783

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Mouse TPSAB1 / Mast Cell Tryptase (Sandwich ELISA) ELISA Kit - LS-F15881

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$783

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Human TPSAB1 / Mast Cell Tryptase (Sandwich ELISA) ELISA Kit - LS-F39656

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

156 - 10000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum

Price:

1 Plate/$632

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Rat TPSAB1 / Mast Cell Tryptase (Competitive EIA) ELISA Kit - LS-F28097

Type:

Competitive EIA

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.5 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$805

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Rat TPSAB1 / Mast Cell Tryptase (Competitive EIA) ELISA Kit - LS-F28022

Type:

Competitive EIA

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.5 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$805

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Rat TPSAB1 / Mast Cell Tryptase (Sandwich ELISA) ELISA Kit - LS-F32652

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.781 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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Human TPSAB1 / Mast Cell Tryptase (Competitive EIA) ELISA Kit - LS-F27743

Type:

Competitive EIA

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

2.5 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$805

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Human TPSAB1 / Mast Cell Tryptase (Sandwich ELISA) ELISA Kit - LS-F32653

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

1.56 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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DevKit DuoPlus Human TPSAB1 / Mast Cell Tryptase ELISA Development Kit - LS-F71765

Type:

Development Kit

Format:

Antibody Pair and Standard

Reactivity:

Human

Range:

15.6 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

500 Wells/$1,229; 1000 Wells/$1,826

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Human TPSAB1 / Mast Cell Tryptase (Competitive EIA) ELISA Kit - LS-F27832

Type:

Competitive EIA

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

1 - 25 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$805

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Mouse TPSAB1 / Mast Cell Tryptase (Competitive EIA) ELISA Kit - LS-F28642

Type:

Competitive EIA

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

1 - 25 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$805

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Guinea pig TPSAB1 / Mast Cell Tryptase (Competitive EIA) ELISA Kit - LS-F28123

Type:

Competitive EIA

Format:

96-Well Strip Plate

Reactivity:

Guinea pig

Range:

1 - 25 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$805

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Rat TPSAB1 / Mast Cell Tryptase (Sandwich ELISA) ELISA Kit - LS-F53891

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.625 - 40 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Urine

Price:

1 Plate/$968

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