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| Catalog Number | Size | Price |
|---|---|---|
| LS-A561-50 | 50 µg (1 mg/ml) | $460 |
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PathPlus™ Polyclonal Rabbit anti‑Human RXFP1/ LGR7 Antibody (C‑Terminus, IHC) LS‑A561
PathPlus™ Polyclonal Rabbit anti‑Human RXFP1/ LGR7 Antibody (C‑Terminus, IHC) LS‑A561
Note: This antibody replaces LS-C67002
Antibody:
RXFP1/ LGR7 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Application:
IHC, IHC-P
Reactivity:
Human
Format:
Unconjugated, Unmodified
Overview
Antibody:
RXFP1/ LGR7 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Application:
IHC, IHC-P
Reactivity:
Human
Format:
Unconjugated, Unmodified
Specifications
Description
Relaxin/insulin-like family peptide receptor 1 (RXFP1) is a receptor mediated by G proteins that participates in stimulating adenylate cyclase and increasing cAMP. Binding of the ligand may also activate a tyrosine kinase pathway that inhibits the activity of a phosphodiesterase that degrades cAMP.
References: The UniProt Consortium. Nucleic Acids Res. 47: D506-515 (2019); Nucleic Acids Res. 2016 Jan 4;44(D1):D733-45, PMID:26553804
Target
Human RXFP1/ LGR7
Synonyms
RXFP1 | LGR7 | LGR7.1 | LGR7.10 | LGR7.2 | RXFPR1 | Relaxin receptor 1
Host
Rabbit
Reactivity
Human
(tested or 100% immunogen sequence identity)
Predicted
Monkey (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic 19 amino acid peptide from C-Terminus of human RXFP1. Percent identity with other species by BLAST analysis: Human, Gorilla, Orangutan (100%); Gibbon, Monkey (95%); Marmoset (84%).
Epitope
C-Terminus
Specificity
Human RXFP1. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except ANGPT2 (47%).
Applications
- IHC
- IHC - Paraffin (20 µg/ml)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About RXFP1/ LGR7
Validation
Brain, Thalamus, neurons and glia
Brain, Thalamus, neurons and glia
Brain, Medulla, neurons
Brain, Medulla, neurons
Brain, Temporal Cortex, neurons and glia
Brain, Temporal Cortex, neurons and glia
Anti-RXFP1/ LGR7 antibody IHC of human Prostate, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-RXFP1/ LGR7 antibody IHC of human Prostate, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-RXFP1/ LGR7 antibody IHC of human Breast, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-RXFP1/ LGR7 antibody IHC of human Breast, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)
See More About...
LSBio Ratings
PathPlus™ RXFP1/ LGR7 Antibody (C-Terminus) for IHC LS-A561 has an LSBio Rating of
Laboratory Validation Score (5)
Learn more about The LSBio Ratings Algorithm
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Featured Products
Species:
Human
Applications:
IHC, IHC - Paraffin
Species:
Human, Pig
Applications:
IHC, IHC - Paraffin
Species:
Human
Applications:
IHC, IHC - Paraffin
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 11/3/2024
Date Requested: 11/3/2024
