WNK1

WNK lysine deficient protein kinase 1

Serine/threonine kinase which plays an important role in the regulation of electrolyte homeostasis, cell signaling, survival, and proliferation. Acts as an activator and inhibitor of sodium-coupled chloride cotransporters and potassium-coupled chloride cotransporters respectively. Activates SCNN1A, SCNN1B, SCNN1D and SGK1. Controls sodium and chloride ion transport by inhibiting the activity of WNK4, by either phosphorylating the kinase or via an interaction between WNK4 and the autoinhibitory domain of WNK1. WNK4 regulates the activity of the thiazide-sensitive Na-Cl cotransporter, SLC12A3, by phosphorylation. WNK1 may also play a role in actin cytoskeletal reorganization. Phosphorylates NEDD4L.

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Products

Antibodies (55)

Type

Primary (55)

Target

WNK1 (55)

Reactivity

Human (55)

Mouse (27)

Rat (19)

Bat (2)

Bovine (1)

Chicken (1)

Hamster (2)

Horse (2)

Monkey (4)

Pig (11)

Rabbit (2)

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Application

IHC (30)

IHC-P (12)

WB (42)

ELISA (25)

ICC (1)

IF (7)

IP (2)

Peptide-ELISA (4)

Host

rabbit (55)

Product Group

IHCPlus (2)

PathPlus Cancer (2)

Isotype

IgG (33)

Clonality

polyclonal pc (55)

Format

APC (1)

APC Conjugated (3)

Biotin Conjugated (4)

Cy3 Conjugated (1)

Cy7 Conjugated (1)

FITC Conjugated (4)

HRP Conjugated (4)

PE Conjugated (3)

Unconjugated (35)

Epitope

C-Terminus (9)

Internal (8)

aa1954-2231 (8)

N-Terminus (4)

pThr58 (4)

40-120 aa (2)

Tyr52 (1)

aa1625-1675 (1)

aa2100-2150 (1)

aa24-73 (1)

aa80-338 (1)

p58 (1)

pThr60 (1)

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Publications

No (55)

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PathPlus™ WNK1 Antibody (Internal) LS-A7494

Cancer

Fast Shipping

(5.0) Rating

Antibody:

WNK1 Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Human, Monkey

Applications:

IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$460

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IHC-plus™ WNK1 Antibody (Internal) LS-A7484

Fast Shipping

(4.0) Rating

Antibody:

WNK1 Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Chicken, Bovine, Rat, Hamster, Pig, Horse, Bat, Rabbit, Mouse, Human, Monkey

Applications:

ELISA, IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$460

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PathPlus™ WNK1 Antibody (C-Terminus) LS-A7959

Cancer

Fast Shipping

(5.0) Rating

Antibody:

WNK1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Rabbit, Mouse, Rat, Hamster, Horse, Bat, Human, Monkey

Applications:

IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$460

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WNK1 Antibody (phospho-Thr60) LS-C192172

Antibody:

WNK1 Rabbit anti-Human Polyclonal (pThr60) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$328; 100 µl/$419

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WNK1 Antibody (aa24-73) LS-C117584

Antibody:

WNK1 Rabbit anti-Human Polyclonal (aa24-73) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

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WNK1 Antibody LS-C332174

Antibody:

WNK1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IF, IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

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IHC-plus™ WNK1 Antibody (aa1625-1675) LS-B15287

(4.0) Rating

Antibody:

WNK1 Rabbit anti-Human Polyclonal (aa1625-1675) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, IP, WB

Format:

Unconjugated

Price:

50 µl/$460

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WNK1 Antibody (aa80-338) LS-C178509

Antibody:

WNK1 Rabbit anti-Human Polyclonal (aa80-338) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$332

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WNK1 Antibody (N-Terminus) LS-C11063

Antibody:

WNK1 Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$832

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WNK1 Antibody (phospho-Thr58) LS-C801232

Antibody:

WNK1 Rabbit anti-Human Polyclonal (pThr58) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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WNK1 Antibody LS-C801670

Antibody:

WNK1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Select

WNK1 Antibody LS-C502040

Antibody:

WNK1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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WNK1 Antibody (N-Terminus) LS-C11065

Antibody:

WNK1 Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Human, Monkey

Applications:

ICC, IF, WB

Format:

Unconjugated

Price:

100 µl/$688

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WNK1 Antibody (phospho-Thr58) LS-C199735

Antibody:

WNK1 Rabbit anti-Human Polyclonal (pThr58) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

Select

WNK1 Antibody LS-C490671

Antibody:

WNK1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µg/$575

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WNK1 Antibody LS-C662436

Antibody:

WNK1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

10 µg/$318; 100 µg/$470

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WNK1 Antibody LS-C666243

Antibody:

WNK1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$351

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WNK1 Antibody (40-120 aa) LS-C381215

Antibody:

WNK1 Rabbit anti-Human Polyclonal (40-120 aa) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

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WNK1 Antibody (40-120 aa) LS-C386676

Antibody:

WNK1 Rabbit anti-Human Polyclonal (40-120 aa) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

Select

WNK1 Antibody (phospho-Thr58) LS-C827112

Antibody:

WNK1 Rabbit anti-Human Polyclonal (pThr58) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$357

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WNK1 Antibody (p58) LS-C825871

Antibody:

WNK1 Rabbit anti-Human Polyclonal (p58) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$357

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WNK1 Antibody (Tyr52) LS-C176254

Antibody:

WNK1 Rabbit anti-Human Polyclonal (Tyr52) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$321; 100 µl/$403

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WNK1 Antibody (N-Terminus) LS-C358395

Antibody:

WNK1 Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Mouse, Rat, Pig, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$315

Select

WNK1 Antibody (N-Terminus) LS-C358398

Antibody:

WNK1 Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Mouse, Rat, Pig, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$299

Select

WNK1 Antibody (C-Terminus) LS-C330738

Antibody:

WNK1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

200 µl/$734

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