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| Catalog Number | Size | Price |
|---|---|---|
| LS-B13912-50 | 50 µl (0.5 mg/ml) | $460 |
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PathPlus™ Polyclonal Rabbit anti‑Human CX3CL1 / Fractalkine Antibody (aa25‑332, IHC, WB) LS‑B13912
PathPlus™ Polyclonal Rabbit anti‑Human CX3CL1 / Fractalkine Antibody (aa25‑332, IHC, WB) LS‑B13912
Note: This antibody replaces LS-C293300
Antibody:
CX3CL1 / Fractalkine Rabbit anti-Human Polyclonal (aa25-332) Antibody
Application:
IHC, IHC-P, WB
Reactivity:
Human, Mouse
Format:
Unconjugated, Unmodified
Toll Free North America
(800) 227-6666
(800) 227-6666For Research Use Only
Overview
Antibody:
CX3CL1 / Fractalkine Rabbit anti-Human Polyclonal (aa25-332) Antibody
Application:
IHC, IHC-P, WB
Reactivity:
Human, Mouse
Format:
Unconjugated, Unmodified
Specifications
Description
Fractalkine (CX3CL1) is a chemokine with a unique CX3C motif. Fractalkine is synthesized in endothelial cells as a membrane protein, and the N-terminal domain containing a CX3C motif is cleaved and secreted. Fractalkine is the first described cell-surface anchored chemokine and has potent mononuclear cell-directed adhesion and chemotactic properties. Fractalkine is involved in the pathogenesis of various chronic inflammatory diseases, such as rheumatoid arthritis and atherosclerosis.
References: The UniProt Consortium. Nucleic Acids Res. 47: D506-515 (2019); Nucleic Acids Res. 2016 Jan 4;44(D1):D733-45, PMID:26553804
Target
Human CX3CL1 / Fractalkine
Synonyms
CX3CL1 | ABCD-3 | C-X3-C motif chemokine 1 | C3Xkine | Chemokine ntt | CXC3C | FKN | Fractalkine | Neurotactin | CXC3 | NTN | SCYD1 | Small-inducible cytokine D1
Host
Rabbit
Reactivity
Human, Mouse
(tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Modifications
Unmodified
Immunogen
Recombinant CX3CL1 (Gln25-Pro332) expressed in E. coli.
Epitope
aa25-332
Specificity
The antibody is a rabbit polyclonal antibody raised against CX3CL1.
Applications
- IHC
- IHC - Paraffin (5 µg/ml)
- Western blot
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Usage
ICC 5-20ug/mL; IHCP 20 ug/ml; WB 0.5-5ug/mL;
Presentation
PBS, pH 7.4, 0.02% Sodium Azide, 50% Glycerol
Storage
Avoid repeated freeze/thaw cycles. Store at 4°C for frequent use. Aliquot and store at -20°C for 12 months.
Restrictions
For research use only. Intended for use by laboratory professionals.
About CX3CL1 / Fractalkine
Validation
Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE). This image was taken for the unconjugated form of this product. Other forms have not been tested.
Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE). This image was taken for the unconjugated form of this product. Other forms have not been tested.
Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE). This image was taken for the unconjugated form of this product. Other forms have not been tested.
Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE). This image was taken for the unconjugated form of this product. Other forms have not been tested.
See More About...
LSBio Ratings
PathPlus™ CX3CL1 / Fractalkine Antibody (aa25-332) for IHC, WB/Western LS-B13912 has an LSBio Rating of
Laboratory Validation Score (5)
Learn more about The LSBio Ratings Algorithm
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Featured Products
Species:
Human
Applications:
IHC, IHC - Paraffin, Western blot, ELISA
Species:
Human
Applications:
IHC - Paraffin, ELISA
Species:
Human
Applications:
IHC, IHC - Paraffin, Western blot, ELISA
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 12/22/2024
Date Requested: 12/22/2024
