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| Catalog Number | Size | Price |
|---|---|---|
| LS-A566-50 | 50 µg (1 mg/ml) | $440 |
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PathPlus™ Polyclonal Rabbit anti‑Human RXFP1/ LGR7 Antibody (N‑Terminus, IHC) LS‑A566
PathPlus™ Polyclonal Rabbit anti‑Human RXFP1/ LGR7 Antibody (N‑Terminus, IHC) LS‑A566
Antibody:
RXFP1/ LGR7 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Application:
IHC, IHC-P
Reactivity:
Human
Format:
Unconjugated, Unmodified
Overview
Antibody:
RXFP1/ LGR7 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Application:
IHC, IHC-P
Reactivity:
Human
Format:
Unconjugated, Unmodified
Specifications
Description
Relaxin/insulin-like family peptide receptor 1 (RXFP1) is a receptor mediated by G proteins that participates in stimulating adenylate cyclase and increasing cAMP. Binding of the ligand may also activate a tyrosine kinase pathway that inhibits the activity of a phosphodiesterase that degrades cAMP.
References: The UniProt Consortium. Nucleic Acids Res. 47: D506-515 (2019); Nucleic Acids Res. 2016 Jan 4;44(D1):D733-45, PMID:26553804
Target
Human RXFP1/ LGR7
Synonyms
RXFP1 | LGR7 | LGR7.1 | LGR7.10 | LGR7.2 | RXFPR1 | Relaxin receptor 1
Host
Rabbit
Reactivity
Human
(tested or 100% immunogen sequence identity)
Predicted
Monkey, Mouse, Rat, Bovine (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic 20 amino acid peptide from N-Terminus extracellular domain of human RXFP1. Percent identity with other species by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey (100%); Mouse, Rat (95%); Marmoset, Bovine (90%); Elephant, Panda, Dog, Horse, Pig (85%); Rabbit, Opossum (80%).
Epitope
N-Terminus
Specificity
Human RXFP1. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Applications
- IHC
- IHC - Paraffin (10 - 13 µg/ml)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About RXFP1/ LGR7
Validation
Skin, melanoma
Skin, melanoma
Anti-RXFP1 antibody IHC of human uterus, endometrium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-RXFP1 antibody IHC of human uterus, endometrium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Brain, Parkinson's Disease, neuron
Brain, Parkinson's Disease, neuron
Brain, Cortex, neurons and glia
Brain, Cortex, neurons and glia
See More About...
LSBio Ratings
PathPlus™ RXFP1/ LGR7 Antibody (N-Terminus) for IHC LS-A566 has an LSBio Rating of
Publications (4)
Laboratory Validation Score (5)
Learn more about The LSBio Ratings Algorithm
Publications (1)
Relaxin modulates proinflammatory cytokine secretion from human decidual macrophages. Horton JS, Yamamoto SY, Bryant-Greenwood GD. Biology of reproduction. 2011 Oct;85:788-97.
Customer Reviews (0)
Featured Products
Species:
Human
Applications:
IHC, IHC - Paraffin
Species:
Human, Pig
Applications:
IHC, IHC - Paraffin
Species:
Human
Applications:
IHC, IHC - Paraffin
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 11/24/2024
Date Requested: 11/24/2024
