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Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
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BRAF / B-Raf

v-raf murine sarcoma viral oncogene homolog B

BRAF / B-Raf is a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene.

Gene Name: v-raf murine sarcoma viral oncogene homolog B
Family/Subfamily: Protein Kinase , Raf
Synonyms: BRAF, 94 kDa B-raf protein, B-raf, BRAF1, B Raf, Proto-oncogene B-Raf, p94, B-RAF1, NS7, ONCOGENE BRAF, RAFB1
Target Sequences: NM_004333 NP_004324.2 P15056

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Products
Antibodies (162)
Primary (162)
BRAF / B-Raf (162)
Human (156)
Mouse (60)
Rat (43)
Bat (1)
Bovine (1)
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Horse (1)
Monkey (12)
Pig (1)
Sheep (1)
Zebrafish (1)
IHC (89)
IHC-Fr (2)
IHC-P (34)
WB (125)
Flo (10)
DB (26)
ELISA (79)
ICC (1)
IF (24)
IP (16)
Peptide-ELISA (12)
rabbit (123)
mouse (38)
chicken (1)
Product Group
IHCPlus (3)
PathPlus Cancer (2)
PathPlus Cancer Pathology (2)
Ig (1)
IgG (100)
IgG1 (22)
IgG1,k (1)
IgG2a (9)
IgG2b (4)
IgY (1)
monoclonal mc (38)
polyclonal pc (122)
recombinant monoclonal rmc (2)
1H12 (1)
1H12F1 (1)
3C6 (1)
OTI1D2 (2)
OTI1D4 (2)
OTI1E2 (2)
OTI1G6 (2)
OTI1G8 (2)
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APC Conjugated (9)
Azide-free (8)
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PE Conjugated (9)
Ready-to-Use (1)
Unconjugated (114)
pSer445 (9)
Ser445 (7)
Ser601 (7)
Thr400 (7)
aa424-453 (7)
pThr598 (7)
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pThr439 (6)
pSer446 (5)
pThr599 (4)
550-630 aa (2)
Mutation V600E (2)
aa25-75 (2)
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380-460 aa (1)
540-620 aa (1)
700-780 aa (1)
Ab-598 (1)
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Internal (1)
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aa171-220 (1)
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aa38-230 (1)
aa390-439 (1)
aa411-460 (1)
aa571-620 (1)
aa576-625 (1)
aa754-765 (1)
p446 (1)
p601 (1)
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pSer728 (1)
No (162)
BRAF / B-Raf Antibody - Anti-BRAF antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.
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Cancer Pathology
Cancer
BRAF / B-Raf Mouse anti-Human Monoclonal (1H12) Antibody
Human
ELISA, IF, IHC-P, WB
Unconjugated
50 µl/$440
BRAF / B-Raf Antibody - Immunohistochemical analysis of B-RAF staining in human prostate cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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BRAF / B-Raf Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Chicken, Zebrafish, Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
100 µl/$299
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BRAF / B-Raf Rabbit anti-Human Polyclonal (aa754-765) Antibody
Human
WB
Unconjugated
100 µg/$572
BRAF / B-Raf Antibody - Immunohistochemistry analysis of paraffin-embedded human lymph node tissue, using B-RAF Antibody. The picture on the right is blocked with the synthesized peptide.
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BRAF / B-Raf Rabbit anti-Human Polyclonal (aa576-625) Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
BRAF / B-Raf Antibody - Anti-BRAF / B-Raf antibody IHC staining of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Select
Cancer Pathology
Cancer
BRAF / B-Raf Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, IHC-P, WB
Unconjugated
0.05 mg/$440
BRAF / B-Raf Antibody - Anti-BRAF antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.
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BRAF / B-Raf Mouse anti-Human Monoclonal (1H12F1) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$485
BRAF / B-Raf Antibody - IHC of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-BRAF mouse monoclonal antibody.
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BRAF / B-Raf Mouse anti-Human Monoclonal (OTI5A9) Antibody
Human, Monkey
Flo, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
BRAF / B-Raf Antibody - IHC of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-BRAF mouse monoclonal antibody.
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BRAF / B-Raf Mouse anti-Human Monoclonal (Carrier-free) (OTI5A9) Antibody
Human, Monkey
Flo, IF, IHC, IP, WB
Unconjugated, Carrier-free
100 µg/$511
