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| Catalog Number | Size | Price |
|---|---|---|
| LS-B16217-0.05 | 0.05 ml | $460 |
PathPlus™ Monoclonal Mouse anti‑Human TG / Thyroglobulin Antibody (Concentrated, IHC, WB) LS‑B16217
PathPlus™ Monoclonal Mouse anti‑Human TG / Thyroglobulin Antibody (Concentrated, IHC, WB) LS‑B16217
Note: This antibody replaces LS-C757400
Antibody:
TG / Thyroglobulin Mouse anti-Human Monoclonal (Concentrated) Antibody
Application:
IHC-P, WB, ELISA
Reactivity:
Human
Format:
Unconjugated, Concentrated
Other formats:
Toll Free North America
(800) 227-6666
(800) 227-6666For Research Use Only
Overview
Antibody:
TG / Thyroglobulin Mouse anti-Human Monoclonal (Concentrated) Antibody
Application:
IHC-P, WB, ELISA
Reactivity:
Human
Format:
Unconjugated, Concentrated
Other formats:
Specifications
Description
Thyroglobulin (TG) is a protein synthesized by follicular cells of the thyroid, and is the precursor for thyroid hormones T3 and T4. Serum thyroglobulin measurements can be used as a marker for thyroid tumors, particularly in the postoperative management period, as well as a sensitive biomarker of iodine status in iodine deficiency states. Mutations in this gene are implicated in thyroid dyshormonogenesis with goiter, and congenital hypothyroidism. Polymorphisms are associated with autoimmune thyroid diseases such as Grave’s and Hashimoto’s thyroiditis.
References: Nature Clin Practice 2008 4(4):223; Thyroid 2014 24(8):1195; Clin Endocrin 2004 61(2):263; Mol Med Reports 2015 12(3):4469
Target
Human TG / Thyroglobulin
Synonyms
TG | AITD3 | TDH3 | Thyroglobulin | TGN
Host
Mouse
Reactivity
Human
(tested or 100% immunogen sequence identity)
Clonality
IgG1
Monoclonal
Conjugations
Unconjugated
Purification
Protein A/G purified
Modifications
Concentrated.
Also available Ready-to-Use.
Immunogen
Recombinant Human Thyroglobulin protein.
Applications
- IHC - Paraffin (1:100)
- Western blot (1:100 - 1:200)
- ELISA (1:100 - 1:200)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Usage
Dilute antibody to its recommended working dilution using the same buffer defined in the Presentation. Manual IHC Protocol: 1) Perform Heat-Induced Epitope Retrieval at pH 9 for 10 to 30 minutes. 2) Block in peroxidase blocking solution for 5 minutes at room temperature. (Not required if using Alkaline Phosphatase System) 3) Dilute antibody 1:100-1:200 before applying. Incubate antibody for 10 to 30 minutes at room temperature. 4) Add secondary antibody and incubate for 20 to 30 minutes at room temperature. 5) Add DAB or Fast Red and incubate for 5 to 10 minutes at room temperature. 6) Counterstain with hematoxylin for 0.5 to 5 minutes, depending on the hematoxylin used. Rinse with distilled water and blueing solution for 30 seconds. Dehydrate and apply coverslip.
Presentation
Tris, pH 7.3-7.7, 1% BSA, <0.1% Sodium Azide
Storage
Store at 2°C to 8°C. Do not freeze.
Restrictions
For research use only. Intended for use by laboratory professionals.
About TG / Thyroglobulin
Validation
Human Thyroid: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Thyroid: Formalin-Fixed, Paraffin-Embedded (FFPE)
See More About...
LSBio Ratings
PathPlus™ TG / Thyroglobulin Antibody (Concentrated) for IHC, WB/Western, ELISA LS-B16217 has an LSBio Rating of
Laboratory Validation Score (5)
Learn more about The LSBio Ratings Algorithm
Publications (0)
Customer Reviews (0)
Featured Products
Species:
Human
Applications:
IHC, IHC - Paraffin, ELISA
Species:
Human
Applications:
IHC, IHC - Paraffin, ELISA
Species:
Human
Applications:
IHC - Paraffin
Species:
Human
Applications:
IHC - Paraffin
Species:
Human, Mouse, Rat, Dog
Applications:
IHC, IHC - Paraffin, IHC - Frozen, Western blot, ELISA
Species:
Human, Bovine
Applications:
IHC, IHC - Paraffin, ELISA
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 11/12/2024
Date Requested: 11/12/2024
