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| Catalog Number | Size | Price |
|---|---|---|
| LS-B16150-50 | 50 µl (1 mg/ml) | $460 |
PathPlus™ Monoclonal Mouse anti‑Human GFAP Antibody (clone ABT‑GFAP, IHC) LS‑B16150
PathPlus™ Monoclonal Mouse anti‑Human GFAP Antibody (clone ABT‑GFAP, IHC) LS‑B16150
Note: This antibody replaces LS-C744518
Antibody:
GFAP Mouse anti-Human Monoclonal (ABT-GFAP) Antibody
Application:
IHC, IHC-P
Reactivity:
Human
Format:
Unconjugated, Unmodified
Toll Free North America
(800) 227-6666
(800) 227-6666For Research Use Only
Overview
Antibody:
GFAP Mouse anti-Human Monoclonal (ABT-GFAP) Antibody
Application:
IHC, IHC-P
Reactivity:
Human
Format:
Unconjugated, Unmodified
Specifications
Description
GFAP (glial fibrillary acidic protein) is an intermediate filament protein found in the central nervous system. Functionally, GFAP helps maintain cell shape and astrocyte mechanical strength, as well as participate in cell communication and blood brain barrier function. In immunohistochemistry, it is positive in astrocytes, ganglion cells and some ependymal cells of the central nervous system. In cancer, it is positive in ependymomas and in astrocytic tumors such as astrocytic gliomas, astrocytomas and glioblastomas.
References: Brain Research. 2007 July. 1158: 103–15. doi:10.1016/j.brainres.2007.04.070, PMID: 17555726; Neurology India. 2013. 61 (4): 383–8, PMID: 24005729; The Journal of Cell Biology. 1991 Mar. 112 (6): 1205–13. doi:10.1083/jcb.112.6.1205, PMID: 1999469; Neurosci Lett. 1996 May 3;209(1):29-32, PMID: 8734902.
Host
Mouse
Reactivity
Human
(tested or 100% immunogen sequence identity)
Clonality
IgG
Monoclonal
Clone
ABT-GFAP
Conjugations
Unconjugated
Purification
Affinity purified
Modifications
Unmodified
Immunogen
Synthetic GFAP
Applications
- IHC (1:200 - 1:400)
- IHC - Paraffin (1:50)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Usage
Use Heat-induced epitope retrieval (HIER) TRIS-EDTA of pH 8.0 Recommended IHC controls tissues are Brain, Astrocytoma, Glioma. Resulting localization is Cytoplasmic
Presentation
0.5% BSA, 0.1% Kathon, Tris-Buffered Saline, DI H2O and 50% glycerol
Storage
Store at -20°C for up to 1 year.
Restrictions
For research use only. Intended for use by laboratory professionals.
About GFAP
Validation
Human Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE)
See More About...
LSBio Ratings
PathPlus™ GFAP Antibody (clone ABT-GFAP) for IHC LS-B16150 has an LSBio Rating of
Laboratory Validation Score (5)
Learn more about The LSBio Ratings Algorithm
Publications (0)
Customer Reviews (0)
Featured Products
Species:
Pig, Human
Applications:
IHC, IHC - Paraffin, IHC - Frozen, Western blot, Immunoprecipitation, Flow Cytometry
Species:
Human, Monkey, Rat, Bat, Bovine, Horse, Rabbit
Applications:
IHC, IHC - Paraffin, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Species:
Pig, Human, Feline, Porcine
Applications:
IHC, IHC - Paraffin, ICC, Western blot, Immunoprecipitation
Species:
Mouse, Human, Rat
Applications:
IHC, Immunofluorescence, Western blot
Species:
Human
Applications:
IHC - Paraffin, Flow Cytometry
Species:
Human
Applications:
IHC - Paraffin, Western blot, Flow Cytometry
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 11/22/2024
Date Requested: 11/22/2024