BRAF / B-Raf Antibody - Formalin-fixed and paraffin-embedded human brain tissue reacted with BRAF Antibody (S445), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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BRAF / B-Raf Rabbit anti-Human Polyclonal (Ser445) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
400 µl/$393
BRAF / B-Raf Antibody - Human Thyroid Carcinoma: Formalin-Fixed, Paraffin-Embedded (FFPE)
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BRAF / B-Raf Rabbit anti-Human Recombinant Monoclonal (Mutation V600E) (Ready-to-Use) (RM8) Antibody
Human
IHC-Fr, IHC-P
Unconjugated, Ready-to-Use
3 ml/$460; 7 ml/$772; 15 ml/$1,119
BRAF / B-Raf Antibody - Anti-BRAF antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
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BRAF / B-Raf Rabbit anti-Human Polyclonal (aa411-460) Antibody
Mouse, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$460
BRAF / B-Raf Antibody - IHC of paraffin-embedded breast tissue using anti-BRAF mouse monoclonal antibody. (Dilution 1:50).
Select
BRAF / B-Raf Mouse anti-Human Monoclonal (OTI1G8) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
BRAF / B-Raf Antibody - Anti-BRAF antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
Select
BRAF / B-Raf Rabbit anti-Human Polyclonal (aa171-220) Antibody
Mouse, Human
IF, IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$460
BRAF / B-Raf Antibody - Immunohistochemical staining of paraffin-embedded Adenocarcinoma of breast tissue using anti-BRAF mouse monoclonal antibody. (Dilution 1:50).
Select
BRAF / B-Raf Mouse anti-Human Monoclonal (OTI1E2) Antibody
Flo, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
BRAF / B-Raf Antibody - Immunohistochemical staining of paraffin-embedded Adenocarcinoma of breast tissue using anti-BRAF mouse monoclonal antibody. (Dilution 1:50).
Select
BRAF / B-Raf Mouse anti-Human Monoclonal (Carrier-free) (OTI1E2) Antibody
Human
Flo, IF, IP, WB
Unconjugated, Carrier-free
100 µg/$511
BRAF / B-Raf Antibody - IHC of paraffin-embedded Adenocarcinoma of breast tissue using anti-BRAF mouse monoclonal antibody. (Dilution 1:50).
Select
BRAF / B-Raf Mouse anti-Human Monoclonal (OTI1D4) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
BRAF / B-Raf Antibody - IHC of paraffin-embedded Adenocarcinoma of breast tissue using anti-BRAF mouse monoclonal antibody. (Dilution 1:50).
Select
BRAF / B-Raf Mouse anti-Human Monoclonal (Carrier-free) (OTI1D4) Antibody
Human
Flo, IF, IP, WB
Unconjugated, Carrier-free
100 µg/$511
Select
BRAF / B-Raf Rabbit anti-Human Polyclonal (700-780 aa) Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
BRAF / B-Raf Antibody - Formalin-fixed and paraffin-embedded human prostate carcinoma reacted with BRAF Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Select
BRAF / B-Raf Rabbit anti-Human Polyclonal (aa424-453) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
400 µl/$393
BRAF / B-Raf Antibody - IHC of paraffin-embedded breast tissue using anti-BRAF mouse monoclonal antibody. (Dilution 1:50).
Select
BRAF / B-Raf Mouse anti-Human Monoclonal (OTI3A7) Antibody
Dog, Rat, Human, Monkey
IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
BRAF / B-Raf Antibody - Immunohistochemical analysis of B-RAF staining in human liver cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Select
BRAF / B-Raf Rabbit anti-Human Polyclonal (Internal) Antibody
Chicken, Mouse, Dog, Rat, Human, Monkey
ICC, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$299
BRAF / B-Raf Antibody - Immunohistochemistry (IHC) analysis of paraffin-embedded human testis tissues with AEC staining using Raf-B Monoclonal Antibody.
Select
BRAF / B-Raf Mouse anti-Human Monoclonal Antibody
Mouse, Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$332; 100 µg/$404; 200 µg/$505
BRAF / B-Raf Antibody - Anti-BRAF mouse monoclonal antibody  immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY BRAF.
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BRAF / B-Raf Mouse anti-Human Monoclonal (Carrier-free) (OTI1D2) Antibody
Human
Flo, IF, IP, WB
Unconjugated, Carrier-free
100 µg/$511
BRAF / B-Raf Antibody - IHC of paraffin-embedded Ovary tissue using anti-BRAF mouse monoclonal antibody. (Dilution 1:50).
Select
BRAF / B-Raf Mouse anti-Human Monoclonal (Carrier-free) (OTI4C11) Antibody
Dog, Human
ELISA, IHC, IP, WB
Unconjugated, Carrier-free
100 µg/$511
BRAF / B-Raf Antibody - Peptide - + Immunohistochemistry analysis of paraffin-embedded human brain tissue using B-RAF antibody.
Select
BRAF / B-Raf Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$357
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).