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| Catalog Number | Size | Price |
|---|---|---|
| LS-B16891-50 | 50 µl (1 mg/ml) | $460 |
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PathPlus™ Polyclonal Rabbit anti‑Human HSPA9 / Mortalin / GRP75 Antibody (C‑Terminus, IHC, IF, WB) LS‑B16891
PathPlus™ Polyclonal Rabbit anti‑Human HSPA9 / Mortalin / GRP75 Antibody (C‑Terminus, IHC, IF, WB) LS‑B16891
Note: This antibody replaces LS-C352329
Antibody:
HSPA9 / Mortalin / GRP75 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Application:
IHC-P, ICC, IF, WB
Reactivity:
Human, Mouse, Rat
Format:
Unconjugated, Unmodified
Toll Free North America
(800) 227-6666
(800) 227-6666For Research Use Only
Overview
Antibody:
HSPA9 / Mortalin / GRP75 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Application:
IHC-P, ICC, IF, WB
Reactivity:
Human, Mouse, Rat
Format:
Unconjugated, Unmodified
Specifications
Description
HSPA9 (Mortalin, GRP75) is a heat shock protein involved in cell proliferation, stress response and mitochondria maintenance. HSPA9 is of interest in neurodegenerative diseases including Alzheimer’s and Parkinson’s disease; it may have protective chaperone functions in the brain that help degrade and maintain lowered levels of aggregated or improperly folded proteins. In immunohistochemistry, HSPA9 has granular cytoplasmic positivity in all tissues.
References: Front Endocrinol (Lausanne). 2018; 9: 196, PMID: 29755410; J Alzheimers Dis. 2014;38(1):165-70. doi: 10.3233/JAD-130428, PMID: 23948933; J Alzheimers Dis. 2014;38(1):165-70, PMID: 23948933
Target
Human HSPA9 / Mortalin / GRP75
Synonyms
HSPA9 | Heat shock 70 kDa protein 9 | GRP-75 | Heat shock 70kD protein 9B | GRP75 | Mortalin-2 | Mortalin, perinuclear | Mot-2 | MOT2 | Peptide-binding protein 74 | MOT | MTHSP75 | p66-mortalin | PBP74 | CSA | HSPA9B | Mortalin
Host
Rabbit
Reactivity
Human, Mouse, Rat
(tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity chromatography
Modifications
Unmodified
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the C-Terminus of human GRP75.
Epitope
C-Terminus
Specificity
Recognizes endogenous levels of GRP75 protein.
Applications
- IHC - Paraffin (1:100)
- ICC (1:100 - 1:500)
- Immunofluorescence
- Western blot (1:500 - 1:1000)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Presentation
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Storage
Aliquot and store at -20°C for 1 year. Avoid freeze/thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About HSPA9 / Mortalin / GRP75
Validation
Human Skeletal Muscle: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Skeletal Muscle: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
See More About...
LSBio Ratings
PathPlus™ HSPA9 / Mortalin / GRP75 Antibody (C-Terminus) for IHC, ICC, IF/Immunofluorescence, WB/Western LS-B16891 has an LSBio Rating of
Laboratory Validation Score (5)
Learn more about The LSBio Ratings Algorithm
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Customer Reviews (0)
Featured Products
Species:
Human, Mouse, Rat
Applications:
IHC, IHC - Paraffin, Western blot
Species:
Human, Mouse, Rat
Applications:
IHC, IHC - Paraffin, Immunofluorescence, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Species:
Human, Mouse
Applications:
IHC, IHC - Paraffin, Western blot
Species:
Human, Mouse, Rat
Applications:
IHC - Paraffin, ICC, Immunofluorescence, Western blot, Immunoprecipitation
Species:
Human, Monkey, Mouse, Rat, Bovine, Dog, Guinea pig, Hamster, Pig, Rabbit, Sheep, Xenopus, Drosophila
Applications:
IHC, Western blot
Species:
Human, Mouse
Applications:
IHC, IHC - Paraffin, Western blot
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 11/24/2024
Date Requested: 11/24/2024
