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CCR7
chemokine (C-C motif) receptor 7
CCR7, a Chemokine Receptor, is involved in lymphocyte recirculation through secondary lymphoid organs and moving lymphocytes and dendritic cells into distinct tissue compartments. CCR7 is called the Epstein-Barr-induced receptor because it mediates Epstein-Barr viral effects on B lymphocytes. CCR7 expression is up-regulated in mature dendritic cells, B cells infected with EBV, and in CD4+ cells infected with human herpes virus 6 and 7. Immature dendritic cells have been shown to express chemokine receptor 5 (CCR5) and migrate in response to macrophage inflammatory protein-1alpha (MIP-1alpha), whereas mature dendritic cells switch to CCR7 expression and respond exclusively to MIP-3beta and 6Ckine. Maturing dendritic cells upregulate CCR7, which drives their migration to the T-cell areas of the draining lymph nodes where antigen is presented to naive T cells.
| Gene Name: | chemokine (C-C motif) receptor 7 |
| Family/Subfamily: | GPCR , Chemokine |
| Synonyms: | CCR7, BLR2, Chemokine (C-C) receptor 7, CD197, C-C CKR-7, CMKBR7, CC chemokine receptor 7, CCR-7, CD197 antigen, CDw197, EBI1, EVI1, MIP-3 beta receptor, C-c chemokine receptor 7, C-C chemokine receptor type 7, CC-CKR-7, Chemokine c-c motif receptor 7 |
| Target Sequences: | NM_001838 NP_001829.1 P32248 |
Publications (1)
1
Constitutive expression of the alpha4 integrin correlates with tumorigenicity and lymph node metastasis of the B16 murine melanoma. Rebhun RB, Cheng H, Gershenwald JE, Fan D, Fidler IJ, Langley RR. Neoplasia (New York, N.Y.). 2010 12:173-82. (WB)
[PubMed:20126475]
[PMC:PMC2814355]
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Fast Shipping
CCR7 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Bovine, Horse, Bat, Human, Monkey
ICC, IHC, IHC-P
Unconjugated
50 µg/$440
Neuroscience
Fast Shipping
CCR7 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
IHC, IHC-P
Unconjugated
50 µg/$460
Neuroscience
Fast Shipping
CCR7 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Bovine, Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$440
Neuroscience
Fast Shipping
CCR7 Rabbit anti-Human Polyclonal (Extracellular Domain) Antibody
Human
IHC, IHC-P
Unconjugated
50 µg/$440
CCR7 Goat anti-Mouse Polyclonal (aa2-22) Antibody
Mouse
ELISA, Flo, IHC-P, WB
Unconjugated
50 µg/$500
CCR7 Rat anti-Human Monoclonal (Biotin) (3D12) Antibody
Human
Flo
Biotin Conjugated
25 µg/$277; 100 µg/$382
CCR7 Rat anti-Mouse Monoclonal (4B12) Antibody
Mouse
Flo, Func, IHC, Neut
Unconjugated
100 µg/$951
CCR7 Rat anti-Mouse Monoclonal (PE, Cy7) (4B12) Antibody
Mouse
Flo
PE, Cy7 Conjugated
50 µg/$444; 100 µg/$531
CCR7 Rat anti-Mouse Monoclonal (APC) (4B12) Antibody
Mouse
Flo
APC Conjugated
10 µg/$247; 50 µg/$352; 100 µg/$435
CCR7 Mouse anti-Human Monoclonal (N-Terminus) (1987CT875.52.22) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$393
CCR7 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, ICC, IF, IHC
Unconjugated
50 µg/$294; 100 µg/$360
CCR7 Mouse anti-Human Monoclonal (aa11-37) Antibody
Human
WB
Unconjugated
0.1 ml/$393
CCR7 Mouse anti-Human Monoclonal (Cy5.5, PerCP) (G043H7) Antibody
Human
Flo
Cy5.5, PerCP Conjugated
20 Tests/$268; 100 Tests/$382; 200 Tests/$466
CCR7 Mouse anti-Human Monoclonal (PE) (G043H7) Antibody
Human
Flo
PE Conjugated
20 Tests/$248; 100 Tests/$325; 200 Tests/$382
CCR7 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
0.1 mg/$460
CCR7 Mouse anti-Human Monoclonal (4B7B8) Antibody
Human
ELISA, Flo, WB
Unconjugated
100 µl/$459
CCR7 Mouse anti-Human Monoclonal (7A5A9) Antibody
Human
ELISA, Flo, WB
Unconjugated
100 µl/$459
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Tissue Homogenates
1 Plate/$798
293T Cells
Myc-DDK (Flag)
42.87 kDa
20 µg/$150
CCR7 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, WB
Unconjugated
100 µl/$357
CCR7 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, Flo, IHC
Unconjugated
100 µg/$331
CCR7 Rabbit anti-Human Polyclonal Antibody
Human
ICC, IF, WB
Unconjugated
50 µg/$305; 100 µg/$357
CCR7 Rabbit anti-Human Polyclonal (140-220 aa, Internal) Antibody
Human, Monkey
ELISA, IF, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
CCR7 Rabbit anti-Human Polyclonal (aa170-219) Antibody
Human
IF, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
CCR7 Rabbit anti-Human Polyclonal Antibody
Human, Monkey
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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