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Catalog Number Size Price
LS-C187726-0.1 0.1 mg (1.41 mg/ml) $395 
Antibody

Polyclonal Sheep anti‑Rat EDNRB / Endothelin B Receptor Antibody (aa424‑437, IHC, IF) LS‑C187726

Polyclonal Sheep anti‑Rat EDNRB / Endothelin B Receptor Antibody (aa424‑437, IHC, IF) LS‑C187726

Antibody:
EDNRB / Endothelin B Receptor Sheep anti-Rat Polyclonal (aa424-437) Antibody
Application:
IHC, IHC-P, IF, IP
Reactivity:
Rat
Format:
Unconjugated, Unmodified
Price
Catalog Number
$395
LS-C187726-0.1
Toll Free North America
206-374-1102
For Research Use Only

Overview

Antibody:
EDNRB / Endothelin B Receptor Sheep anti-Rat Polyclonal (aa424-437) Antibody
Application:
IHC, IHC-P, IF, IP
Reactivity:
Rat
Format:
Unconjugated, Unmodified

Specifications

Description
Endothelin B Receptor antibody LS-C187726 is an unconjugated sheep polyclonal antibody to rat Endothelin B Receptor (EDNRB) (aa424-437). Validated for IF, IHC and IP.
Target
Rat EDNRB / Endothelin B Receptor
Synonyms
EDNRB | ABCDS | Endothelin B receptor | Etb receptor | ET-B | Et-b receptor | Et-b-r | ET-RB | ETBR | ETRB | Etb-svr | WS4A | Endothelin receptor type B | ET-BR | ETB | HSCR | HSCR2
Host
Sheep
Reactivity
Rat (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Affinity purified
Modifications
Unmodified
Immunogen
Keyhole limpet hemocyanin (KLH) conjugated C-Terminus peptide KANDHGYDNFRSSNN corresponding to amino acids 424 to 437 of rat endothelin B receptor. Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Galago, Marmoset, Mouse, Rat, Ferret, Sheep, Goat, Hamster, Elephant, Panda, Cat, Bovine, Dog, Horse, Rabbit, Pig, Opossum, Zebra finch, Chicken, Platypus (93%); Lizard (87%).
Epitope
aa424-437
Specificity
Recognizes an epitope within the C-terminal (CT) region of endothelin B receptor (ET-B), a widely distributed transmembrane protein and member of the G-protein coupled receptor 1 family, which acts as a non-specific receptor for endothelin 1, 2, and 3, and mediates its action by G protein association and activation of a phosphatidylinositol-calcium second messenger system. AAR43 recognizes epitopes on the cytoplasmic side of the receptor and therefore the cell membrane must be permeable to the antibody. AAR43 does not block the binding of endothelins. AAR43 is reported as suitable for use in immunocytochemistry on acetone fixed cells.
Applications
  • IHC
  • IHC - Paraffin (10 - 20 µg/ml)
  • Immunofluorescence (10 - 20 µg/ml)
  • Immunoprecipitation (20 - 40 µg/ml)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Presentation
PBS, less than 0.1% Sodium Azide
Storage
Store at 4°C. Do not freeze. Store undiluted. Microcentrifugation recommended if solution contains precipitate.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About EDNRB / Endothelin B Receptor
P24530 NM_000115 NP_000106.1

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Requested From: United States
Date Requested: 7/22/2024