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| Catalog Number | Size | Price |
|---|---|---|
| LS-B5579-100 | 100 µl | $485 |
1 of 2
2 of 2
PathPlus™ Polyclonal Rabbit anti‑Human HSPA9 / Mortalin / GRP75 Antibody (C‑Terminus, IHC, WB) LS‑B5579
PathPlus™ Polyclonal Rabbit anti‑Human HSPA9 / Mortalin / GRP75 Antibody (C‑Terminus, IHC, WB) LS‑B5579
Note: This antibody replaces LS-C79943
Toll Free North America
(800) 227-6666
(800) 227-6666For Research Use Only
Overview
Specifications
Description
HSPA9 (Mortalin, GRP75) is a heat shock protein involved in cell proliferation, stress response and mitochondria maintenance. HSPA9 is of interest in neurodegenerative diseases including Alzheimer’s and Parkinson’s disease; it may have protective chaperone functions in the brain that help degrade and maintain lowered levels of aggregated or improperly folded proteins. In immunohistochemistry, HSPA9 has granular cytoplasmic positivity in all tissues.
References: Front Endocrinol (Lausanne). 2018; 9: 196, PMID: 29755410; J Alzheimers Dis. 2014;38(1):165-70. doi: 10.3233/JAD-130428, PMID: 23948933; J Alzheimers Dis. 2014;38(1):165-70, PMID: 23948933
Target
Human HSPA9 / Mortalin / GRP75
Synonyms
HSPA9 | Heat shock 70 kDa protein 9 | GRP-75 | Heat shock 70kD protein 9B | GRP75 | Mortalin-2 | Mortalin, perinuclear | Mot-2 | MOT2 | Peptide-binding protein 74 | MOT | MTHSP75 | p66-mortalin | PBP74 | CSA | HSPA9B | Mortalin
Host
Rabbit
Reactivity
Human, Mouse, Rat
(tested or 100% immunogen sequence identity)
Clonality
IgG
Polyclonal
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic peptide from C-Terminus of human HSPA9 (P38646, NP_004125). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Galago, Marmoset, Mouse, Rat, Bat, Hamster, Elephant, Rabbit, Horse, Drosophila (100%); Dog, Pig, Guinea pig (92%); Opossum, Xenopus (90%); Bovine (84%).
Epitope
C-Terminus
Specificity
Human HSPA9 / GRP75
Applications
- IHC
- IHC - Paraffin (5 µg/ml)
- Western blot
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Usage
ELISA titer using peptide based assay: 1:62500. Western Blot: Suggested dilution at 1 ug/ml in 5% skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1:50000 - 100000 as second antibody.
Presentation
PBS, 0.09% sodium azide, 2% sucrose
Storage
Short term: Store at 2-8°C. Long term: Aliquot and store at -20°C. Avoid freeze/thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About HSPA9 / Mortalin / GRP75
Validation
Anti-GRP75 antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Anti-GRP75 antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
See More About...
LSBio Ratings
PathPlus™ HSPA9 / Mortalin / GRP75 Antibody (C-Terminus) for IHC, WB/Western LS-B5579 has an LSBio Rating of
Laboratory Validation Score (5)
Learn more about The LSBio Ratings Algorithm
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Featured Products
Species:
Human, Mouse, Rat
Applications:
IHC, IHC - Paraffin, Immunofluorescence, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Species:
Human, Mouse
Applications:
IHC, IHC - Paraffin, Western blot
Species:
Human, Mouse, Rat
Applications:
IHC - Paraffin, ICC, Immunofluorescence, Western blot, Immunoprecipitation
Species:
Human, Mouse, Rat
Applications:
IHC - Paraffin, ICC, Immunofluorescence, Western blot
Species:
Human, Monkey, Mouse, Rat, Bovine, Dog, Guinea pig, Hamster, Pig, Rabbit, Sheep, Xenopus, Drosophila
Applications:
IHC, Western blot
Species:
Human, Mouse
Applications:
IHC, IHC - Paraffin, Western blot
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 11/24/2024
Date Requested: 11/24/2024
