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Catalog Number Size Price
LS-B14231-100 100 µg (1 mg/ml) $460 
KRT5 / CK5 / Cytokeratin 5 Antibody - Human Skin: Formalin-Fixed, Paraffin-Embedded (FFPE)
KRT5 / CK5 / Cytokeratin 5 Antibody - Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)
KRT5 / CK5 / Cytokeratin 5 Antibody - Western blot of Cytokeratin 5 antibody
KRT5 / CK5 / Cytokeratin 5 Antibody - Western blot of Cytokeratin 5 antibody
KRT5 / CK5 / Cytokeratin 5 Antibody - Human Skin: Formalin-Fixed, Paraffin-Embedded (FFPE)
KRT5 / CK5 / Cytokeratin 5 Antibody - Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)
KRT5 / CK5 / Cytokeratin 5 Antibody - Western blot of Cytokeratin 5 antibody
KRT5 / CK5 / Cytokeratin 5 Antibody - Western blot of Cytokeratin 5 antibody
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PathPlus™ Polyclonal Rabbit anti‑Human KRT5 / CK5 / Cytokeratin 5 Antibody (510‑590 aa, C‑terminal, IHC, IF, WB) LS‑B14231

PathPlus™ Polyclonal Rabbit anti‑Human KRT5 / CK5 / Cytokeratin 5 Antibody (510‑590 aa, C‑terminal, IHC, IF, WB) LS‑B14231

Note: This antibody replaces LS-C383059
Antibody:
KRT5 / CK5 / Cytokeratin 5 Rabbit anti-Human Polyclonal (510-590 aa, C-terminal) Antibody
Application:
IHC, IHC-P, IF, WB, ELISA
Reactivity:
Human, Mouse, Rat
Format:
Unconjugated, Unmodified
Price
Catalog Number
$460
LS-B14231-100
Toll Free North America
206-374-1102
For Research Use Only

Overview

Antibody:
KRT5 / CK5 / Cytokeratin 5 Rabbit anti-Human Polyclonal (510-590 aa, C-terminal) Antibody
Application:
IHC, IHC-P, IF, WB, ELISA
Reactivity:
Human, Mouse, Rat
Format:
Unconjugated, Unmodified

Specifications

Description
KRT5 (Cytokeratin 5, CK5) is a protein that dimerizes with keratin 14 to form the intermediate filament that form the cytoskeleton of basal epithelial cells. It is useful for identifying myoepithelial cells and basal cells in the breast, skin, salivary glands, and prostate. It is present in the skin, the mucosa of the oral cavity, oropharynx, hypopharynx, and larynx, and in mitotically active basal cells of the skin. It is commonly positive in squamous carcinomas of the head and neck, as well as in mesotheliomas. Mutations in KRT5 cause epidermolysis bullosa simplex. Commonly used with Cytokeratin 6, the CK5/6 marker is useful for the identification of mesotheliomas as well as identifying the presence of basal epithelium in benign glands versus malignant prostate and breast carcinomas, where the basal layer is lost. References: Int J Clin Exp pathol 2008 1(1):19; Histopathology 1997 31:140; J Cell Sci 1994 107(4):765
Target
Human KRT5 / CK5 / Cytokeratin 5
Synonyms
KRT5 | 58 kd cytokeratin | 58 kDa cytokeratin | CK5 | CK-5 | Cytokeratin-5 | DDD | EBS2 | Keratin 5 | KRT5A | Type-II keratin Kb5 | Cytokeratin 5 | K5 | Keratin-5
Host
Rabbit
Reactivity
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthesized peptide derived from human Cytokeratin 5
Epitope
510-590 aa, C-terminal
Specificity
Cytokeratin 5 Polyclonal Antibody detects endogenous levels of Cytokeratin 5 protein.
Applications
  • IHC
  • IHC - Paraffin (5 µg/ml)
  • Immunofluorescence (1:200 - 1:1000)
  • Western blot (1:500 - 1:2000)
  • ELISA (1:10000)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Presentation
PBS, 0.02% Sodium Azide, 50% Glycerol, 0.5% BSA
Storage
Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About KRT5 / CK5 / Cytokeratin 5
P13647 NM_000424 NP_000415.2

Validation

KRT5 / CK5 / Cytokeratin 5 Antibody - Human Skin: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Skin: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Skin: Formalin-Fixed, Paraffin-Embedded (FFPE)

KRT5 / CK5 / Cytokeratin 5 Antibody - Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)

LSBio Ratings

PathPlus™ KRT5 / CK5 / Cytokeratin 5 Antibody (510-590 aa, C-terminal) for IHC, IF/Immunofluorescence, WB/Western, ELISA LS-B14231 has an LSBio Rating of
Laboratory Validation Score (5)

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Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 10/9/2024