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EDNRB / Endothelin B Receptor
endothelin receptor type B
The Endothelin Receptor ETB is expressed in most tissues. Mutations of the receptor gene are responsible for Hirschsprung disease type 2, a multigenic disorder with phenotypes such as bicolored irides, megacolon, hypopigmentation, and hearing loss. The ETB receptor has similar affinity for all three endothelins and activates a phosphatidylinositol-calcium second messenger system. A splice variant, termed SVR, has been described; the sequence of the ETB-SVR receptor is identical to ET-B receptor, with the exception of the intracellular C-terminal domain. While both splice variants bind endothelin ET1, they exhibit different responses, which suggests that they may be functionally distinct.
| Gene Name: | endothelin receptor type B |
| Family/Subfamily: | GPCR , Endothelin |
| Synonyms: | EDNRB, ABCDS, Endothelin B receptor, Etb receptor, ET-B, Et-b receptor, Et-b-r, ET-RB, ETBR, ETRB, Etb-svr, WS4A, Endothelin receptor type B, ET-BR, ETB, HSCR, HSCR2 |
| Target Sequences: | NM_000115 NP_000106.1 P24530 |
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Neuroscience
EDNRB / Endothelin B Receptor Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Dog, Human
ICC, IHC, IHC-P, WB
Unconjugated
50 µg/$440
Fast Shipping
EDNRB / Endothelin B Receptor Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Dog, Human
IHC, IHC-P, WB
Unconjugated
50 µg/$440
Fast Shipping
EDNRB / Endothelin B Receptor Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Rabbit, Mouse, Goat, Dog, Bovine, Rat, Hamster, Pig, Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$440
EDNRB / Endothelin B Receptor Rabbit anti-Human Polyclonal (aa409-439) Antibody
Mouse, Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
200 µl/$460
EDNRB / Endothelin B Receptor Sheep anti-Human Polyclonal (aa27-101) Antibody
Human
ELISA, Flo, WB
Unconjugated
100 µg/$930
EDNRB / Endothelin B Receptor Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
500 µg/$393
EDNRB / Endothelin B Receptor Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$294; 100 µg/$360
EDNRB / Endothelin B Receptor Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
EDNRB / Endothelin B Receptor Sheep anti-Rat Polyclonal (aa424-437) Antibody
Rat
IF, IHC, IHC-P, IP
Unconjugated
0.1 mg/$395
EDNRB / Endothelin B Receptor Rabbit anti-Human Polyclonal (Internal) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µg/$380
EDNRB / Endothelin B Receptor Sheep anti-Rat Polyclonal (C-Terminus) Antibody
Mouse, Rat, Human
IHC, IP
Unconjugated
250 µg/$451
EDNRB / Endothelin B Receptor Rabbit anti-Human Polyclonal Antibody
Human
ELISA, Flo, IHC, WB
Unconjugated
100 µg/$351
Sandwich
96-Well Strip Plate
Mouse
78 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
EDNRB / Endothelin B Receptor Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
100 µg/$575
EDNRB / Endothelin B Receptor Rabbit anti-Human Polyclonal (aa406-439) Antibody
Rabbit, Mouse, Goat, Dog, Guinea pig, Sheep, Bovine, Rat, Pig, Human
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
EDNRB / Endothelin B Receptor Sheep anti-Rat Polyclonal (HRP) Antibody
Mouse, Sheep, Rat, Human
IF, IHC, IP, WB
HRP Conjugated
100 µl/$1,027
EDNRB / Endothelin B Receptor Sheep anti-Rat Polyclonal (Biotin) Antibody
Mouse, Sheep, Rat, Human
IF, IHC, IP, WB
Biotin Conjugated
100 µl/$1,027
EDNRB / Endothelin B Receptor Sheep anti-Rat Polyclonal (FITC) Antibody
Mouse, Sheep, Rat, Human
IF, IHC, IP, WB
FITC Conjugated
100 µl/$1,027
EDNRB / Endothelin B Receptor Sheep anti-Rat Polyclonal (APC) Antibody
Mouse, Sheep, Rat, Human
IF, IHC, IP, WB
APC Conjugated
100 µl/$1,027
EDNRB / Endothelin B Receptor Sheep anti-Rat Polyclonal (PE) Antibody
Mouse, Sheep, Rat, Human
IF, IHC, IP, WB
PE Conjugated
100 µl/$1,027
EDNRB / Endothelin B Receptor Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
EDNRB / Endothelin B Receptor Rabbit anti-Human Polyclonal Antibody
Human
IHC, WB
Unconjugated
50 µl/$356; 100 µl/$461
EDNRB / Endothelin B Receptor Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
EDNRB / Endothelin B Receptor Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$357
EDNRB / Endothelin B Receptor Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
20 µl/$275; 100 µl/$389
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