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| Catalog Number | Size | Price |
|---|---|---|
| LS-B477-50 | 50 µg (1 mg/ml) | $460 |
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IHC‑plus™ Polyclonal Rabbit anti‑Human CASP6 / Caspase 6 Antibody (IHC, IF, WB) LS‑B477
IHC‑plus™ Polyclonal Rabbit anti‑Human CASP6 / Caspase 6 Antibody (IHC, IF, WB) LS‑B477
Note: This antibody replaces LS-C19499, LS-C187443
Antibody:
CASP6 / Caspase 6 Rabbit anti-Human Polyclonal Antibody
Application:
IHC, IHC-P, ICC, IF, WB, ELISA
Reactivity:
Human
Format:
Unconjugated, Unmodified
Toll Free North America
(800) 227-6666
(800) 227-6666For Research Use Only
Overview
Antibody:
CASP6 / Caspase 6 Rabbit anti-Human Polyclonal Antibody
Application:
IHC, IHC-P, ICC, IF, WB, ELISA
Reactivity:
Human
Format:
Unconjugated, Unmodified
Specifications
Description
Caspase 6 antibody LS-B477 is an unconjugated rabbit polyclonal antibody to human Caspase 6 (CASP6). Validated for ELISA, ICC, IF, IHC and WB. Tested on 20 paraffin-embedded human tissues. Cited in 3 publications.
Target
Human CASP6 / Caspase 6
Synonyms
CASP6 | Apoptotic protease Mch-2 | Caspase 6 | CASP-6 | Caspase-6 | Mch-2 | MCH2
Host
Rabbit
Reactivity
Human
(tested or 100% immunogen sequence identity)
Non-Reactivity
Mouse, Rat
Clonality
IgG
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
A 15 AA synthetic peptide near the center of human Caspase-6. The immunogen is located within aa 160-210 of Caspase-6.
Specificity
Depending on cell lines or tissues used, either full-length or other cleavage products may be observed.
Applications
- IHC
- IHC - Paraffin (2.5 µg/ml)
- ICC
- Immunofluorescence
- Western blot (1 µg/ml)
- ELISA
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Usage
Casp-6 antibody can be used for the detection of Caspase-6 by Western blot at 1 and 2 ug/mL. Antibody can also be used for immunocytochemistry starting at 1 ug/mL. For immunofluorescence start at 10 ug/mL. Antibody validated: Western Blot in human samples; Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Western Blot:
Presentation
PBS containing 0.02% Sodium Azide
Storage
Store at 4°C for up 3 months. Store at -20°C for up to 1 year. Avoid freeze/thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About CASP6 / Caspase 6
Validation
Anti-Caspase 6 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Anti-Caspase 6 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
See More About...
LSBio Ratings
IHC-plus™ CASP6 / Caspase 6 Antibody for IHC, ICC, IF/Immunofluorescence, WB/Western, ELISA LS-B477 has an LSBio Rating of
Publications (4.2)
Laboratory Validation Score (4)
Learn more about The LSBio Ratings Algorithm
Publications (3)
Caspase-6 activity in the CA1 region of the hippocampus induces age-dependent memory impairment. LeBlanc AC, Ramcharitar J, Afonso V, Hamel E, Bennett DA, Pakavathkumar P, Albrecht S. Cell death and differentiation. 2014 21:696-706. (ICC; Human)
Methylene blue inhibits Caspase-6 activity, and reverses Caspase-6-induced cognitive impairment and neuroinflammation in aged mice. Libin Zhou, Joseph Flores, Anastasia Noël, Olivier Beauchet, P Jesper Sjöström, Andrea C LeBlanc. Acta neuropathologica communications. 2019 Dec;7:210.
Caspase-6-cleaved Tau fails to induce Tau hyperphosphorylation and aggregation, neurodegeneration, glial inflammation, and cognitive deficits. Anastasia Noël , Bénédicte Foveau , Andréa C LeBlanc. Cell death & disease. 2021 Mar;12:227.
Customer Reviews (0)
Featured Products
Species:
Mouse, Human, Rabbit
Applications:
IHC, IHC - Paraffin, Western blot, ELISA
Species:
Mouse, Rat
Applications:
IHC, Western blot, ELISA
Species:
Human, Monkey, Mouse, Rat, Horse, Pig, Rabbit
Applications:
Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Species:
Human
Applications:
IHC, IHC - Paraffin, Western blot
Species:
Human, Monkey, Mouse, Rat, Bovine
Applications:
IHC, IHC - Paraffin, ICC, Immunofluorescence, Western blot
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 12/24/2024
Date Requested: 12/24/2024
