Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Forgot password?
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Quick Order
Products
Antibodies
ELISA and Assay Kits
Research Areas
Infectious Disease
Resources
Purchasing
Reference Material
Contact Us
Location
Corporate Headquarters
Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States
Telephone Numbers
Customer Service: (800) 227-6666 / (650) 697-3600
Contact Us
Additional Contact Details
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Forgot password?
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Quick Order
| Catalog Number | Size | Price |
|---|---|---|
| LS-A10761-50 | 50 µg (1 mg/ml) | $460 |
1 of 5
2 of 5
3 of 5
4 of 5
5 of 5
PathPlus™ Polyclonal Rabbit anti‑Human KRT18 / CK18 / Cytokeratin 18 Antibody (IHC) LS‑A10761
PathPlus™ Polyclonal Rabbit anti‑Human KRT18 / CK18 / Cytokeratin 18 Antibody (IHC) LS‑A10761
Antibody:
KRT18 / CK18 / Cytokeratin 18 Rabbit anti-Human Polyclonal Antibody
Application:
IHC-P, SWB
Format:
Unconjugated, Unmodified
Overview
Antibody:
KRT18 / CK18 / Cytokeratin 18 Rabbit anti-Human Polyclonal Antibody
Application:
IHC-P, SWB
Format:
Unconjugated, Unmodified
Specifications
Description
Cytokeratin 18 (KRT18, CK18) is a Type I intermediate filament chain keratin that is expressed in simple non-stratified epithelial tissues, eccrine glands, trophoblasts and endothelia of veins and lymphatics. Along with KRT8, KRT18 protects the liver from stress-induced injury and apoptosis. Mutations in this gene have been linked to cryptogenic cirrhosis and a variety of liver diseases, particularly after alcohol or viral infections. It is also a serum marker for breast carcinoma and late stage bladder carcinoma. It is positive in a variety of adenocarcinomas and hepatocellular carcinoma, and is generally negative in squamous cell carcinomas.
References: Gastroenterol 2005 129(3):885; Hepatology 2007 46(5):1639; Am J Clin Path 123(1):66; Clin Biochem 35(4):327; Histopath 1993 23(1):45
Target
Human KRT18 / CK18 / Cytokeratin 18
Synonyms
KRT18 | CK-18 | Cytokeratin 18 | Cytokeratin-18 | K18 | Keratin 18 | CYK18 | Keratin-18
Host
Rabbit
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
LP-10761, synthetic peptide
Applications
- IHC - Paraffin (0.6 - 1.25 µg/ml)
- Simple WesternBlot (20 µg/ml)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About KRT18 / CK18 / Cytokeratin 18
Validation
Human Pancreas: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Pancreas: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)
Anti-KRT18 antibody (LS-A10761, 20 µg/mL) yields a specific band on capillary Western analysis (Protein Simple, WES, 12-230 kDa separation module) in 0.25 mg/mL human cytokeratin 18 overexpression lysate.
Anti-KRT18 antibody (LS-A10761, 20 µg/mL) yields a specific band on capillary Western analysis (Protein Simple, WES, 12-230 kDa separation module) in 0.25 mg/mL human cytokeratin 18 overexpression lysate.
See More About...
LSBio Ratings
PathPlus™ KRT18 / CK18 / Cytokeratin 18 Antibody for IHC LS-A10761 has an LSBio Rating of
Laboratory Validation Score (5)
Learn more about The LSBio Ratings Algorithm
Publications (0)
Customer Reviews (0)
Featured Products
Species:
Human, Monkey, Mouse, Rat, Bat, Bovine, Guinea pig, Horse, Pig, Rabbit, Xenopus
Applications:
IHC, IHC - Paraffin, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Species:
Human
Applications:
IHC, IHC - Paraffin, IHC - Frozen
Species:
Human
Applications:
IHC, IHC - Paraffin, ICC, Western blot, Immunoprecipitation, Flow Cytometry, ELISA
Species:
Human, Mammal
Applications:
IHC, IHC - Paraffin, ICC, Western blot, Immunoprecipitation, Flow Cytometry, ELISA
Species:
Human
Applications:
IHC, IHC - Paraffin, ICC, Western blot, Immunoprecipitation, ELISA
Species:
Human
Applications:
IHC, IHC - Paraffin, ICC, Western blot
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 12/21/2024
Date Requested: 12/21/2024
