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THBD / CD141 / Thrombomodulin
thrombomodulin
Thrombomodulin is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the activated protein C (protein Ca). Once evolved, protein Ca scissions the activated cofactors of the coagulation mechanism, factor Va and factor VIIIa, and thereby reduces the amount of thrombin generated.
| Gene Name: | thrombomodulin |
| Synonyms: | THBD, BDCA3, CD141 antigen, CD141, AHUS6, Fetomodulin, THPH12, TM, THRM, Thrombomodulin |
| Target Sequences: | NM_000361 NP_000352.1 P07204 |
Publications (2)
1
T cell infiltration on local CpG-B delivery in early-stage melanoma is predominantly related to CLEC9A +<sup> CD141 +<sup> cDC1 and CD14 +<sup> antigen-presenting cell recruitment. Bas D Koster #, Marta López González #, Mari Fcm van den Hout , Annelies W Turksma, Berbel Jr Sluijter, Barbara G Molenkamp, Paul Am van Leeuwen, Saskia Vosslamber, Rik J Scheper, Alfons Jm van den Eertwegh, M Petrousjka van den Tol, Ekaterina J Jordanova , Tanja D de Gruijl. Journal for immunotherapy of cancer. 2021 Mar;;9:e001962. [Full Text Article]
[PubMed:33737341]
[PMC:PMC7978250]
2
Transgenic Expression of Human Thrombomodulin Inhibits HMGB1-Induced Porcine Aortic Endothelial Cell Activation. Anjan K Bongoni, Nikolai Klymiuk, Eckhard Wolf, David Ayares, Robert Rieben, Peter J Cowan. Transplantation. 2016 September;100:1871-9. [Full Text Article]
[PubMed:27077599]
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Products
Antibodies
(83)
Type
Primary
(83)
Target
THBD / CD141 / Thrombomodulin
(83)
Reactivity
Human
(46)
Mouse
(14)
Rat
(23)
Dog
(8)
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(8)
Application
IHC
(7)
IHC-Fr
(2)
IHC-P
(13)
WB
(70)
Flo
(15)
ELISA
(19)
Func
(2)
ICC
(2)
IF
(5)
IP
(1)
Peptide-ELISA
(2)
Host
rabbit
(67)
mouse
(10)
goat
(1)
rat
(5)
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IHCPlus
(2)
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(2)
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(2)
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Ig
(2)
IgG
(11)
IgG1
(4)
IgG2a
(6)
IgG2a,k
(2)
IgG2b
(1)
IgG2b,k
(2)
Clonality
monoclonal mc
(13)
polyclonal pc
(68)
recombinant monoclonal rmc
(2)
Clone
2C6C3
(1)
461714
(1)
QBEND/40
(1)
rTHBD/1591
(2)
RTM96
(1)
RTM98
(1)
THBD/1591
(2)
THBD/1782
(2)
Format
APC
(6)
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(6)
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(3)
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(8)
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(2)
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(1)
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(6)
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(6)
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(6)
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(6)
PE Conjugated
(6)
Unconjugated
(39)
Epitope
aa31-167
(16)
aa279-493
(8)
aa31-169
(8)
aa324-480
(8)
aa325-481
(8)
C-Terminus
(3)
aa 69-194
(2)
aa19-515
(2)
500-580 aa, C-terminal
(1)
Extracellular Domain
(1)
N-Terminus
(1)
aa17-517
(1)
aa526-575
(1)
aa530-575
(1)
Publications
No
(83)
THBD / CD141 / Thrombomodulin Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
THBD / CD141 / Thrombomodulin Rat anti-Mouse Monoclonal (aa17-517) (461714) Antibody
