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Catalog Number Size Price
LS-B12196-50 50 µg (1 mg/ml) $440 
KRT5 / CK5 / Cytokeratin 5 Antibody - Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)
KRT5 / CK5 / Cytokeratin 5 Antibody - Western blot using CK5 mouse monoclonal antibody against A431 (1), MCF-7 (2), HeLa (3) and HepG2 (4) cell lysate.
KRT5 / CK5 / Cytokeratin 5 Antibody - Western blot using CK5 monoclonal antibody against human CK5 recombinant protein. (Expected MW is 47.8 kDa)
KRT5 / CK5 / Cytokeratin 5 Antibody - Black: Control Antigen (100ng); Purple: Antigen (10ng); Blue: Antigen (50ng); Red: Antigen (100ng);
KRT5 / CK5 / Cytokeratin 5 Antibody - Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)
KRT5 / CK5 / Cytokeratin 5 Antibody - Western blot using CK5 mouse monoclonal antibody against A431 (1), MCF-7 (2), HeLa (3) and HepG2 (4) cell lysate.
KRT5 / CK5 / Cytokeratin 5 Antibody - Western blot using CK5 monoclonal antibody against human CK5 recombinant protein. (Expected MW is 47.8 kDa)
KRT5 / CK5 / Cytokeratin 5 Antibody - Black: Control Antigen (100ng); Purple: Antigen (10ng); Blue: Antigen (50ng); Red: Antigen (100ng);
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PathPlus™ Monoclonal Mouse anti‑Human KRT5 / CK5 / Cytokeratin 5 Antibody (clone 2C2B4, aa316‑590, IHC, WB) LS‑B12196

PathPlus™ Monoclonal Mouse anti‑Human KRT5 / CK5 / Cytokeratin 5 Antibody (clone 2C2B4, aa316‑590, IHC, WB) LS‑B12196

Note: This antibody replaces LS-C191848
Antibody:
KRT5 / CK5 / Cytokeratin 5 Mouse anti-Human Monoclonal (aa316-590) (2C2B4) Antibody
Application:
IHC, IHC-P, WB, Flo, ELISA
Reactivity:
Human
Format:
Unconjugated, Unmodified
Price
Catalog Number
$440
LS-B12196-50
Toll Free North America
206-374-1102
For Research Use Only

Overview

Antibody:
KRT5 / CK5 / Cytokeratin 5 Mouse anti-Human Monoclonal (aa316-590) (2C2B4) Antibody
Application:
IHC, IHC-P, WB, Flo, ELISA
Reactivity:
Human
Format:
Unconjugated, Unmodified

Specifications

Description
KRT5 (Cytokeratin 5, CK5) is a protein that dimerizes with keratin 14 to form the intermediate filament that form the cytoskeleton of basal epithelial cells. It is useful for identifying myoepithelial cells and basal cells in the breast, skin, salivary glands, and prostate. It is present in the skin, the mucosa of the oral cavity, oropharynx, hypopharynx, and larynx, and in mitotically active basal cells of the skin. It is commonly positive in squamous carcinomas of the head and neck, as well as in mesotheliomas. Mutations in KRT5 cause epidermolysis bullosa simplex. Commonly used with Cytokeratin 6, the CK5/6 marker is useful for the identification of mesotheliomas as well as identifying the presence of basal epithelium in benign glands versus malignant prostate and breast carcinomas, where the basal layer is lost. References: Int J Clin Exp pathol 2008 1(1):19; Histopathology 1997 31:140; J Cell Sci 1994 107(4):765
Target
Human KRT5 / CK5 / Cytokeratin 5
Synonyms
KRT5 | 58 kd cytokeratin | 58 kDa cytokeratin | CK5 | CK-5 | Cytokeratin-5 | DDD | EBS2 | Keratin 5 | KRT5A | Type-II keratin Kb5 | Cytokeratin 5 | K5 | Keratin-5
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG1 Monoclonal
Clone
2C2B4
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Unmodified
Immunogen
Purified recombinant fragment of human CK5 (AA: 316-590) expressed in E. Coli.
Epitope
aa316-590
Specificity
Human
Applications
  • IHC
  • IHC - Paraffin (10 µg/ml)
  • Western blot
  • Flow Cytometry (1:200 - 1:400)
  • ELISA (1:10000)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Presentation
PBS, 0.05% Sodium Azide
Storage
Short term: store at 4°C. Long term: store at -20°C.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About KRT5 / CK5 / Cytokeratin 5
P13647 NM_000424 NP_000415.2

Validation

KRT5 / CK5 / Cytokeratin 5 Antibody - Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)

LSBio Ratings

PathPlus™ KRT5 / CK5 / Cytokeratin 5 Antibody (aa316-590, clone 2C2B4) for IHC, WB/Western, Flow, ELISA LS-B12196 has an LSBio Rating of
Laboratory Validation Score (5)

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Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 10/9/2024