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Catalog Number Size Price
LS-C6611-100 100 µg $845 
Antibody

Monoclonal Mouse anti‑Human EGFR Antibody (phospho‑Tyr1173, WB) LS‑C6611

Monoclonal Mouse anti‑Human EGFR Antibody (phospho‑Tyr1173, WB) LS‑C6611

Antibody:
EGFR Mouse anti-Human Monoclonal (pTyr1173) Antibody
Application:
WB, IP, ELISA
Reactivity:
Human, Mouse, Rat, Dog
Format:
Unconjugated, Unmodified
Price
Catalog Number
$845
LS-C6611-100
Toll Free North America
(800) 227-6666
For Research Use Only

Overview

Antibody:
EGFR Mouse anti-Human Monoclonal (pTyr1173) Antibody
Application:
WB, IP, ELISA
Reactivity:
Human, Mouse, Rat, Dog
Format:
Unconjugated, Unmodified

Specifications

Description
EGFR antibody LS-C6611 is an unconjugated mouse monoclonal antibody to EGFR (pTyr1173) from human. It is reactive with human, mouse, rat and other species. Validated for ELISA, IP and WB. Cited in 2 publications.
Target
Human EGFR
Synonyms
EGFR | EGF Receptor | ERBB | ERBB1 | MENA | PIG61 | Proto-oncogene c-ErbB-1 | V-erb-b homolog | EGF-R | HER1
Host
Mouse
Reactivity
Human, Mouse, Rat, Dog (tested or 100% immunogen sequence identity)
Clonality
IgG1 Monoclonal
Conjugations
Unconjugated
Purification
Gel filtration
Modifications
Unmodified
Immunogen
Synthetic peptide corresponding to aa 1170-1176 (N1170AEpYLRV1176) of EGFR (epidermal growth factor receptor) phosphorylated at Tyr1173.
Epitope
pTyr1173
Specificity
Recognizes the N1170AEpYLRV motif corresponding to the major autophosphorylation site of human EGF receptor. Does not cross-react with the non-phosphorylated human, mouse, rat and dog EGF receptor or with unrelated Tyr-phosphorylated proteins. Species cross-reactivity: mouse.
Applications
  • Western blot (1 µg/ml)
  • Immunoprecipitation (1 - 10 µg/10E6 cells)
  • ELISA (0.05 µg/ml)
Usage
WB: For AP/BCIP/NBT (MTT) Detection:1 ug/ml. For HRPO/ECL deterction: 0.1 ug/ml. Use 0.5% Caseine, 0.5% BSA in PBST for blocking.
Presentation
PBS, 0.09% Sodium Azide, 40% Glycerol, Sucrose, PEG
Storage
Short term: store at 4°C. Long term: store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About EGFR
P00533 NM_005228 NP_005219.2

LSBio Ratings

EGFR Antibody (phospho-Tyr1173) for WB/Western, IP, ELISA LS-C6611 has an LSBio Rating of
Publications (4.1)

Publications (2)

Dasatinib and Doxorubicin Treatment of Sarcoma Initiating Cells: A Possible New Treatment Strategy. Aggerholm-Pedersen N, Demuth C, Safwat A, Meldgaard P, Kassem M, Sandahl Sorensen B. Stem cells international. 2016 2016:9601493. (WB; Human)

Increased PD-L1 expression in erlotinib-resistant NSCLC cells with MET gene amplification is reversed upon MET-TKI treatment. Christina Demuth, Morten Nørgaard Andersen, Kristine Raaby Jakobsen, Anne Tranberg Madsen, Boe Sandahl Sørensen. Oncotarget. 2017 September;8:68221-68229.

Customer Reviews (0)


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Requested From: United States
Date Requested: 12/22/2024