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Catalog Number Size Price
LS-C148242-50 50 µl $386 
CASP3 / Caspase 3 Antibody - Formalin-fixed, paraffin-embedded section of irradiated mouse spleen stained for Active/Cleaved Caspase-3 expression using Polyclonal Antibody to Active/Cleaved Caspase-3 at 1:2000. Staining is seen in the nuclei of a subset of the cell population. Caspase-3 expression in the nucleus is considered to be a marker of active/caspase-3 expression and apoptosis. Hematoxylin-Eos in counterstain.
CASP3 / Caspase 3 Antibody - Formalin-fixed, paraffin-embedded section of dog ischemic brain stained for Active/Cleaved Caspase-3 expression using Polyclonal Antibody to Active/Cleaved Caspase-3 at 1:2000. Staining is seen in the nuclei of dying neurons (black arrow) but not in the morphologically normal nuclei (open arrows). Caspase-3 expression in the nucleus is considered to be a marker of active/caspase-3 expression and apoptosis. Hematoxylin-Eosin counterstain.
CASP3 / Caspase 3 Antibody - Formalin-fixed, paraffin-embedded section of irradiated mouse spleen stained for Active/Cleaved Caspase-3 expression using Polyclonal Antibody to Active/Cleaved Caspase-3 at 1:2000. Staining is seen in the nuclei of a subset of the cell population. Caspase-3 expression in the nucleus is considered to be a marker of active/caspase-3 expression and apoptosis. Hematoxylin-Eos in counterstain.
CASP3 / Caspase 3 Antibody - Formalin-fixed, paraffin-embedded section of dog ischemic brain stained for Active/Cleaved Caspase-3 expression using Polyclonal Antibody to Active/Cleaved Caspase-3 at 1:2000. Staining is seen in the nuclei of dying neurons (black arrow) but not in the morphologically normal nuclei (open arrows). Caspase-3 expression in the nucleus is considered to be a marker of active/caspase-3 expression and apoptosis. Hematoxylin-Eosin counterstain.
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Polyclonal Rabbit anti‑Human CASP3 / Caspase 3 Antibody (IHC, WB) LS‑C148242

Polyclonal Rabbit anti‑Human CASP3 / Caspase 3 Antibody (IHC, WB) LS‑C148242

Antibody:
CASP3 / Caspase 3 Rabbit anti-Human Polyclonal Antibody
Application:
IHC, IHC-P, IHC-Fr, WB, IP
Reactivity:
Human, Mouse, Rat, Gerbil
Format:
Unconjugated, Unmodified
Price
Catalog Number
$386
LS-C148242-50
Toll Free North America
(800) 227-6666
For Research Use Only

Overview

Antibody:
CASP3 / Caspase 3 Rabbit anti-Human Polyclonal Antibody
Application:
IHC, IHC-P, IHC-Fr, WB, IP
Reactivity:
Human, Mouse, Rat, Gerbil
Format:
Unconjugated, Unmodified

Specifications

Description
Caspase 3 antibody LS-C148242 is an unconjugated rabbit polyclonal antibody to Caspase 3 (CASP3) from human. It is reactive with human, mouse, rat and other species. Validated for IHC, IP and WB. Cited in 1 publication.
Target
Human CASP3 / Caspase 3
Synonyms
CASP3 | Apopain | CASP-3 | Caspase-3 | CPP32B | CPP32 | Cysteine protease CPP32 | SCA-1 | SREBP cleavage activity 1 | Yama | Procaspase3 | Caspase 3 | CPP-32 | PARP cleavage protease | Protein Yama
Host
Rabbit
Reactivity
Human, Mouse, Rat, Gerbil (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Antiserum
Modifications
Unmodified
Immunogen
Recombinant catalytically active human caspase-3 protein.
Specificity
Preferentially detects active caspase-3 (large subunit: ~14-21 kD, and small subunit: ~10 kD). However, it may also detect pro-caspase-3 (~32 kD) in some cell or tissue systems. Nuclear immunostaining of caspase-3 is considered be an indication of active/cleaved caspase-3.
Applications
  • IHC
  • IHC - Paraffin (1:1000 - 1:5000)
  • IHC - Frozen
  • Western blot (1:1000 - 1:2000)
  • Immunoprecipitation (1:50 - 1:200)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Presentation
Antiserum, 0.05% sodium azide
Storage
Store at -20°C. Aliquot to avoid freeze/thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About CASP3 / Caspase 3
P42574 NM_004346 NP_004337.2

LSBio Ratings

CASP3 / Caspase 3 Antibody for IHC, WB/Western, IP LS-C148242 has an LSBio Rating of
Publications (4)

Publications (1)

In-frame deletion in canine PITRM1 is associated with a severe early-onset epilepsy, mitochondrial dysfunction and neurodegeneration10<sup> Research Programs Unit, Stem Cells and Metabolism Research Program, University of Helsinki, Helsinki, Finland12<sup> Department of Neurology, Neuro-SysMed, Haukeland University Hospital, Bergen, Norway14<sup> Folkhälsan Research Center, Helsinki, Finland. hannes.lohi@helsinki.fi. Marjo K Hytönen , Riika Sarviaho , Christopher B Jackson, Pernilla Syrjä, Tarja Jokinen , Kaspar Matiasek, Marco Rosati, Cristina Dallabona, Enrico Baruffini, Ileana Quintero , Meharji Arumilli , Geoffray Monteuuis, Jonas Donner, Marjukka Anttila, Anu Suomalainen, Laurence A Bindoff , Hannes Lohi. Human genetics. 2021 Nov;;140:1593-1609.

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Date Requested: 11/21/2024