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Receptor for relaxins. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. Binding of the ligand may also activate a tyrosine kinase pathway that inhibits the activity of a phosphodiesterase that degrades cAMP.
Gene Name: | relaxin/insulin-like family peptide receptor 1 |
Family/Subfamily: | GPCR , Relaxin |
Synonyms: | RXFP1, LGR7, LGR7.1, LGR7.10, LGR7.2, RXFPR1, Relaxin receptor 1 |
Target Sequences: | NM_021634 NP_067647.2 Q9HBX9 |
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