Mouse
ELISA, Flo, ICC, IHC, IHC-Fr, WB
Unconjugated
100 µg/$896
THBD / CD141 / Thrombomodulin Rabbit anti-Human Polyclonal (aa31-169) Antibody
Pig, Human
WB
Unconjugated
100 µl/$299; 200 µl/$336; 500 µl/$462; 1 ml/$525; 2 ml/$677; 5 ml/$1,136
THBD / CD141 / Thrombomodulin Rat anti-Human Monoclonal Antibody
Human
Flo, Func, WB
Unconjugated
100 µg/$862
Cancer Pathology
Cancer
THBD / CD141 / Thrombomodulin Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
ICC, IHC, IHC-P, WB
Unconjugated
100 µl/$485
THBD / CD141 / Thrombomodulin Mouse anti-Human Monoclonal (aa19-515) Antibody
Human
Flo, IHC
Unconjugated
100 µg/$951
Cancer Pathology
Cancer
THBD / CD141 / Thrombomodulin Mouse anti-Human Recombinant Monoclonal (aa 69-194) (rTHBD/1591) Antibody
Human
ELISA, IHC-P
Unconjugated
100 µg/$525
THBD / CD141 / Thrombomodulin Rat anti-Human Monoclonal (RTM98) Antibody
Human
Flo, WB
Unconjugated
100 µg/$589
THBD / CD141 / Thrombomodulin Goat anti-Mouse Polyclonal (Extracellular Domain) (Biotin) Antibody
Mouse
Flo, WB
Biotin Conjugated
50 µg/$973
THBD / CD141 / Thrombomodulin Mouse anti-Human Monoclonal (THBD/1591) Antibody
Human
ELISA, Flo, IF, IHC-P, WB
Unconjugated
20 µg/$371; 100 µg/$574
THBD / CD141 / Thrombomodulin Mouse anti-Human Monoclonal (Azide-free, BSA-free) (THBD/1591) Antibody
Human
ELISA, Flo, IF, IHC-P, WB
Unconjugated, Azide-free, BSA-free
100 µg/$574
THBD / CD141 / Thrombomodulin Mouse anti-Human Monoclonal (aa19-515) (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$978
THBD / CD141 / Thrombomodulin Mouse anti-Human Monoclonal (THBD/1782) Antibody
Human
ELISA, Flo, IF, IHC-P
Unconjugated
20 µg/$371; 100 µg/$574
THBD / CD141 / Thrombomodulin Mouse anti-Human Monoclonal (Azide-free, BSA-free) (THBD/1782) Antibody
Human
ELISA, Flo, IF, IHC-P
Unconjugated, Azide-free, BSA-free
100 µg/$574
THBD / CD141 / Thrombomodulin Rabbit anti-Rat Polyclonal Antibody
Rat
ELISA
Unconjugated
100 µl/$412
THBD / CD141 / Thrombomodulin Rabbit anti-Human Polyclonal (aa325-481) (APC, Cy7) Antibody
Human
WB
APC, Cy7 Conjugated
100 µl/$476; 200 µl/$590; 500 µl/$1,069; 1 ml/$1,265; 2 ml/$1,771; 5 ml/$3,319
THBD / CD141 / Thrombomodulin Mouse anti-Human Monoclonal (QBEND/40) Antibody
Human
Flo, IHC, IHC-Fr, IHC-P, IP
Unconjugated
100 Tests/$1,556
THBD / CD141 / Thrombomodulin Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC-P, WB
Unconjugated
50 µl/$460
THBD / CD141 / Thrombomodulin Mouse anti-Human Monoclonal (2C6C3) Antibody
Human
ELISA, Flo, WB
Unconjugated
100 µg/$459
THBD / CD141 / Thrombomodulin Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
THBD / CD141 / Thrombomodulin Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
ELISA, Flo, WB
Unconjugated
200 µl/$393
THBD / CD141 / Thrombomodulin Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
ELISA, Flo, WB
Unconjugated
200 µl/$393
THBD / CD141 / Thrombomodulin Rat anti-Human Monoclonal (RTM96) Antibody
Human
Flo, Func, WB
Unconjugated
100 µg/$589
THBD / CD141 / Thrombomodulin Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$294; 100 µl/$360
THBD / CD141 / Thrombomodulin Rat anti-Human Monoclonal Antibody
Human
Flo, WB
Unconjugated
100 µg/$862
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of 83
product results
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